Results 61 to 70 of about 68,686 (295)

Réponse du poulet nigérian local ( Gallus domesticus) aux trypanosomes

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1988
La réponse du poulet nigérian local aux souches de Trypanosoma brucei 8/18 et T. vivax Y58 a été recherchée. Le poulet local utilisé dans cette étude était sensible à T. brucei mais réfractaire à T. vivax (Y58) (une souche adaptée aux rongeurs).
O.A. Dina, R.O.A. Arowolo
doaj   +1 more source

Design, synthesis, and antiprotozoal evaluation of new 2,4-bis[(substituted-aminomethyl)phenyl]quinoline, 1,3-bis[(substituted-aminomethyl)phenyl]isoquinoline and 2,4-bis[(substituted-aminomethyl)phenyl]quinazoline derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
A series of new 2,4-bis[(substituted-aminomethyl)phenyl]quinoline, 1,3-bis[(substituted-aminomethyl)phenyl]isoquinoline, and 2,4-bis[(substituted-aminomethyl)phenyl]quinazoline derivatives was designed, synthesised, and evaluated in vitro against three ...
Jean Guillon, Anita Cohen, Clotilde Boudot, Alessandra Valle, Vittoria Milano, Rabindra Nath Das, Aurore Guédin, Stéphane Moreau, Luisa Ronga, Solène Savrimoutou, Maxime Demourgues, Elodie Reviriego, Sandra Rubio, Sandie Ferriez, Patrice Agnamey, Cécile Pauc, Serge Moukha, Pascale Dozolme, Sophie Da Nascimento, Pierre Laumaillé, Anne Bouchut, Nadine Azas, Jean-Louis Mergny, Catherine Mullié, Pascal Sonnet, Bertrand Courtioux   +25 more
doaj   +1 more source

Resolving Trypanosoma brucei Flagellar Structure by Cryo-Electron Tomography [PDF]

E3S Web of Conferences, 2019
Trypanosoma brucei is a unicellular eukaryote that can cause human African trypanosomiasis, which has continued to evolve and spread. The key feature of these parasites is that they have a flagellum consists of a typical 9 + 2 axoneme and a lattice-like ...
Dai Jennifer
doaj   +1 more source

Development of an Alamar Blue viability assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.

American Journal of Tropical Medicine and Hygiene, 2009
There is an urgent need for new compounds for the drug development pipeline for treatment of patients with African sleeping sickness. One approach for identifying such compounds is by high throughput screening (HTS) of compound collections.
M. Sykes, V. Avery
semanticscholar   +1 more source

Molecular variation of Trypanosoma brucei subspecies as revealed by AFLP fingerprinting [PDF]

, 2002
Genetic analysis of Trypanosoma spp. depends on the detection of variation between strains. We have used the amplified fragment length polymorphism (AFLP) technique to develop a convenient and reliable method for genetic characterization of Trypanosome ...
Agbo, E.E.C., Claassen, H.J.H.M., Majiwa, P.A.O., Pas, M.F.W., te   +3 more
core   +9 more sources

Measure of Molecular Diversity within the Trypanosoma brucei Subspecies Trypanosoma brucei brucei and Trypanosoma brucei gambiense as Revealed by Genotypic Characterization

Experimental Parasitology, 2001
We have evaluated whether sequence polymorphisms in the rRNA intergenic spacer region can be used to study the relatedness of two subspecies of Trypanosoma brucei. Thirteen T. brucei isolates made up of 6 T. b. brucei and 7 T. b. gambiense were analyzed using restriction fragment length polymorphism (RFLP).
Agbo, E.C., Majiwa, P.A.O., Classsen, E.J.H.M., Roos, M.H.   +3 more
openaire   +4 more sources

Analytical purification of a 60-kDa target protein of artemisinin detected in Trypanosoma brucei brucei

Data in Brief, 2015
Here we describe the isolation and purity determination of Trypanosoma brucei (T. b.) brucei candidate target proteins of artemisinin. The candidate target proteins were detected and purified from their biological source (T. b.
Benetode Konziase
doaj   +1 more source

Kinetic properties of triose-phosphate isomerase from Trypanosoma brucei brucei. A comparison with the rabbit muscle and yeast enzymes.

European Journal of Biochemistry, 1987
The kinetic properties of Trypanosoma brucei brucei triose-phosphate isomerase are compared with those of the commercially available rabbit muscle and yeast enzymes and with published data on the chicken muscle enzyme.
A. Lambeir, Frederik Opperdoes, Rik K. Wierenga   +2 more
semanticscholar   +1 more source

Bloodstream form trypanosoma brucei depend upon multiple metacaspases associated with RAB11-positive endosomes [PDF]

, 2006
Trypanosoma brucei possesses five metacaspase genes. Of these, MCA2 and MCA3 are expressed only in the mammalian bloodstream form of the parasite, whereas MCA5 is expressed also in the insect procyclic form.
Ambit, Audrey, Appleton, Paul, Coombs, Graham H., Helms, Matthew J., Mottram, Jeremy C., Tetley, Laurence   +5 more
core   +1 more source

In vitro Anti-trypanosomal Activity of Ethanolic and n-Hexane Extracts of Hymenocardia acida Stem Bark against Trypanosoma bruceibrucei and Trypanosoma congolense

UMYU Journal of Microbiology Research
Study’s Novelty/Excerpt • The potential of Hymenocardia acida stem bark extracts as an anti-trypanosomal agent was assessed. • The results indicate significant in vitro activity of both ethanolic and n-hexane extracts against Trypanosoma brucei brucei
Lawal, S. M., Inabo, H. I., Ella, E. E., Okubanjo, O. O.   +3 more
doaj   +1 more source