Results 51 to 60 of about 3,404 (180)
In Vitro Evaluation of Arylsulfonamide Derivatives against Trypanosoma cruzi
Drugs and Drug Candidates, 2023 Chagas disease is caused by the parasite protozoan Trypanosoma cruzi (T. cruzi) and affects millions of people in over 21 countries in around the world.
Policarpo Ademar Sales Junior +2 more
doaj +1 more source
Trypanocidal activity of methanol extracts of the hemolymph of Sarcophaga argyrostoma larva against Trypanosoma evansi infected mice [PDF]
Veterinary World, 2020 Background and Aim: Many natural products worldwide are used for medicinal purposes. Various insect-isolated compounds were investigated in pursuit of new therapeutic agents.
Doaa S. Farghaly, Al-Shaimaa M. Sadek
doaj +1 more source
Cutaneous reactions during treatment with Nifurtimox or Benznidazole among Trypanosoma cruzi seropositive adults without symptomatic cardiomyopathy: A safety sub analysis of a placebo-controlled randomised trial. [PDF]
Trop Med Int HealthAbstract Objectives To determine, in a randomised placebo‐controlled trial, if cutaneous adverse reactions during treatment (CARDT) with Benznidazole occur as often as with Nifurtimox, and whether the dose and duration of treatment change that frequency.
Villar JC +7 more
europepmc +2 more sources
Trypanosoma cruzi: analysis of two different strains after piplartine treatment
Brazilian Journal of Infectious Diseases, 2018 The hemoflagellate protozoan, Trypanosoma cruzi, mainly transmitted by triatomine insects through blood transfusion or from mother-to-child, causes Chagas' disease.
Gabriela Alves Licursi Vieira +7 more
doaj +3 more sources
Molecules, 2022 A method was developed for the rapid and quantitative analysis of 30 veterinary drugs belonging to 17 classes (amphenicols (1), anthelmintics (1), cephalosporins (4), coccidiostats (1), lincosamides (1), macrolide (1), nitroimidazole (1), penicillins (3),
Sunyeong Jang +8 more
doaj +1 more source
Pharmaceuticals, 2021 The neglected infection known as Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, results in more than 7000 deaths per year, with an increasing number of cases in non-endemic areas such as Europe or the United States.
Carlos J. Bethencourt-Estrella +8 more
doaj +1 more source
Equine trypanosomiasis, a systematic review and meta‐analyses: Prevalence, morbidity and mortality
Equine Veterinary Journal, EarlyView.Abstract Background Equine trypanosomiasis is a neglected protozoal disease. Objectives To perform a systematic search of literature to explore: (1) In equines what is the global geographical distribution and prevalence of trypanosomiasis? In low and middle‐income countries (LMICs) is trypanosomiasis more prevalent than in higher‐income countries (HICs)
Alexandra G. Raftery +5 more
wiley +1 more source
Anti-Trypanosomal Activity of Nigerian Plants and Their Constituents
Molecules, 2015 African trypanosomiasis is a vector-borne parasitic disease causing serious risks to the lives of about 60 million people and 48 million cattle globally.
Ngozi Justina Nwodo +4 more
doaj +1 more source
ChemMedChem, Volume 21, Issue 1, January 2026.Hypofuran B, drynaran, and a series of analogs are obtined by crossed aldol condensation from furfural dereivatives. Compunds are tested for in vitro activity agaisnt Trypanosoma cruzi and Plasmodium falciparum. Best results are obtained Against P. falciparum, with IC50 values ranging from 5,35 to 10,35 µg mL−1.
Cristiane Aparecida Franco +11 more
wiley +1 more source
Journal of Natural ProductsThe present review article recapitulates for the first time the antipathogenic biological data of a series of lipidic natural products and synthetic analogues thereof characterized by the presence in their structure of an alkynylcarbinol unit. The cytotoxic properties of such natural and bioinspired compounds have been covered by several literature ...
J P Bouvet +4 more
openalex +4 more sources