Results 51 to 60 of about 7,822 (201)

Effectiveness of a 10-day melarsoprol schedule for the treatment of late-stage human African trypanosomiasis: confirmation from a multinational study (IMPAMEL II). [PDF]

, 2005
BACKGROUND: Treatment of late-stage human African trypanosomiasis (HAT) with melarsoprol can be improved by shortening the regimen. A previous trial demonstrated the safety and efficacy of a 10-day treatment schedule.
Asumu, P, Bilenge, C M M, Burri, C, Chappuis, F, Doua, F, Josenando, T, Manthelot, C R, Nangouma, A, Richer, M, Schmid, C, Simarro, P   +10 more
core   +2 more sources

Management of trypanosomiasis and leishmaniasis [PDF]

, 2012
<p>Background: The current treatments for human African trypanosomiasis (HAT), Chagas disease and leishmaniasis (collectively referred to as the kinetoplastid diseases) are far from ideal but, for some, there has been significant recent progress ...
Alsford, Alvar, Alvar, Barrett, Barrett, Ben Salah, Berman, Bern, Brun, Brun, Burri, Chappuis, Coura, Croft, Croft, El-Sayed, Frearson, Hailu, Jacobs, Jacobs, Le Loup, Lessa, M. P. Barrett, Miranda-Verastegui, Paine, Pinazo, Priotto, Rassi, Reithinger, Rodgers, S. L. Croft, Stuart, Sundar, Sundar, Sundar, Sundar, Torreele, Vanhollebeke, Vincent, Voogd   +39 more
core   +2 more sources

Spatially and genetically distinct African trypanosome virulence variants defined by host interferon-g response [PDF]

, 2007
We describe 2 spatially distinct foci of human African trypansomiasis in eastern Uganda. The Tororo and Soroti foci of <i>Trypanosoma brucei rhodesiense</i> infection were genetically distinct as characterized by 6 microsatellite and 1 ...
Anneli Cooper, Annette MacLeod, Bakhiet M, Bancroft GJ, Cattand P, Hertz CJ, Hunter CA, Jeremy M. Sternberg, Liam Morrison, Lindsay Sweeney, Lorna MacLean, Martin Odiit, Morrison LJ, Page RDM, Peter G. E. Kennedy, Schleifer KW, Schleifer KW, Sternberg JM, Woo PT, World Health Organization   +19 more
core   +1 more source

The challenge of Trypanosoma brucei gambiense sleeping sickness diagnosis outside Africa [PDF]

The Lancet Infectious Diseases, 2003
Sleeping sickness is a lethal African disease caused by parasites of the Trypanosoma brucei subspecies, which is transmitted by tsetse flies. Occasionally, patients are reported outside Africa. Diagnosis of such imported cases can be problematic when the infection is due to Trypanosoma brucei gambiense, the chronic form of sleeping sickness found in ...
Lejon, V., Boelaert, M., Jannin, J., Moore, A., Büscher, P.   +4 more
openaire   +3 more sources

Les glossines de l'agglomération brazzavilloise. III. Rôle vecteur dans les trypanosomoses animales et humaine

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1987
Depuis l'élimination en 1985 des glossines du centre ville de la capitale congolaise, la trypanosomose animale à trypanosoma congolense y a totalement disparu. Cependant, en périphérie Sud de Brazzaville parallélement à l'épizootie à t.
F. Noireau, A. Toudic, J.P. Gouteux, N. Bissadidi, Jean-Louis Frézil, J.P. Duteurtre   +5 more
doaj   +1 more source

Delineating neuroinflammation, parasite CNS invasion, and blood-brain barrier dysfunction in an experimental murine model of human African trypanosomiasis [PDF]

, 2017
Although Trypanosoma brucei spp. was first detected by Aldo Castellani in CSF samples taken from sleeping sickness patients over a century ago there is still a great deal of debate surrounding the timing, route and effects of transmigration of the ...
Bradley, Barbara, Kennedy, Peter G.E., Rodgers, Jean   +2 more
core   +1 more source

Phytochemical Diversity, Nutritional Values, and Biological Properties of Halopithys incurva (Hudson) Batters, 1902

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Halopithys incurva is a red macroalga distributed across the Mediterranean Sea and North‐East Atlantic, with occasional reports from the Indian Ocean. It exhibits a rich chemical diversity, including isoflavones, bromophenols, MAAs, pigments, phycobiliproteins, primary metabolites, and neuroactive compounds.
Youssra Aalilou, Abdelhakim Bouyahya, Kaoutar Benrahou, Mustapha Hassoun, Hanaa Moussa, Issam Ameziane El Hassani, Waleed Al Abdulmonem, Learn‐Han Lee, Gokhan Zengin, My El Abbes Faouzi   +9 more
wiley   +1 more source

Enzyme polymorphism and the identity of Trypanosoma brucei gambiense

Parasitology, 1987
SUMMARYThirty-two isolates from man in known areas of Gambian trypanosomiasis, in the Sudan, Kenya, Zaire, Nigeria, Ivory Coast, Burkina Faso, Liberia and Senegal, were examined by isoenzyme electrophoresis of 11 enzymes. Comparisons were also made with our previously published results on 23 other stocks of similar origins, which had been examined in ...
D G, Godfrey, C M, Scott, W C, Gibson, D, Mehlitz, U, Zillmann   +4 more
openaire   +2 more sources

A panel of Trypanosoma brucei strains tagged with blue and red-shifted luciferases for bioluminescent imaging in murine infection models. [PDF]

PLoS Neglected Tropical Diseases, 2014
BACKGROUND:Genetic engineering with luciferase reporter genes allows monitoring Trypanosoma brucei (T.b.) infections in mice by in vivo bioluminescence imaging (BLI). Until recently, luminescent T.b.
Nick Van Reet, Hélène Van de Vyver, Patient Pati Pyana, Anne Marie Van der Linden, Philippe Büscher   +4 more
doaj   +1 more source

Stunning Intricacies of RNA Editing Complexes RECC, RESC, and REH2C: Functional Organization, Developmental Regulation, and Evolutionary History in Kinetoplastid Protists

WIREs RNA, Volume 17, Issue 2, March/April 2026.
U‐indel RNA editing targets mRNA:gRNA duplexes through three key complexes that collectively govern assembly, specificity, catalysis, and developmental regulation. Modern tools, including artificial intelligence, analyze the organization, dynamics, and evolution of the remarkable holo‐editosome, opening new avenues in RNA biology and therapy.
Suzanne M. McDermott, Julius Lukeš, Laurie K. Read, Reza Salavati, Achim Schnaufer, Sara L. Zimmer, Jason Carnes, Alasdair Ivens, Naghmeh Poorinmohammad, Nicholas J. Savill, Dave Speijer, Ken Stuart, Kristína Záhonová, Poorya Mirzavand Borujeni, Zihao Chen, Cody Goode, Sunil Kumar Sharma, Lars O’Hara, Jorge Cruz‐Reyes   +18 more
wiley   +1 more source