Trypanosomatidae codon usage and GC distribution [PDF]
Memorias do Instituto Oswaldo Cruz, 1992 A study od Typanosomatidae GC distribution and codon usage is presented. The codon usage patterns in coincidence with the phylogenetical data are similar in Crithidia and Leishmania, whereas they are more divergent in Trypanosoma brucei and T. cruzi. The
Guilhermina Alonso +2 more
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Roles of ADP-Ribosylation during Infection Establishment by Trypanosomatidae Parasites [PDF]
Pathogens, 2023 ADP-ribosylation is a reversible post-translational protein modification, which is evolutionarily conserved in prokaryotic and eukaryotic organisms.
Joshua Dowling, Craig L. Doig
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Triatomíneos rupestres infectados por Trypanosomatidae, coletados em Quaraí, Rio Grande do Sul, 2003 Rupestrian triatomines infected by Trypanosomatidae, collected in Quaraí, Rio Grande do Sul, 2003 [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2006 Foram capturados triatomíneos rupestres em seis localidades do município de Quaraí-RS, com o intuito de verificar o índice de infecção por Trypanosomatidae, bem como o animal reservatório.
Luciamáre Perinetti Alves Martins +6 more
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TLR9 activation is triggered by the excess of stimulatory versus inhibitory motifs present in Trypanosomatidae DNA. [PDF]
PLoS Neglected Tropical Diseases, 2014 DNA sequences purified from distinct organisms, e.g. non vertebrate versus vertebrate ones, were shown to differ in their TLR9 signalling properties especially when either mouse bone marrow-derived- or human dendritic cells (DCs) are probed as target ...
Mélissa Erin Khan +9 more
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Preclinical Studies in Anti-Trypanosomatidae Drug Development [PDF]
Pharmaceuticals, 2021 The trypanosomatid parasites Trypanosoma brucei, Trypanosoma cruzi and Leishmania are the causative agents of human African trypanosomiasis, Chagas Disease and Leishmaniasis, respectively. These infections primarily affect poor, rural communities in the developing world, and are responsible for trapping sufferers and their families in a disease/poverty
Cintya Perdomo +8 more
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Inhibitors of Farnesyl Diphosphate Synthase and Squalene Synthase: Potential Source for Anti-Trypanosomatidae Drug Discovery [PDF]
Drugs and Drug Candidates, 2023 Trypanosomatids are mainly responsible for leishmaniasis, sleeping sickness, and Chagas disease, which are the most challenging among the neglected tropical diseases due to the problem of drug resistance.
Boniface Pone Kamdem +1 more
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Trypanosomatidae de importancia en salud pública en animales silvestres y sinantrópicos en un area rural del municipio Tovar del estado Mérida, Venezuela. [PDF]
Biomédica: revista del Instituto Nacional de Salud, 2006 Introducción. La enfermedad de Chagas y la leishmaniasis son patologías de gran importancia en salud pública debido a su alta frecuencia y amplia distribución en América Latina.
Héctor de Lima +4 more
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Comportamiento de flagelados de la familia Trypanosomatidae en dos medios de cultivo modificados [PDF]
Biomédica: revista del Instituto Nacional de Salud, 1988 Se reporta un medio de cultivo monofásico sólido (NNN modificado) y un medio monofásico líquido (RE I modificado) de gran utilidad para cultivos in vitro de flagelados de la Familia Trypanosomatidae.
Sofía Duque Beltrán +2 more
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Leptoconops nosopheris sp. n. (Diptera: Ceratopogonidae) and Paleotrypanosoma burmanicus gen. n., sp. n. (Kinetoplastida: Trypanosomatidae), a biting midge - trypanosome vector association from the Early Cretaceous [PDF]
Memorias do Instituto Oswaldo Cruz, 2008 Leptoconops nosopheris sp. n. (Diptera: Ceratopogonidae) is described from a blood-filled female biting midge in Early Cretaceous Burmese amber. The new species is characterized by a very elongate terminal flagellomere, elongate cerci, and an indistinct ...
George Poinar Jr.
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Amphibian Strategies Against Attacks by Flies: Host-Specificity and Threats. [PDF]
Ecol EvolSpecies interactions between Diptera flies and amphibians play a significant role in tropical ecosystems, but their ecology and evolution remain understudied. This review explores the costs flies impose on amphibians, such as pathogen transmission and disruption of communication systems, and highlights the evolutionary strategies employed by both ...
de Campos LLF +3 more
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