Results 1 to 10 of about 68,686 (295)
The exosome of Trypanosoma brucei [PDF]
The EMBO Journal, 2001 The yeast exosome is a complex of at least 10 essential 3'-5' riboexonucleases which is involved in 3'-processing of many RNA species. An exosome-like complex has been found or predicted to exist in other eukaryotes but not in Escherichia coli. The unicellular parasite Trypanosoma brucei diverged very early in eukaryotic evolution.
Antonio M. Estévez +2 more
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Signatures of hybridization in Trypanosoma brucei [PDF]
PLOS Pathogens, 2022 Genetic exchange among disease-causing micro-organisms can generate progeny that combine different pathogenic traits. Though sexual reproduction has been described in trypanosomes, its impact on the epidemiology of Human African Trypanosomiasis (HAT) remains controversial.
Christopher Kay +3 more
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Transport of -Aminoisobutyrate into Trypanosoma brucei brucei [PDF]
Microbiology, 1984 The uptake of alpha-aminoisobutyrate (AIB) by washed cell suspensions of bloodstream forms of Trypanosoma brucei brucei has been shown to be an energy-dependent process. No metabolism of AIB was detected under conditions leading to a 100-fold accumulation of AIB within the organism. Kinetic studies revealed that AIB uptake involved two components; that
K. P. Coolbear, M. Midgley
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The exopolyphosphatase TbrPPX1 of Trypanosoma brucei [PDF]
BMC Microbiology, 2011 Abstract Background Exopolyphosphatases and pyrophosphatases play important but still incompletely understood roles in energy metabolism, and also in other aspects of cell biology such as osmoregulation or signal transduction.
Luginbuehl, Edith +4 more
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On The Cultivation Of Trypanosoma Brucei [PDF]
Journal of Infectious Diseases, 1904 n ...
Novy, F. G., McNeal, W. J.
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Characterization of an endopeptidase of Trypanosoma brucei brucei
Archives of Biochemistry and Biophysics, 1992 A soluble 80-kDa endopeptidase has been isolated from Trypanosoma brucei brucei. The enzyme, which has a pI 5.1, is optimally active at about pH 8.2 and has apparent pKa values of 6.0 and greater than or equal to 10. It is inhibited by the serine protease inhibitor diisopropylfluorophosphate and by the serine protease mechanism-based inhibitor 3,4 ...
Kornblatt, M.J. +2 more
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SUMOylation inTrypanosoma brucei
PeerJ, 2013 Small ubiquitin like modifier (SUMO) proteins are involved in many processes in eukaryotes. We here show that Trypanosoma brucei SUMO (Tb927.5.3210) modifies many proteins. The levels of SUMOylation were unaffected by temperature changes but were increased by severe oxidative stress.
Dorothea Droll +2 more
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The lysis of Trypanosoma brucei brucei by human serum [PDF]
Nature Biotechnology, 1996 The natural immunity of humans to the cattle pathogen Trypanosoma brucei brucei, but not to the morphologically indistinguishable human pathogens T. brucei gambiense and T. brucei rhodesiense, is due to the selective killing of the parasite by normal human serum. The factor in human serum that mediates lysis of T. brucei brucei has long been attributed
Stephen Tomlinson, Jayne Raper
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The nuclear proteome of Trypanosoma brucei [PDF]
PLOS ONE, 2017 Trypanosoma brucei is a protozoan flagellate that is transmitted by tsetse flies into the mammalian bloodstream. The parasite has a huge impact on human health both directly by causing African sleeping sickness and indirectly, by infecting domestic cattle. The biology of trypanosomes involves some highly unusual, nuclear-localised processes.
Carina Goos +4 more
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Lipid metabolism in Trypanosoma brucei [PDF]
Molecular and Biochemical Parasitology, 2010 Trypanosoma brucei membranes consist of all major eukaryotic glycerophospholipid and sphingolipid classes. These are de novo synthesized from precursors obtained either from the host or from catabolised endocytosed lipids. In recent years, substantial progress has been made in the molecular and biochemical characterisation of several of these lipid ...
Smith Terry K, Bütikofer Peter
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