Results 31 to 40 of about 3,726 (164)
African Trypanosomiasis Research at a Crossroads: Bibliometric and Systematic Insights for the Future. [PDF]
Aim Despite a reduction in the overall incidence and prevalence in the last two decades, trypanosomiasis continues to be a public health concern in Africa. This study was designed to comprehensively evaluate current trends in trypanosomiasis research using bibliometric approaches to uncover emerging topics and knowledge gaps, thereby guiding future ...
Ogra IO +7 more
europepmc +2 more sources
We have evaluated whether sequence polymorphisms in the rRNA intergenic spacer region can be used to study the relatedness of two subspecies of Trypanosoma brucei. Thirteen T. brucei isolates made up of 6 T. b. brucei and 7 T. b. gambiense were analyzed using restriction fragment length polymorphism (RFLP).
Agbo, E.C. +3 more
openaire +3 more sources
Enzyme polymorphism and the identity of Trypanosoma brucei gambiense
SUMMARYThirty-two isolates from man in known areas of Gambian trypanosomiasis, in the Sudan, Kenya, Zaire, Nigeria, Ivory Coast, Burkina Faso, Liberia and Senegal, were examined by isoenzyme electrophoresis of 11 enzymes. Comparisons were also made with our previously published results on 23 other stocks of similar origins, which had been examined in ...
D G, Godfrey +4 more
openaire +2 more sources
Untreated Human Infections by Trypanosoma brucei gambiense Are Not 100% Fatal
El resultado final de la infección por Trypanosoma brucei gambiense, el principal agente de la enfermedad del sueño, siempre se ha considerado invariablemente fatal. Si bien los informes escasos y antiguos han mencionado casos de autocuración en pacientes no tratados, estos estudios sufrieron la falta de herramientas de diagnóstico precisas disponibles
Vincent Jamonneau +11 more
openaire +5 more sources
Depuis l'élimination en 1985 des glossines du centre ville de la capitale congolaise, la trypanosomose animale à trypanosoma congolense y a totalement disparu. Cependant, en périphérie Sud de Brazzaville parallélement à l'épizootie à t.
F. Noireau +5 more
doaj +1 more source
HIV‐associated nephropathy: A decade of clinical outcomes, global disparities and emerging promise
Abstract Objective To review the pathogenesis, epidemiology, clinical presentation, management and outcomes of HIV‐associated nephropathy (HIVAN), with emphasis on global disparities, genetic susceptibility (APOL1) and emerging therapeutic and technological advances.
Deepak V. Pathiyil +4 more
wiley +1 more source
Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva +10 more
wiley +1 more source
Trypanosomes are parasitic protozoa that cause severe diseases in humans and animals. The most important species of Trypanosmes include Trypanosoma evansi and Trypanosoma brucei gambiense.
Shoaib Ashraf +6 more
doaj +1 more source
Cathepsin-L can resist lysis by human serum in Trypanosoma brucei brucei.
Closely related African trypanosomes cause lethal diseases but display distinct host ranges. Specifically, Trypanosoma brucei brucei causes nagana in livestock but fails to infect humans, while Trypanosoma brucei gambiense and Trypanosoma brucei ...
Sam Alsford +4 more
doaj +1 more source
Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi +4 more
wiley +1 more source

