Results 121 to 130 of about 102,275 (301)
N‐Glycoproteomics of the Apicomplexan Parasite Toxoplasma gondii
PROTEOMICS, Volume 25, Issue 8, April 2025.ABSTRACT Protein N‐glycosylation influences protein folding, stability, and trafficking, and has prominent functions in cell–cell adhesion and recognition. For the parasite Toxoplasma gondii, N‐glycosylation of proteins is crucial for initial adhesion to host cells, parasite motility, and consequently, its ability to invade host cells.
Vanessa Horn +5 more
wiley +1 more source
Nucleic Acids Research, 2014 While gene expression is a fundamental and tightly controlled cellular process that is regulated at multiple steps, the exact contribution of each step remains unknown in any organism. The absence of transcription initiation regulation for RNA polymerase
Juan-José Vasquez +4 more
semanticscholar +1 more source
C-terminal mutants of apolipoprotein L-I efficiently kill both Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense. [PDF]
PLoS Pathogens, 2009 Apolipoprotein L-I (apoL1) is a human-specific serum protein that kills Trypanosoma brucei through ionic pore formation in endosomal membranes of the parasite. The T.
Laurence Lecordier +7 more
doaj +1 more source
The FEBS Journal, Volume 292, Issue 8, Page 1868-1883, April 2025.Traditionally, adipocytes have been viewed as energy storage units, which upregulate inflammatory factors in response to obesity. However, emerging evidence demonstrates that adipocytes are highly responsive to systemic infection, and upregulate cytokines and antimicrobial compounds in response.
Matthew C. Sinton, Shingo Kajimura
wiley +1 more source
Structure of thioredoxin from Trypanosoma brucei brucei
FEBS Letters, 2003 The three‐dimensional structure of thioredoxin from Trypanosoma brucei brucei has been determined at 1.4 Å resolution. The overall structure is more similar to that of human thioredoxin than to any other thioredoxin structure. The most striking difference to other thioredoxins is the absence of a buried carboxylate behind the active site cysteines ...
Heide Schmidt +5 more
openaire +3 more sources
, 2016 The nucleus is arguably the defining characteristic of eukaryotes, distinguishing their cell organisation from both bacteria and archaea. Though the evolutionary history of the nucleus remains the subject of debate, its emergence differs from several ...
McCulloch, Richard, Navarro, Miguel
core +1 more source
Synthesis of biotinylated probes of artemisinin for affinity labeling
Data in Brief, 2015 In this data article, we described the synthetic routes to four biotinylated probes (2, 3, 4, and 5) of artemisinin and the associated experimental procedures. We also provided the physical data for the synthesized compounds.
Benetode Konziase
doaj +1 more source
Advanced Science, Volume 12, Issue 11, March 20, 2025.This study reveals that Zbp1 plays a pivotal role in regulating neuroimmune interactions during Angiostrongylus cantonensis (AC) infection. Zbp1 modulates lymphocyte infiltration and natural killer (NK) cell cytotoxicity by promoting cytokine secretion and M1 polarization of macrophages, shaping the CNS immune microenvironment.
Hongli Zhou +10 more
wiley +1 more source
Journal of Proteome Research, 2014 The glycosome of the pathogenic African trypanosome Trypanosoma brucei is a specialized peroxisome that contains most of the enzymes of glycolysis and several other metabolic and catabolic pathways.
M. L. Güther +4 more
semanticscholar +1 more source
Characterization of Trypanosoma brucei gambiense variant surface glycoprotein LiTat 1.5 [PDF]
, 2012 At present, all available diagnostic antibody detection tests for Trypanosoma brucei gambiense human African trypanosomiasis are based on predominant variant surface glycoproteins (VSGs), such as VSG LiTat 1.5. During investigations aiming at replacement
Büscher, P. +4 more
core +1 more source