Results 121 to 130 of about 68,686 (295)
Response of Trypanosoma brucei brucei-induced anaemia to a commercial herbal preparation
, 2003 ®is a herbal preparation made from three medicinal herbs (Parquetina nigrescens, Sorghum bicolor and Harungana madagascariensis). It has been reported to have been successfully used in the treatment of anaemia in humans. A study was therefore carried out
P. Erah, C. Asonye, A. O. Okhamafe
semanticscholar +1 more source
Journal of Experimental Medicine, 1996 Natural immunity of humans to the cattle pathogen Trypanosoma brucei brucei has been attributed to the presence in normal human serum (NHS) of lytic factors for the parasites.
J. Raper, V. Nussenzweig, S. Tomlinson
semanticscholar +1 more source
Tracking autophagy during proliferation and differentiation of trypanosoma brucei [PDF]
, 2014 Autophagy is a lysosome-dependent degradation mechanism that sequesters target cargo into autophagosomal vesicles. The Trypanosoma brucei genome contains apparent orthologues of several autophagy-related proteins including an ATG8 family. These ubiquitin-
Coombs, Graham H. +3 more
core +3 more sources
Holistic Investigation of Graphene Quantum Dot Endocytosis
Small, Volume 21, Issue 9, March 5, 2025.Six chemical endocytosis inhibitors are used to selectively block and analyze preferential uptake pathways of Graphene Quantum Dots (GQDs) in cancerous (HeLa) versus non‐cancerous (HEK‐293) cells via fluorescence microscopy. Contrary to previously perceived singular mechanism for GQD endocytosis, this work suggests that GQDs prefer a combination of ...
Ugur C. Topkiran +10 more
wiley +1 more source
Trypanosoma brucei infection protects mice against malaria.
PLoS Pathogens, 2019 Sleeping sickness and malaria are parasitic diseases with overlapping geographical distributions in sub-Saharan Africa. We hypothesized that the immune response elicited by an infection with Trypanosoma brucei, the etiological agent of sleeping sickness,
Margarida Sanches-Vaz +8 more
doaj +1 more source
Biochemical Journal, 1991 We reported recently that administration of ([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine (MDL 73811), an enzyme-activated irreversible inhibitor of S-adenosyl-L-methionine decarboxylase (AdoMetDC; EC 4.1.1.50), a key enzyme in the synthesis of ...
T. Byers, T. Bush, P. McCann, A. Bitonti
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 1997 Mice infected with the protozoan parasite Trypanosoma brucei brucei and treated subcuratively with the trypanocidal drug diminazene aceturate develop an acute inflammatory meningoencephalitis with associated astrocytic proliferation.
P. Kennedy +5 more
semanticscholar +1 more source
Characterization of Trypanosoma brucei gambiense variant surface glycoprotein LiTat 1.5 [PDF]
, 2012 At present, all available diagnostic antibody detection tests for Trypanosoma brucei gambiense human African trypanosomiasis are based on predominant variant surface glycoproteins (VSGs), such as VSG LiTat 1.5. During investigations aiming at replacement
Büscher, P. +4 more
core +1 more source
Performance of diagnostic tests for Trypanosoma brucei brucei in experimentally infected pigs. [PDF]
PLoS Negl Trop Dis, 2023 Ilboudo K +10 more
europepmc +1 more source
The ever unfolding story of cAMP signaling in trypanosomatids: vive la difference! [PDF]
, 2015 Kinetoplastids are unicellular, eukaryotic, flagellated protozoans containing the eponymous kinetoplast. Within this order, the family of trypanosomatids are responsible for some of the most serious human diseases, including Chagas disease (Trypanosoma ...
De Koning, Harry P. +2 more
core +1 more source