Results 41 to 50 of about 4,641 (209)

Population genetics of trypanosoma brucei rhodesiense: clonality and diversity within and between foci [PDF]

, 2013
African trypanosomes are unusual among pathogenic protozoa in that they can undergo their complete morphological life cycle in the tsetse fly vector with mating as a non-obligatory part of this development.
C. Michael R. Turner, Cooper, Anneli, Duffy, Craig W, Duffy, C.W., C Michael R Turner, Annette MacLeod, Cooper Anneli, MacLeod Annette, Lorna MacLean (126077), Lindsay Sweeney, MacLeod, A., MacLeod, Annette, Craig W. Duffy, Morrison, Liam; id_orcid, Tait, Andy, Morrison, L.J., Craig W Duffy, Sternberg, Jeremy, Sweeney, Lindsay, Morrison Liam J., Cooper, A., Sternberg, J., Tait, A., Duffy, Craig W., Jeremy Sternberg, Andy Tait, Lindsay Sweeney (51760), MacLean Lorna, Tait Andy, Duffy, Craig, Liam J Morrison, Tait, Andrew, Liam J. Morrison, Andy Tait (12786), Turner, C.M.R., Sweeney Lindsay, Liam J. Morrison (211421), Duffy Craig W., C. Michael R. Turner (12785), Turner, C M, MacLean, L., Craig W. Duffy (429693), Anneli Cooper (51759), Anneli Cooper, Turner, C Michael R, Morrison, Liam J, Jeremy Sternberg (485210), Sweeney, L., Annette MacLeod (12779), Sternberg Jeremy, Lorna MacLean, Turner C. Michael R., MacLean, Lorna, Morrison, Liam J., Turner, C. Michael R.   +54 more
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An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei [PDF]

, 2015
Elucidating the mechanism of action of trypanocidal compounds is an important step in the development of more efficient drugs against Trypanosoma brucei. In a screening approach using an RNAi library in T. brucei bloodstream forms, we identified a member
Vial, Henri, Niemann, Moritz, de Macêdo, Juan P., Isabel Roditi, Henri Vial (24552), Moritz Niemann, Mäser, Pascal, Juan P. de Macêdo (735541), Bütikofer, Peter, Barrett, Michael P., Michael P Barrett, Gabriela Schumann Burkard (259590), Pascal Mäser (87895), Peter Bütikofer, Moritz Niemann (735542), Pascal Mäser, Horn, David, André Schneider (74039), Juan P de Macêdo, Isabel Roditi (60386), André Schneider, Roditi, Isabel, Schumann Burkard, Gabriela, Henri Vial, Schneider, André, Schumann-Burkard, Gabriela, Gabriela Schumann Burkard, Michael P. Barrett (167748), Peter Bütikofer (147146)   +28 more
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Untreated Human Infections by Trypanosoma brucei gambiense Are Not 100% Fatal

PLoS Neglected Tropical Diseases, 2012
El resultado final de la infección por Trypanosoma brucei gambiense, el principal agente de la enfermedad del sueño, siempre se ha considerado invariablemente fatal. Si bien los informes escasos y antiguos han mencionado casos de autocuración en pacientes no tratados, estos estudios sufrieron la falta de herramientas de diagnóstico precisas disponibles
Vincent Jamonneau, Hamidou Ilboudo, Jacques Kaboré, Dramane Kaba, Mathurin Koffi, Philippe Solano, André Garcia, David Courtin, Claude Laveissière, Lingué Kouakou, Philippe Büscher, Bruno Bucheton   +11 more
openaire   +5 more sources

The natural progression of gambiense sleeping sickness: what is the evidence? [PDF]

, 2008
Gambiense human African trypanosomiasis (HAT, sleeping sickness) is widely assumed to be 100% pathogenic and fatal. However, reports to the contrary exist, and human trypano-tolerance has been postulated.
Filipe, João AN, Francesco Checchi, Barrett, M.P., Daniel Chandramohan, Checchi Francesco, Barrett, Michael P, Checchi, Francesco, Filipe, J.A.N., Chandramohan, Daniel, João A N Filipe, Barrett Michael P., Michael P Barrett, Filipe João A. N., Checchi, F., Chandramohan, D., Chandramohan Daniel   +15 more
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Dynamic modelling under uncertainty: the case of Trypanosoma brucei energy metabolism [PDF]

, 2012
Kinetic models of metabolism require detailed knowledge of kinetic parameters. However, due to measurement errors or lack of data this knowledge is often uncertain.
Achcar, Fiona,, Kerkhoven Eduard J., Barrett, M.P., Breitling, Rainer, Breitling, R., Fiona Achcar, Breitling, Rainer,, Bakker, Barbara M.; id_orcid, Achcar, Fiona, Achcar, F., Eduard J. Kerkhoven (187101), Fiona Achcar (187100), Breitling Rainer, Bakker Barbara M., SilicoTryp Consortium, Barrett, Michael P., Rainer Breitling (4371), Michael P Barrett, Bakker, B.M., Barbara M. Bakker (102159), Barrett, Michael P.,, Bakker, Barbara M., Barbara M Bakker, Kerkhoven, Eduard J, Matthews, Keith; id_orcid, Kerkhoven, Eduard J.,, Bakker, Barbara M, Rainer Breitling, Barrett, Michael P, Kerkhoven, E.J., ?, ?, Eduard J Kerkhoven, Achcar Fiona, Barrett Michael P., Bakker, Barbara M.,, Kerkhoven, Eduard J., Michael P. Barrett (167748)   +36 more
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Les glossines de l'agglomération brazzavilloise. III. Rôle vecteur dans les trypanosomoses animales et humaine

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1987
Depuis l'élimination en 1985 des glossines du centre ville de la capitale congolaise, la trypanosomose animale à trypanosoma congolense y a totalement disparu. Cependant, en périphérie Sud de Brazzaville parallélement à l'épizootie à t.
F. Noireau, A. Toudic, J.P. Gouteux, N. Bissadidi, Jean-Louis Frézil, J.P. Duteurtre   +5 more
doaj   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Regulation of Trypanosoma brucei Total and Polysomal mRNA during Development within Its Mammalian Host [PDF]

, 2013
The gene expression of Trypanosoma brucei has been examined extensively in the blood of mammalian hosts and in forms found in the midgut of its arthropod vector, the tsetse fly.
Ivens, A, Pegine Walrad (267013), Capewell, P, Ivens, Alasdair, Terry K Smith, Keith R Matthews, Macgregor, Paula, Matthews, Keith R; id_orcid, Bringaud, F, Bringaud, Frederic, Smith, Terry K., Paul Capewell (137761), Katelyn Fenn (22199), Paula Macgregor, Smith, T, Fenn, K, Paul Capewell, Stephanie Monk, MacGregor, P, Alasdair Ivens (33327), Katelyn Fenn, Keith R. Matthews (199001), Matthews, K, Matthews, Keith R., Frederic Bringaud, Walrad, Pegine, Monk, S, Terry K. Smith (112550), Walrad, P, Stephanie Monk (427018), Matthews, Keith R, Keith R. Matthews, Frederic Bringaud (5655364), Smith, Terry K, Monk, Stephanie, Pegine Walrad, Fenn, Katelyn, Capewell, Paul, Alasdair Ivens, Terry K. Smith, Paula MacGregor (198985)   +40 more
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Synthesis, Electrochemistry, In Vitro Antiprotozoal Efficacy and Mechanistic Study of Novel ‘Ferrantoin’ and Related Derivatives

Applied Organometallic Chemistry, Volume 40, Issue 7, July 2026.
1,2‐Disubstituted ferrocene analogues bearing hydantoin or rhodanine synthons were synthesised and assessed for antitrypanosomatid activity. An antileishmanial early lead, analogue 23, acting through ROS generation and hence oxidative stress, was uncovered.
Maryna Saayman, Janine Aucamp, Helena D. Janse van Rensburg, Christina Kannigadu, Rotondwa Mphephu, Andrew J. Swarts, Keisuke Suganuma, David D. N'Da   +7 more
wiley   +1 more source

The flagella connector of Trypanosoma brucei : an unusual mobile transmembrane junction. [PDF]

, 2004
Throughout its elongation, the new flagellum of the procyclic form of the African trypanosome Trypanosoma brucei is tethered at its tip to the lateral aspect of the old flagellum.
Sue Vaughan, Vaughan, Sue, Vaughan, S, Davidge, J, Moreira-Leite, Flavia, Keith Gull, Baines, A, Flavia Moreira-Leite, McKean, PG, Gull, K, Moreira-Leite, F, Jacqueline Davidge, Baines, Andrea, Briggs, Laura, Gull, Keith, Laura J. Briggs, McKean, Paul G., Paul G. McKean, Davidge, Jacqueline, Briggs, LJ, Andrea Baines   +20 more
core   +1 more source