Results 41 to 50 of about 69,743 (296)
Phosphorylation-dependent protein interaction with Trypanosoma brucei 14-3-3 proteins that display atypical target recognition. [PDF]
PLoS ONE, 2010 BACKGROUND: The 14-3-3 proteins are structurally conserved throughout eukaryotes and participate in protein kinase signaling. All 14-3-3 proteins are known to bind to evolutionally conserved phosphoserine-containing motifs (modes 1 and/or 2) with high ...
Masahiro Inoue +7 more
doaj +1 more source
Characterization of Trypanosoma brucei gambiense variant surface glycoprotein LiTat 1.5 [PDF]
, 2012 At present, all available diagnostic antibody detection tests for Trypanosoma brucei gambiense human African trypanosomiasis are based on predominant variant surface glycoproteins (VSGs), such as VSG LiTat 1.5. During investigations aiming at replacement
Büscher, P. +4 more
core +1 more source
Evidence for regulated expression of Telomeric Repeat-containing RNAs (TERRA) in parasitic trypanosomatids [PDF]
, 2017 The Telomeric Repeat-containing RNAs (TERRA) participate in the homeostasis of telomeres in higher eukaryotes. Here, we investigated the expression of TERRA in Leishmania spp.
Damasceno, Jeziel D. +3 more
core +1 more source
SUMOylation inTrypanosoma brucei
PeerJ, 2013 Small ubiquitin like modifier (SUMO) proteins are involved in many processes in eukaryotes. We here show that Trypanosoma brucei SUMO (Tb927.5.3210) modifies many proteins. The levels of SUMOylation were unaffected by temperature changes but were increased by severe oxidative stress.
Dorothea Droll +2 more
openaire +4 more sources
Parasites & Vectors, 2014 Background Human African Trypanosomiasis is still a public health threat in Cameroon. To assess Trypanosoma brucei strains circulating in the Fontem sleeping sickness focus, we conducted a genetic structure study using microsatellites to assess genotypes
Gustave Simo +5 more
doaj +1 more source
P-type transport ATPases in Leishmania and Trypanosoma
Parasite, 2019 P-type ATPases are critical to the maintenance and regulation of cellular ion homeostasis and membrane lipid asymmetry due to their ability to move ions and phospholipids against a concentration gradient by utilizing the energy of ATP hydrolysis.
Meade John C.
doaj +1 more source
Beni-Suef University Journal of Basic and Applied Sciences, 2021 Background Euphorbia is the largest genus in family Euphorbiaceae with a great biological and genetic diversity. The anti-trypanosomal activity of the crude extract of 15 Euphorbia species against Trypanosoma brucei brucei was carried out.
Seham S. El-Hawary +4 more
doaj +1 more source
Journal of Biological Chemistry, 1995 The African trypanosome, Trypanosoma brucei brucei, possesses at least two nucleoside transporter systems designated P1 and P2, the latter being implicated in the selective uptake of melaminophenyl arsenical drugs.
N. Carter, B. Berger, A. Fairlamb
semanticscholar +1 more source
Tracking autophagy during proliferation and differentiation of trypanosoma brucei [PDF]
, 2014 Autophagy is a lysosome-dependent degradation mechanism that sequesters target cargo into autophagosomal vesicles. The Trypanosoma brucei genome contains apparent orthologues of several autophagy-related proteins including an ATG8 family. These ubiquitin-
Coombs, Graham H. +3 more
core +3 more sources
The lysis of Trypanosoma brucei brucei by human serum [PDF]
Nature Biotechnology, 1996 The natural immunity of humans to the cattle pathogen Trypanosoma brucei brucei, but not to the morphologically indistinguishable human pathogens T. brucei gambiense and T. brucei rhodesiense, is due to the selective killing of the parasite by normal human serum. The factor in human serum that mediates lysis of T. brucei brucei has long been attributed
Stephen Tomlinson, Jayne Raper
openaire +3 more sources