Results 1 to 10 of about 50,586 (204)

Development of a camelid single-domain antibody-based antigen detection assay for the pan-specific diagnosis of active human and animal Trypanosoma brucei infections [PDF]

Journal of Clinical Microbiology
Trypanosoma brucei infections cause African trypanosomiasis, also known as sleeping sickness in humans and nagana in animals, presenting a significant global health and economic burden, especially in sub-Saharan Africa.
Zeng Li, Bo-kyung Jin, Emily Estefania Timaury Moreno, Andrés Álvarez-Rodríguez, Jo A. Van Ginderachter, Magdalena Radwanska, Yann G. -J. Sterckx, Benoit Stijlemans, Stefan Magez   +8 more
doaj   +2 more sources

Route of inoculation influences Trypanosoma congolense and Trypanosoma brucei brucei virulence in Swiss white mice. [PDF]

PLoS ONE, 2019
Experiments on infections caused by trypanosomes are widely performed in Swiss white mice through various inoculation routes. To better understand the effect of route of trypanosome inoculation on disease outcomes in this model, we characterised the ...
Kariuki Ndungu, Daniel Thungu, Florence Wamwiri, Paul Mireji, Geoffrey Ngae, Purity Gitonga, James Mulinge, Joanna Auma, John Thuita   +8 more
doaj   +2 more sources

Population genetics of trypanosoma brucei rhodesiense: clonality and diversity within and between foci [PDF]

, 2013
African trypanosomes are unusual among pathogenic protozoa in that they can undergo their complete morphological life cycle in the tsetse fly vector with mating as a non-obligatory part of this development.
A MacLeod, A MacLeod, A MacLeod, A Tait, A Tait, A Tait, A Tait, Andy Tait, Anneli Cooper, Annette MacLeod, BG Spratt, C. Michael R. Turner, CA Oura, Craig W. Duffy, CW Duffy, Daniel K. Masiga, DK Howe, EM Fevre, EM Fevre, F Balloux, F Mathieu-Daude, F Njiokou, FG Razakandrainibe, G Hide, G Hide, G Hide, HK Auty, HV Xong, J Maynard Smith, J Sternberg, Jeremy Sternberg, JJ McNamara, JR Stevens, L Berrang-Ford, L Jenni, L MacLean, L MacLean, L Peacock, L Peacock, Liam J. Morrison, Lindsay Sweeney, LJ Morrison, LJ Morrison, LJ Morrison, LJ Morrison, LM MacLean, Lorna MacLean, M Koffi, M Koffi, M Tibayrenc, M Tibayrenc, M Tibayrenc, NE Anderson, O Balmer, P Paindavoine, R Peakall, RD Page, RE Paul, RJ Pearce, SC Welburn, TJ Anderson, V Jamonneau, W Gibson, W Gibson, W Gibson, W Gibson, W Gibson, W Weir, WC Gibson, WC Gibson, Z Annan   +70 more
core   +30 more sources

Molecular Identification of ABC2 Transporter Gene Encode Protein Ngawi Trypanosoma evansi Isolate that suspected resistance to Isometamidium Chloride [PDF]

BIO Web of Conferences, 2021
This study aims to determine the profile of the ABC2 encoding transporter on Trypanosoma evansi (T. evansi) Ngawi isolates, Indonesia, exposed with Isometamidium Chloride (ISM). This study used blood samples of mice containing Trypanosoma evansi that had
Wusahaningtyas Lu’lu’ Sahara, Nuryady Moh Mirza, Firdausy Lintang Winantya, Fahrurrozi Zs Ahmad, Nurcahyo R. Wisnu   +4 more
doaj   +1 more source

Visualisation of experimentally determined and predicted protein N-glycosylation and predicted glycosylphosphatidylinositol anchor addition in Trypanosoma brucei. [version 1; peer review: 3 approved]

Wellcome Open Research, 2022
Background: Trypanosoma brucei is a protozoan parasite and the etiological agent of human and animal African trypanosomiasis. The organism cycles between its mammalian host and tsetse vector.
Michael A. J. Ferguson, Michele Tinti
doaj   +1 more source

Trypanosoma brucei brucei is more pathogenic in rats compared to mice, making rats a better candidate for the relevant research studies [PDF]

The Iranian Journal of Veterinary Science and Technology, 2021
Trypanosomosis is an economically important disease that has raised great and diverse kinds of research using different types of animals. Hence, this study is aimed at determining the better laboratory animal between the Swiss albino mice and Wistar ...
Karimat Hussain, Shola Ola-Fadunsin, Idris Lawal, Sani Adamu, Saliu Ameen   +4 more
doaj   +1 more source

Molecular identification of Trypanosoma brucei brucei and in vitro anti-trypanosomal activity of different parts of methanolic extract of Senna occidentalis

Clinical Phytoscience, 2020
Objective The present study investigated the anti-Trypanosoma brucei brucei activity of methanolic extract of Senna occidentalis roots, leaves, stem bark, and seed in vitro and bioactive components of the most active plant part.
Zainab Aliyu Alhafiz, Mohammed Sani Abdulsalami, Mohammed Auwal Ibrahim, Timothy Bulus, Ahmed Babangida Suleiman   +4 more
doaj   +1 more source

Therapeutic Strategies against Leishmania and Trypanosoma

Pathogens, 2023
Human African trypanosomiasis (also known as sleeping sickness, with Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense as etiological agents), American trypanosomiasis (also known as Chagas disease, with Trypanosoma cruzi as the etiological
André L. S. Santos, Igor A. Rodrigues, Claudia M. d’Avila-Levy, Cátia L. Sodré, Koert Ritmeijer, Marta H. Branquinha   +5 more
doaj   +1 more source

Golgi-associated phosphohydrolases in Trypanosoma brucei brucei

Molecular and Biochemical Parasitology, 1997
Various parasitic protozoa of the family Trypanosomatidae such as Crithidia spp. [1]; Trypanosoma cruzi [2]; Leishmania donovani [3] and salivarian trypanosomes [4-8] have been shown to contain acid phosphatase activity (EC.3.1.3.2, orthophosphoric-monoester phosphohydrolase activity).
Grab, D.J., Webster, P., Verjee, Y., Lonsdale-Eccles, J.   +3 more
openaire   +4 more sources

Antitrypanosomal activity of Argemone mexicana extract and fractions in the animal model of Trypanosoma brucei brucei infection

Open Veterinary Science, 2022
This study investigated the antitrypanosomal activity of Argemone mexicana extract and fractions in the animal model of Trypanosoma brucei brucei infection.
Chukwu Ifeoma L., Ugwu Malachy C., Iroha Ifeanyi R., Mbagwu Ikechukwu S., Okafor Ugochukwu U., Ajaghaku Amara A.   +5 more
doaj   +1 more source