Results 131 to 140 of about 102,275 (301)
Trypanosoma brucei infection protects mice against malaria.
PLoS Pathogens, 2019 Sleeping sickness and malaria are parasitic diseases with overlapping geographical distributions in sub-Saharan Africa. We hypothesized that the immune response elicited by an infection with Trypanosoma brucei, the etiological agent of sleeping sickness,
Margarida Sanches-Vaz +8 more
doaj +1 more source
Onderstepoort Journal of Veterinary Research, 2004 The protective efficacy of isometamidium chloride (ISMM) and diminazene aceturate (DIM) against Trypanosoma brucei, Trypanosoma congolense and Trypanosoma vivax infections in cattle under a suppressed tsetse population was assessed in southeast Uganda.
J.W. Magona +3 more
doaj +1 more source
Flavin‐Dependent Nitroreductases: Privileged Enzymes for Chemical and Photochemical Synthesis
ChemCatChem, Volume 17, Issue 5, March 6, 2025.This review summarizes the functional, structural, and mechanistic properties of flavin‐dependent nitroreductases and highlights their usefulness for the synthesis of nitrogen‐containing compounds. Recent advances in enzyme and cofactor engineering, as well as in the use of nitroreductases in photobiocatalytic approaches, are emphasized.
Sara Russo +3 more
wiley +1 more source
Nucleic Acids Research, 2014 Base J, β-d-glucosyl-hydroxymethyluracil, is an epigenetic modification of thymine in the nuclear DNA of flagellated protozoa of the order Kinetoplastida. J is enriched at sites involved in RNA polymerase (RNAP) II initiation and termination.
D. Reynolds +5 more
semanticscholar +1 more source
On the extent and role of the small proteome in the parasitic eukaryote Trypanosoma brucei [PDF]
, 2014 Background: Although technical advances in genomics and proteomics research have yielded a better understanding of the coding capacity of a genome, one major challenge remaining is the identification of all expressed proteins, especially those less than ...
Butter, F. +5 more
core +1 more source
Microbiology Research, 2017 The plant Pomegranate (Punica granatum Linn.) selected for this study is native to the region of Eurasia. The objective of this study was to evaluate the antitrypanosomal potential of the plant against Trypanosoma brucei brucei (T.b.
Muhammad Muhsin Fathuddin +1 more
doaj +1 more source
Holistic Investigation of Graphene Quantum Dot Endocytosis
Small, Volume 21, Issue 9, March 5, 2025.Six chemical endocytosis inhibitors are used to selectively block and analyze preferential uptake pathways of Graphene Quantum Dots (GQDs) in cancerous (HeLa) versus non‐cancerous (HEK‐293) cells via fluorescence microscopy. Contrary to previously perceived singular mechanism for GQD endocytosis, this work suggests that GQDs prefer a combination of ...
Ugur C. Topkiran +10 more
wiley +1 more source
Tracking autophagy during proliferation and differentiation of trypanosoma brucei [PDF]
, 2014 Autophagy is a lysosome-dependent degradation mechanism that sequesters target cargo into autophagosomal vesicles. The Trypanosoma brucei genome contains apparent orthologues of several autophagy-related proteins including an ATG8 family. These ubiquitin-
Coombs, Graham H. +3 more
core +3 more sources
Scientific ReportsAnimal African trypanosomiasis (AAT) is a significant food security and economic burden in sub-Saharan Africa. Current AAT empirical and immunodiagnostic surveillance tools suffer from poor sensitivity and specificity, with blood sampling requiring ...
Isabel Saldanha +10 more
doaj +1 more source
Multiple evolutionary origins of Trypanosoma evansi in Kenya.
PLoS Neglected Tropical Diseases, 2017 Trypanosoma evansi is the parasite causing surra, a form of trypanosomiasis in camels and other livestock, and a serious economic burden in Kenya and many other parts of the world.
Christine M Kamidi +8 more
doaj +1 more source