Results 101 to 110 of about 18,366 (207)

Hydrazinated geraniol derivatives as potential broad‐spectrum antiprotozoal agents

Archiv der Pharmazie, Volume 357, Issue 10, October 2024.
Hydrazinated geraniol derivatives were synthesised and tested in vitro against different parasitic protozoans of clinical relevance, including Trypanosoma brucei brucei, Trypanosoma brucei rhodesiense, Trypanosoma cruzi and Leishmania infantum. Compounds 6, 8, 13, 14 and 15 demonstrated low micromolar activity against the different parasites.
Joelien Jooste, Lesetja J. Legoabe, Kayhan Ilbeigi, Guy Caljon, Richard M. Beteck   +4 more
wiley   +1 more source

Cholesterol transport and beyond: Illuminating the versatile functions of HDL apolipoproteins through structural insights and functional implications

BioFactors, Volume 50, Issue 5, Page 922-956, September/October 2024.
High‐density lipoproteins are versatile lipoprotein nanoparticles that have pleotropic functions in regulating lipid metabolism, innate immunity, and protection of cardiovascular system. They comprise of several proteins among which 15 apolipoproteins are the major proteins, with diverse functions.
Aishwarya Sudam Bhale, Olivier Meilhac, Christian Lefebvre d'Hellencourt, Mookambeswaran A. Vijayalakshmi, Krishnan Venkataraman   +4 more
wiley   +1 more source

Trypanosomes and gut microbiota interactions in triatomine bugs and tsetse flies: A vectorial perspective

Medical and Veterinary Entomology, Volume 38, Issue 3, Page 253-268, September 2024.
Trypanosoma sp. presence modulates or has zero effect on gut microbiota composition. Microbiota presence modulates or has zero effect on Trypanosoma sp. growth. Vector biology of triatomine bugs and tsetse flies influences their gut microbiota composition.
Zeph Nelson Omondi, Ayşe Caner, Suha Kenan Arserim   +2 more
wiley   +1 more source

Silent Human Trypanosoma brucei gambiense Infections around the Old Gboko Sleeping Sickness Focus in Nigeria

Journal of Parasitology Research, 2016
Trypanosoma brucei gambiense causes Gambian trypanosomosis, a disease ravaging affected rural parts of Sub-Saharan Africa. We screened 1200 human blood samples for T. b.
Karshima Solomon Ngutor, Lawal A. Idris, Okubanjo Oluseyi Oluyinka   +2 more
doaj   +1 more source

Comparative Genomics of Glossina palpalis gambiensis and G. morsitans morsitans to Reveal Gene Orthologs Involved in Infection by Trypanosoma brucei gambiense

Frontiers in Microbiology, 2017
Blood-feeding Glossina palpalis gambiense (Gpg) fly transmits the single-celled eukaryotic parasite Trypanosoma brucei gambiense (Tbg), the second Glossina fly African trypanosome pair being Glossina morsitans/T.brucei rhodesiense. Whatever the T. brucei
Illiassou Hamidou Soumana, Bernadette Tchicaya, S. Rialle, H. Parrinello, Anne Geiger   +4 more
semanticscholar   +1 more source

Epidemiology of human African trypanosomiasis

Clinical Epidemiology, 2014
Jose R Franco,1 Pere P Simarro,1 Abdoulaye Diarra,2 Jean G Jannin1 1World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland; 2World Health Organization, Inter Country Support ...
Franco JR, Simarro PP, Diarra A, Jannin JG   +3 more
doaj  

Human African Trypanosomiasis Transmission, Kinshasa, Democratic Republic of Congo

Emerging Infectious Diseases, 2006
To investigate the epidemiology of human African trypanosomiasis (sleeping sickness) in Kinshasa, Democratic Republic of Congo, 2 entomologic surveys were conducted in 2005.
Gustave Simo, Philemon Mansinsa Diabakana, Victor Kande Betu Ku Mesu, Emile Zola Manzambi, Gaelle Ollivier, Tazoacha Asonganyi, Gerard Cuny, Pascal Grébaut   +7 more
doaj   +1 more source

Variant Surface Glycoprotein gene repertoires in Trypanosoma brucei have diverged to become strain-specific

BMC Genomics, 2007
Background In a mammalian host, the cell surface of African trypanosomes is protected by a monolayer of a single variant surface glycoprotein (VSG). The VSG is central to antigenic variation; one VSG gene is expressed at any one time and there is a low ...
Sharma Reuben, Mott Helen, Jones Nicola G, Picozzi Kim, Hutchinson O Clyde, Welburn Susan C, Carrington Mark   +6 more
doaj   +1 more source

Referee report. For: Modelling host-Trypanosoma brucei gambiense interactions in vitro using human induced pluripotent stem cell-derived cortical brain organoids [version 1; peer review: 1 approved with reservations]

, 2023
David M. Smith
openalex   +1 more source

Heme-deficient metabolism and impaired cellular differentiation as an evolutionary trade-off for human infectivity in Trypanosoma brucei gambiense [PDF]

, 2020
Eva Horáková, Laurence Lecordier, Paula Cunha, Roman Sobotka, Piya Changmai, Catharina J. M. Langedijk, Jan Van Den Abbeele, Benoît Vanhollebeke, Julius Lukeš   +8 more
openalex   +1 more source