Results 31 to 40 of about 4,641 (209)

Whole-Genome Sequencing of Trypanosoma brucei Reveals Introgression between Subspecies That Is Associated with Virulence

mBio, 2013
Human African trypanosomiasis is caused by two subspecies of Trypanosoma brucei. Trypanosoma brucei rhodesiense is found in East Africa and frequently causes acute disease, while Trypanosoma brucei gambiense is found in West Africa and is associated with
Ian Goodhead, Paul Capewell, J. Wendi Bailey, Tanja Beament, Michael Chance, Suzanne Kay, Sarah Forrester, Annette MacLeod, Mark Taylor, Harry Noyes, Neil Hall   +10 more
doaj   +1 more source

Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from northwestern Uganda following melarsoprol withdrawal [PDF]

, 2009
Human African trypanosomiasis (HAT) manifests as a chronic infection caused by <i>Trypanosoma brucei gambiense</i>, or as a more acute form due to <i>T. b. rhodesiense</i>.
Barbara Nerima, Pascal Mäser, Nerima, B., Barrett, M.P., Nerima, Barbara, de Koning Harry P., Matovu, E., Kazibwe, Anne J., Anne J N Kazibwe, Kazibwe Anne J. N., Enock Matovu, Kazibwe, A.J.N., Mäser, Pascal, De Koning, H.P., Matovu Enock, Harry P de Koning, Barrett Michael P., de Koning, Harry P., Barrett, Michael P., Michael P Barrett, Mäser, P., Mäser Pascal, Matovu, Enock, Nerima Barbara   +23 more
core   +1 more source

Human and animal Trypanosomes in Côte d'Ivoire form a single breeding population.

PLoS ONE, 2013
BackgroundTrypanosoma brucei is the causative agent of African Sleeping Sickness in humans and contributes to the related veterinary disease, Nagana. T. brucei is segregated into three subspecies based on host specificity, geography and pathology. T.
Paul Capewell, Anneli Cooper, Craig W Duffy, Andy Tait, C Michael R Turner, Wendy Gibson, Dieter Mehlitz, Annette Macleod   +7 more
doaj   +1 more source

Screening of Trypanosoma brucei gambiense in domestic livestock and tsetse flies from an insular endemic focus (Luba, Equatorial Guinea). [PDF]

, 2010
BACKGROUND: Sleeping sickness is spread over 36 Sub-Saharan African countries. In West and Central Africa, the disease is caused by Trypanosoma brucei gambiense, which produces a chronic clinical manifestation.
Abaga, Simón, Pedro Ndongo-Asumu, Ochando, Jordi, Ndong-Mabale Nicolás, Carmen García-Estébanez, Nicolás Ndong-Mabale, Ndong-Mabale, Nicolás, Agustín Benito, Carlos Cordon-Obras, Ndongo-Asumu, Pedro, Benito Agustín, García-Estébanez, Carmen, Cano, Jorge, Cordon-Obras, Carlos, Cano Jorge, Benito, Agustín, Cordon-Obras Carlos, Simón Abaga, Abaga Simón, Ndongo-Asumu Pedro, Jorge Cano, García-Estébanez Carmen   +21 more
core   +1 more source

Free-ranging pigs identified as a multi-reservoir of Trypanosoma brucei and Trypanosoma congolense in the Vavoua area, a historical sleeping sickness focus of Côte d'Ivoire.

PLoS Neglected Tropical Diseases, 2021
BackgroundThe existence of an animal reservoir of Trypanosoma brucei gambiense (T. b. gambiense), the agent of human African trypanosomiasis (HAT), may compromise the interruption of transmission targeted by World Health Organization.
Barkissa Mélika Traoré, Mathurin Koffi, Martial Kassi N'Djetchi, Dramane Kaba, Jacques Kaboré, Hamidou Ilboudo, Bernadin Ahouty Ahouty, Minayégninrin Koné, Bamoro Coulibaly, Thomas Konan, Adeline Segard, Lingué Kouakou, Thierry De Meeûs, Sophie Ravel, Philippe Solano, Jean-Mathieu Bart, Vincent Jamonneau   +16 more
doaj   +1 more source

Isolation, propagation and characterization of "Trypanosoma brucei gambiense" from human African trypanosomosis patients in south Sudan [PDF]

, 2006
Sleeping sickness or Human African trypanosomosis (HAT) is a protozoal disease that is transmitted by tsetse fly vectors in Africa. Sleeping sickness due to T. b.
Maina, Naomi Wangari Njogu
core   +1 more source

Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign [PDF]

, 2012
Human African Trypanosomiasis (HAT) is caused by two trypanosome sub-species, Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Drugs available for the treatment of HAT have significant issues related to difficult administration regimes ...
Moawad, S. R., Baell, Jonathan, Sykes, Melissa L, Kaiser Marcel, Moawad Sarah R., Ganame Danny, Sykes Melissa L., Chatelain Eric, Avery Vicky M., Vicky M Avery, Ioset Jean-Robert, Ganame, D., Baell, Jonathan Bayldon, Avery, Vicky, Moawad, Sarah R., Kaiser, Marcel, Baell Jonathan B., Avery, V. M., Danny Ganame, Baell, Jonathan B, Marcel Kaiser, Melissa L Sykes, Ioset, J. R., Ioset, Jean, Chatelain, E., Kaiser, M., Moawad, Sarah R, Avery, Vicky M, Baell, J. B., Jonathan B Baell, Sykes, M. L., Sykes, Melissa, Ganame, Danny, Ioset, Jean-Robert, Sarah R Moawad, Chatelain, Eric, Moawad, Sarah, Jean-Robert Ioset, Baell, Jonathan B., Eric Chatelain, Ioset, Jean Robert   +40 more
core   +1 more source

Measure of Molecular Diversity within the Trypanosoma brucei Subspecies Trypanosoma brucei brucei and Trypanosoma brucei gambiense as Revealed by Genotypic Characterization

Experimental Parasitology, 2001
We have evaluated whether sequence polymorphisms in the rRNA intergenic spacer region can be used to study the relatedness of two subspecies of Trypanosoma brucei. Thirteen T. brucei isolates made up of 6 T. b. brucei and 7 T. b. gambiense were analyzed using restriction fragment length polymorphism (RFLP).
Agbo, E.C., Majiwa, P.A.O., Classsen, E.J.H.M., Roos, M.H.   +3 more
openaire   +3 more sources

Identification of sVSG117 as an immunodiagnostic antigen and evaluation of a dual-antigen lateral flow test for the diagnosis of human african trypanosomiasis [PDF]

, 2014
The diagnosis of human African trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense relies mainly on the Card Agglutination Test for Trypanosomiasis (CATT). There is no immunodiagnostic for HAT caused by T. b. rhodesiense.
Sastry Lalitha, Lalitha Sastry, Lauren Sullivan, Sullivan Lauren, Ferguson, Michael A J; id_orcid, Fleming Jennifer, Steven J Wall, Sullivan, Lauren, Fleming, Jennifer, Angela Mehlert, Michael A J Ferguson, Mehlert Angela, Sastry, Lalitha, Wall, Steven J., Jennifer Fleming, Ferguson Michael A. J., Ferguson, Michael A. J., Wall, Steven J, Wall Steven J., Fleming, Jennifer R., Mehlert, Angela   +20 more
core   +1 more source

Enzyme polymorphism and the identity of Trypanosoma brucei gambiense

Parasitology, 1987
SUMMARYThirty-two isolates from man in known areas of Gambian trypanosomiasis, in the Sudan, Kenya, Zaire, Nigeria, Ivory Coast, Burkina Faso, Liberia and Senegal, were examined by isoenzyme electrophoresis of 11 enzymes. Comparisons were also made with our previously published results on 23 other stocks of similar origins, which had been examined in ...
D G, Godfrey, C M, Scott, W C, Gibson, D, Mehlitz, U, Zillmann   +4 more
openaire   +2 more sources