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Malleable Mitochondrion of Trypanosoma brucei

2015
The importance of mitochondria for a typical aerobic eukaryotic cell is undeniable, as the list of necessary mitochondrial processes is steadily growing. Here, we summarize the current knowledge of mitochondrial biology of an early-branching parasitic protist, Trypanosoma brucei, a causative agent of serious human and cattle diseases.
Zdeněk, Verner   +15 more
openaire   +2 more sources

Tubulin mRNAs of Trypanosoma brucei

Journal of Molecular Biology, 1986
The tubulin genes of Trypanosoma brucei are located in a single, tightly packed cluster of ten tandemly arranged alternating alpha and beta-genes. No tubulin genes are detected outside the clustered array. Therefore, the cluster can be assumed to be the locus of tubulin gene expression.
M, Imboden   +4 more
openaire   +2 more sources

MicroRNA switches in Trypanosoma brucei

Biochemical and Biophysical Research Communications, 2008
Trypanosoma brucei develops chronic infection in mammalian hosts due to a sophisticated strategy of antigenic variation of variant surface glycoprotein (VSG) coat to escape antibody-mediated lysis. MicroRNAs are a class of non-coding RNAs with presumed post-transcriptional regulatory activity.
Bibekanand, Mallick   +2 more
openaire   +2 more sources

Trypanosoma brucei and the nervous system

Trends in Neurosciences, 1994
African sleeping sickness, characterized by a peculiar pain syndrome and prominent neuropsychiatric symptoms, is caused by the parasite Trypanosoma brucei (T.b.). In experimental T.b. infections, a molecule released from the trypanosomes has been isolated that binds to the CD8 molecule of T cells, whereby T cells are activated to secrete interferon ...
Bentivoglio M.   +3 more
openaire   +2 more sources

Cultivation of Dyskinetoplastic Trypanosoma brucei

The Journal of Parasitology, 1980
Dyskinetoplastic (Dk) mutant African trypanosomes are able to grow in the mammalian host, but not in the insect host or in culture media in which normal African trypanosomes grow as procyclic trypomastigotes (midgut forms). This inability of Dk mutants to grow as procyclic trypomastigotes is the result of alterations of the kinetoplast (mitochondrial ...
openaire   +2 more sources

Protein isoprenylation in Trypanosoma brucei brucei

Biochemical Society Transactions, 1996
H, Field   +3 more
openaire   +2 more sources

Uptake of α-difluoromethylornithine by Trypanosoma brucei brucei

Biochemical Pharmacology, 1986
A J, Bitonti   +3 more
openaire   +2 more sources

Silencing of the thioredoxin gene in Trypanosoma brucei brucei

Molecular and Biochemical Parasitology, 2002
Armin, Schmidt   +2 more
openaire   +2 more sources

Acidocalcisome Is Required for Autophagy in Trypanosoma brucei

Autophagy, 2014
Cynthia Y He, Feng-Jun Li
exaly  

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