Population genetics of trypanosoma brucei rhodesiense: clonality and diversity within and between foci [PDF]
African trypanosomes are unusual among pathogenic protozoa in that they can undergo their complete morphological life cycle in the tsetse fly vector with mating as a non-obligatory part of this development.
A MacLeod+70 more
core +26 more sources
Molecular Identification of ABC2 Transporter Gene Encode Protein Ngawi Trypanosoma evansi Isolate that suspected resistance to Isometamidium Chloride [PDF]
This study aims to determine the profile of the ABC2 encoding transporter on Trypanosoma evansi (T. evansi) Ngawi isolates, Indonesia, exposed with Isometamidium Chloride (ISM). This study used blood samples of mice containing Trypanosoma evansi that had
Wusahaningtyas Lu’lu’ Sahara+4 more
doaj +1 more source
While both human and animal trypanosomiasis continue to present as major human and animal public health constraints globally, detailed analyses of trypanosome wildlife reservoir hosts remain sparse.
Keneth Iceland Kasozi+23 more
doaj +1 more source
Therapeutic Strategies against Leishmania and Trypanosoma
Human African trypanosomiasis (also known as sleeping sickness, with Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense as etiological agents), American trypanosomiasis (also known as Chagas disease, with Trypanosoma cruzi as the etiological
André L. S. Santos+5 more
doaj +1 more source
Ribose 5-phosphate isomerase B knockdown compromises Trypanosoma brucei bloodstream form infectivity. [PDF]
Ribose 5-phosphate isomerase is an enzyme involved in the non-oxidative branch of the pentose phosphate pathway, and catalyzes the inter-conversion of D-ribose 5-phosphate and D-ribulose 5-phosphate.
Inês Loureiro+7 more
doaj +1 more source
Molecular variation of Trypanosoma brucei subspecies as revealed by AFLP fingerprinting [PDF]
Genetic analysis of Trypanosoma spp. depends on the detection of variation between strains. We have used the amplified fragment length polymorphism (AFLP) technique to develop a convenient and reliable method for genetic characterization of Trypanosome ...
Agbo, E.E.C.+3 more
core +10 more sources
This study investigated the antitrypanosomal activity of Argemone mexicana extract and fractions in the animal model of Trypanosoma brucei brucei infection.
Chukwu Ifeoma L.+5 more
doaj +1 more source
Wild chimpanzees are infected by Trypanosoma brucei
Although wild chimpanzees and other African great apes live in regions endemic for African sleeping sickness, very little is known about their trypanosome infections, mainly due to major difficulties in obtaining their blood samples.
Milan Jirků+13 more
doaj +1 more source
African Trypanosomes undermine humoral responses and vaccine development : link with inflammatory responses? [PDF]
African trypanosomosis is a debilitating disease of great medical and socioeconomical importance. It is caused by strictly extracellular protozoan parasites capable of infecting all vertebrate classes including human, livestock, and game animals.
Achcar+160 more
core +1 more source
Activation of endocytosis as an adaptation to the mammalian host by trypanosomes [PDF]
Immune evasion in African trypanosomes is principally mediated by antigenic variation, but rapid internalization of surface-bound immune factors may contribute to survival.
Field, Mark C+4 more
core +2 more sources