Characterization of Trypanosoma brucei gambiense variant surface glycoprotein LiTat 1.5 [PDF]
Genetics and molecular research : GMR, 2012 At present, all available diagnostic antibody detection tests for Trypanosoma brucei gambiense human African trypanosomiasis are based on predominant variant surface glycoproteins (VSGs), such as VSG LiTat 1.5. During investigations aiming at replacement
Büscher, P. +4 more
core +4 more sources
The TgsGP Gene Is Essential for Resistance to Human Serum in Trypanosoma brucei gambiense
PLoS Pathogens, 2013 Trypanosoma brucei gambiense causes 97% of all cases of African sleeping sickness, a fatal disease of sub-Saharan Africa. Most species of trypanosome, such as T. b.
Paul Capewell +2 more
exaly +2 more sources
PLoS Neglected Tropical Diseases, 2017 BackgroundImportant control efforts have led to a significant reduction of the prevalence of human African trypanosomiasis (HAT) in Côte d'Ivoire, but the disease is still present in several foci.
Hamidou Ilboudo +2 more
exaly +2 more sources
Case of Nigeria-Acquired Human African Trypanosomiasis in United Kingdom, 2016 [PDF]
Emerging Infectious Diseases, 2017 Human African trypanosomiasis has not been reported in Nigeria since 2012. Nevertheless, limitations of current surveillance programs mean that undetected infections may persist.
Akish Luintel +6 more
doaj +5 more sources
Neural Damage in Experimental Trypanosoma brucei gambiense Infection: Hypothalamic Peptidergic Sleep and Wake-Regulatory Neurons [PDF]
Frontiers in Neuroanatomy, 2018 Neuron populations of the lateral hypothalamus which synthesize the orexin (OX)/hypocretin or melanin-concentrating hormone (MCH) peptides play crucial, reciprocal roles in regulating wake stability and sleep.
Claudia Laperchia +5 more
doaj +2 more sources
Target product profile: diagnostic test for <i>Trypanosoma brucei gambiense</i>. [PDF]
Bull World Health Organ, 2023 Human African trypanosomiasis is a life-threatening parasitic infection endemic to sub-Saharan Africa. Around 95% of cases are due to Trypanosoma brucei gambiense, found in western and central Africa. Clinical signs and symptoms are nonspecific, current diagnostic tests are not sufficiently accurate, and parasitological confirmation of infection ...
Priotto G +14 more
europepmc +3 more sources
Trypanosoma brucei gambiense-iELISA: A Promising New Test for the Post-Elimination Monitoring of Human African Trypanosomiasis [PDF]
Clinical Infectious Diseases, 2021 Manon Geerts, Nick Van Reet, Kat S Rock
exaly +2 more sources
Target product profile: <i>Trypanosoma brucei gambiense</i> test to verify elimination. [PDF]
Bull World Health Organ, 2023 Human African trypanosomiasis is a life-threatening parasitic infection transmitted by the tsetse fly in sub-Saharan Africa. The most common form is caused by Trypanosoma brucei gambiense, with humans as the main reservoir. Diagnosis in the field requires microscopic examination performed by specifically trained personnel.
Priotto G +14 more
europepmc +3 more sources
Trypanosoma brucei gambiense in domestic livestock of Kogo and Mbini foci (Equatorial Guinea)
Tropical Medicine and International Health, 2009 OBJECTIVE: To evaluate Trypanosoma brucei gambiense infection in peri-domestic livestock from Kogo and Mbini foci (Equatorial Guinea) in order to investigate its possible implication in the sleeping sickness transmission cycle in these hypoendemic foci ...
Jorge Cano
exaly +2 more sources
Diagnostic accuracy of loopamp Trypanosoma brucei detection kit for diagnosis of human African trypanosomiasis in clinical samples. [PDF]
PLoS Neglected Tropical Diseases, 2013 BACKGROUND: Molecular methods have great potential for sensitive parasite detection in the diagnosis of human African trypanosomiasis (HAT), but the requirements in terms of laboratory infrastructure limit their use to reference centres.
Patrick Mitashi +9 more
doaj +5 more sources