Results 151 to 160 of about 9,155 (170)

Transient receptor potential cation channel subfamily V (TRPV) and its importance in asthma.

European Journal of Pharmacology, 2022
Transient receptor potential (TRP) ion channels play critical roles in physiological and pathological conditions. Increasing evidence has unveiled the contribution of TRP vanilloid (TRPV) family in the development of asthma. The TRPV family is a group (TRPV1-TRPV6) of polymodal channels capable of sensing thermal, acidic, mechanical stress, and osmotic
Jorge, Reyes-García, Abril, Carbajal-García, Luis M, Montaño   +2 more
openaire   +2 more sources

Changes in transient receptor potential cation channel superfamily V (TRPV) mRNA expression in the mouse inner ear ganglia after kanamycin challenge

Hearing Research, 2005
The transient receptor potential cation channel subfamily V (TRPV) is a non-specific cation ion channel receptor family that is gated by heat, protons, low extracellular osmolarity and arachidonic acid derivatives. Since some of these endogenous agonists of TRPV receptors are reactive oxygen intermediates produced by lipoxygenases, it has been ...
Tadashi, Kitahara, Ha-Sheng, Li, Carey D, Balaban   +2 more
openaire   +2 more sources

A novel actor in mechanotransduction: transient receptor potential cation channel vanilloid (TRPV) 1 in ventilator‐induced lung injury (VILI)

The FASEB Journal, 2017
Study objective Mechanical ventilation can damage the lung by causing endothelial barrier failure, edema formation and lung injury. Yet, the exact mechanisms underlying the mechanotransduction at the microvascular barrier are still unclear.
Laura Michalick, Wolfgang Liedtke, Wolfgang M. Kuebler   +2 more
openaire   +1 more source

Editorial [Hot Topic: New Potential Therapies from Vanilloid Transient Receptor Cation (TRPV) Channels (Executive Editors: V. Di Marzo and K. Starowicz)]

Current Pharmaceutical Design, 2008
Vincenzo Marzo, Katarzyna Starowicz
openaire   +1 more source

A cooperative knock-on mechanism underpins Ca2+-selective cation permeation in TRPV channels

Journal of General Physiology, 2023
Callum M Ives, Neil Thomson, Ulrich Zachariae   +2 more
exaly  

Blockade of TRPV channels by intracellular spermine

Journal of General Physiology, 2023
Grigory Maksaev, Peng Yuan, Colin G Nichols   +2 more
exaly  

Calcium binding and permeation in TRPV channels: Insights from molecular dynamics simulations

Journal of General Physiology, 2023
Chunhong Liu, Lingfeng Xue, Chen Song
exaly  

Structural insights into the gating mechanisms of TRPV channels

Cell Calcium, 2020
Ruth A Pumroy, Edwin C Fluck, Tofayel Ahmed   +2 more
exaly  

New Potential Therapies from Vanilloid Transient Receptor Cation (TRPV) Channels.

Current pharmaceutical design, 2008
Di Marzo V, Starowicz K
openaire   +3 more sources

Role of the TRPV Channels in the Endoplasmic Reticulum Calcium Homeostasis

Cells, 2020
V'yacheslav Lehen'kyi
exaly