Results 111 to 120 of about 4,775 (199)

Engineering vanilloid-sensitivity into the rat TRPV2 channel

, 2020
The TRPV1 channel is a detector of noxious stimuli, including heat, acidosis, vanilloid compounds and lipids. The gating mechanisms of the related TRPV2 channel are poorly understood because selective high affinity ligands are not available, and the ...
Peter M Blumberg, Chanhyung Bae, Feng Zhang, Sonya M Hanson, Kenton J Swartz, † ‡, Andres Jara-Oseguera, Simon Newstead, Larry V Pearce, Dmitriy Krepkiy   +9 more
core  

Funktion von Cavβ3, TRPC1 und TRPV2 in Endothelzellen des Mausgehirns [PDF]

Calcium (Ca2+) ist ein entscheidendes Signal-Ion, das an der Aufrechterhaltung der Integrität der Blut-Hirn-Schranke (BHS) beteiligt ist, die den Blutkreislauf vom zentralen Nervensystem trennt.
Kaiser, Nicolas
core   +1 more source

TRPV2 Modulation by Small Molecules and Lipids [PDF]

Biophysical Journal, 2021
Anna D. Protopopova, Ruth A. Pumroy, Jeanne de la Roche, Ferdinand M. Haug, Bárbara B. Sousa, Pamela N. Gallo, Gonçalo J.L. Bernardes, Andreas Leffler, Vera Y. Moiseenkova-Bell   +8 more
openaire   +1 more source

Aproximación a la estructura y función de TRPV1 y TRPV2

, 2013
[ES] Comparación diferencial entre las secuencias primarias de TRPV1 y TRPV2, dos canales iónicos con diversas implicaciones en enfermedades como el dolor agudo, la osteoartritis o el infarto de miocardio.
Doñate Macián, Pablo
core  

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2. [PDF]

Adv Sci (Weinh)
Zhu A, Wang H, Wang J, Liu X, Aierken A, Xu L, Liang P, Yang F.   +7 more
europepmc   +1 more source

Transient receptor potential vanilloid 2 functions as a directional driver for hepoxilin A₃-mediated neutrophil migration. [PDF]

Sci Adv
Feriotti C, Mercado-Lubo R, Bryford M, Ferrisi R, Gado F, Manera C, Liu K, Lu P, Lai Y, McCormick BA, Mrsny R.   +10 more
europepmc   +1 more source

Correction: Novel recombinant protein PK5-Gal-3C enhances the anti-tumor activity of T cells via binding with TRPV2. [PDF]

Cancer Immunol Immunother
Zhang G, Zhang W, Wei X, Wang Z, Wang F, Sun S, Xu H, Liu X, Zhang Q, Gao X.   +9 more
europepmc   +1 more source

Role of TRP channels in lymphatic function. [PDF]

Front Physiol
Cao X, Chen YL.
europepmc   +1 more source

Novel recombinant protein PK5-Gal-3C enhances the anti-tumor activity of T cells via binding with TRPV2. [PDF]

Cancer Immunol Immunother
Zhang G, Zhang W, Wei X, Wang Z, Wang F, Sun S, Xu H, Liu X, Zhang Q, Gao X.   +9 more
europepmc   +1 more source

Selective TRPV2 Antagonists Derived from the Natural Product Piperlongumine Inhibit Cancer Cell Migration and Metastasis. [PDF]

ACS Chem Biol
Kiely-Collins H, Tang C, Marques MC, Butron L, Lamberti A, Bossons N, Offensperger F, Brennsteiner V, Sousa B, Carvalho L, Ferrer-Montiel A, Corzana F, Winter GE, Fernandez-Carvajal A, Bernardes GJL.   +14 more
europepmc   +1 more source