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Molecular detection of Trypanosoma species in sheep and goats in Mosul city [PDF]
In this study, we examined blood samples of 385 sheep and goats of different ages, sexes, and sources under routine microscopic examination of the blood smear (wet, thin, thick, buffy coat layer smears) to detect Trypanosoma. Results show that 81 samples
Marwa S. Mahmood, Wasan A. Alobaidii
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Proximity labelling is a powerful and rapidly developing technology for exploring the interaction space and molecular environment of a protein of interest at the nanometre scale.
Vincent Geoghegan +2 more
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Trypanosoma cruzi is the etiological agent of American trypanosomiasis, or Chagas disease, and is transmitted mainly by blood-sucking reduviid insects in endemic countries. Metacyclic trypomastigotes released in the feces during the insect blood meal enter a mammalian host through skin wounds or mucosal membranes and invade sur- rounding cells.
Moretti, Nilmar Silvio UNIFESP +2 more
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Chagas Cardiomyopathy: From Romaña Sign to Heart Failure and Sudden Cardiac Death
Despite nearly a century of research and accounting for the highest disease burden of any parasitic disease in the Western Hemisphere, Chagas disease (CD) is still a challenging diagnosis, primarily due to its poor recognition outside of Latin America ...
Antonia Pino-Marín +9 more
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Detection of Blood Parasites in Fish
Fish are often infected with different blood protozoa of the genera Babesiosoma, Trypanosoma, and Hemogrigarina. These blood parasites match the genera which infect the blood of mammals.
Nadia Sultan Alhayali +2 more
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Frequency and diversity of trypanosomes in sheep and goats from Mongo County in South Gabon, Central Africa [PDF]
Background and Aim: Trypanosomosis is a major impediment to livestock farming in sub-Saharan Africa. It is a vector-borne disease caused by several species of protozoan parasites, namely, trypanosomes. The present study aimed to identify the diversity of
Gael Darren Maganga +6 more
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African trypanosomes evade host immune clearance by antigenic variation, causing persistent infections in humans and animals. These parasites express a homogeneous surface coat of variant surface glycoproteins (VSGs).
Abdoulie O Touray +6 more
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Regulation of gene expression in trypanosomatids: living with polycistronic transcription [PDF]
In trypanosomes, RNA polymerase II transcription is polycistronic and individual mRNAs are excised by trans-splicing and polyadenylation. The lack of individual gene transcription control is compensated by control of mRNA processing, translation and ...
Christine Clayton
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Novel Trypanocidal Inhibitors that Block Glycosome Biogenesis by Targeting PEX3–PEX19 Interaction
Human pathogenic trypanosomatid parasites harbor a unique form of peroxisomes termed glycosomes that are essential for parasite viability. We and others previously identified and characterized the essential Trypanosoma brucei ortholog TbPEX3, which is ...
Mengqiao Li +11 more
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Phosphoglycerate kinase: structural aspects and functions, with special emphasis on the enzyme from Kinetoplastea [PDF]
Phosphoglycerate kinase (PGK) is a glycolytic enzyme that is well conserved among the three domains of life. PGK is usually a monomeric enzyme of about 45 kDa that catalyses one of the two ATP-producing reactions in the glycolytic pathway, through the ...
Maura Rojas-Pirela +7 more
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