Results 201 to 210 of about 27,030 (231)

Ligandi TRPV1

2014
The present invention relates to high affinity compounds, able to bind the transient receptor potential cation channel, subfamily Vanilloid, type 1 or TRPV1. Being this receptor involved in pain processing and neurogenic inflammatory 5 responses and being up-regulated during chronic pain conditions, the compounds of the invention find particular ...
Brizzi A, AIELLO, Francesca, Corelli F.
openaire   +1 more source

TRPV1

2006
  +4 more sources

TRPV1 modulação

  Em meus estudos, observei que o segredo para modular o TRPV1 de forma segura e eficaz reside em trabalhar com moléculas que possuem massa molar entre 200 e 250 g/mol — uma faixa que parece quase mágica para equilibrar potência, seletividade e tolerabilidade.
openaire   +2 more sources

Controlled Activation of TRPV1 Channels on Microglia to Boost Their Autophagy for Clearance of Alpha‐Synuclein and Enhance Therapy of Parkinson's Disease

Advanced Materials, 2022

exaly  

TRPV1 is the burner

Pain
Annekathrin Alpes, Sofia Malek, Ralf Baron   +2 more
openaire   +2 more sources

The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept

Nature Reviews Drug Discovery, 2007
Arpad Szallasi, Daniel N Cortright, Szallasi Arpad   +2 more
exaly  

Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists

Medicinal Research Reviews, 2017
Stefania Gessi, Stefania Merighi, Pier Andrea Borea   +2 more
exaly  

TRPV1 Gene Knockout Impairs Postischemic Recovery in Isolated Perfused Heart in Mice

Circulation, 2005
Donna H Wang
exaly  

Cutaneous TRPV1+ Neurons Trigger Protective Innate Type 17 Anticipatory Immunity

Cell, 2019
Tara N Edwards, Jonhan Ho, Brian Davis
exaly  

TRPV1‐lineage neurons are required for thermal sensation

EMBO Journal, 2011
Mark Hoon, Santosh Mishra
exaly