Results 71 to 80 of about 68,686 (295)
Hydroxyurea-induced synchronisation of bloodstream stage Trypanosoma brucei [PDF]
Synchronisation of the <i>Trypanosoma brucei</i> cell cycle proved elusive for many years. A recent report demonstrated that synchronisation of procyclic form cells was possible following treatment with hydroxyurea.
Forsythe, Glynn R.+2 more
core +1 more source
The Antiprotozoal Activity of Papua New Guinea Propolis and Its Triterpenes
Profiling a propolis sample from Papua New Guinea (PNG) using high-resolution mass spectrometry indicated that it contained several triterpenoids. Further fractionation by column chromatography and medium-pressure liquid chromatography (MPLC) followed by
Samya S. Alenezi+10 more
doaj +1 more source
Trypanosoma brucei brucei S-adenosyl-L-methionine (AdoMet) decarboxylase was found to be relatively insensitive to activation by putrescine as compared with the mammalian enzyme, being stimulated by only 50% over a 10,000-fold range of putrescine ...
A. Bitonti, J. Dumont, P. McCann
semanticscholar +1 more source
Golgi-associated phosphohydrolases in Trypanosoma brucei brucei
Various parasitic protozoa of the family Trypanosomatidae such as Crithidia spp. [1]; Trypanosoma cruzi [2]; Leishmania donovani [3] and salivarian trypanosomes [4-8] have been shown to contain acid phosphatase activity (EC.3.1.3.2, orthophosphoric-monoester phosphohydrolase activity).
Grab, D.J.+3 more
openaire +4 more sources
Genetic control of resistance to Trypanosoma brucei brucei infection in mice. [PDF]
BackgroundTrypanosoma brucei brucei infects livestock, with severe effects in horses and dogs. Mouse strains differ greatly in susceptibility to this parasite.
Matyáš Síma+8 more
doaj +1 more source
The cytoskeleton of the parasitic hemoflagellate Trypanosoma brucei brucei essentially consists of two microtubule-based structures: a subpellicular layer of singlet microtubules, which are in close contact with the cell membrane, and the flagellar ...
A. Schneider+5 more
semanticscholar +1 more source
Trypanosoma brucei: meet the system [PDF]
African trypanosomes cause devastating diseases in humans and domestic animals. The parasites evolved early in the eukaryotic lineage and have numerous biochemical peculiarities that distinguish them from other systems. These include unconventional mechanisms for expressing nuclear and mitochondrial genes as well as unusual subcellular localizations ...
Fiona Achcar+2 more
openaire +3 more sources
Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley +1 more source
The developmental cell biology of Trypanosoma brucei [PDF]
Trypanosoma brucei provides an excellent system for studies of many aspects of cell biology, including cell structure and morphology, organelle positioning, cell division and protein trafficking. However, the trypanosome has a complex life cycle in which
Matthews, Keith R
core +1 more source
Infections with extracellular trypanosomes require control by efficient innate immune mechanisms and can result in the destruction of the mammalian humoral immune system [PDF]
Salivarian trypanosomes are extracellular parasites that affect humans, livestock, and game animals around the world. Through co-evolution with the mammalian immune system, trypanosomes have developed defense mechanisms that allow them to thrive in blood,
Magez, Stefan+3 more
core +1 more source