Results 11 to 20 of about 5,037 (202)

Roles of ADP-Ribosylation during Infection Establishment by Trypanosomatidae Parasites

Pathogens, 2023
ADP-ribosylation is a reversible post-translational protein modification, which is evolutionarily conserved in prokaryotic and eukaryotic organisms.
Joshua Dowling, Craig L. Doig
doaj   +2 more sources

Triatomíneos rupestres infectados por Trypanosomatidae, coletados em Quaraí, Rio Grande do Sul, 2003 Rupestrian triatomines infected by Trypanosomatidae, collected in Quaraí, Rio Grande do Sul, 2003 [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2006
Foram capturados triatomíneos rupestres em seis localidades do município de Quaraí-RS, com o intuito de verificar o índice de infecção por Trypanosomatidae, bem como o animal reservatório.
Luciamáre Perinetti Alves Martins, Roberto Esteves Pires Castanho, Cláudio Casanova, David Tibiriçá Caravelas, Guilherme Tardim Frias, Antônio Leite Ruas-Neto, João Aristeu da Rosa   +6 more
doaj   +2 more sources

TLR9 activation is triggered by the excess of stimulatory versus inhibitory motifs present in Trypanosomatidae DNA. [PDF]

PLoS Neglected Tropical Diseases, 2014
DNA sequences purified from distinct organisms, e.g. non vertebrate versus vertebrate ones, were shown to differ in their TLR9 signalling properties especially when either mouse bone marrow-derived- or human dendritic cells (DCs) are probed as target ...
Mélissa Erin Khan, Chloé Borde, Eduardo P C Rocha, Véronique Mériaux, Vincent Maréchal, Pedro Escoll, Sophie Goyard, Jean-Marc Cavaillon, Bénédicte Manoury, Noëlle Doyen   +9 more
doaj   +2 more sources

Inhibitors of Farnesyl Diphosphate Synthase and Squalene Synthase: Potential Source for Anti-Trypanosomatidae Drug Discovery

Drugs and Drug Candidates, 2023
Trypanosomatids are mainly responsible for leishmaniasis, sleeping sickness, and Chagas disease, which are the most challenging among the neglected tropical diseases due to the problem of drug resistance.
Boniface Pone Kamdem, Fabrice Fekam Boyom   +1 more
doaj   +2 more sources

Chromosome-level genome assembly of trypanosomatid parasite Lotmaria passim links chromosome duplication and divergence with infection of honey bees [PDF]

BMC Genomics
Background The protist family Trypanosomatidae includes parasites of insects, vertebrates, plants, and even other unicellular eukaryotes. The genomes of these species harbor clues to the evolution of parasitism, adaptation to new hosts, and infection of ...
Anthony Nearman, Anzhelika Butenko, Jay D Evans, Evan C Palmer-Young   +3 more
doaj   +2 more sources

Trypanosomatidae de importancia en salud pública en animales silvestres y sinantrópicos en un area rural del municipio Tovar del estado Mérida, Venezuela. [PDF]

Biomédica: revista del Instituto Nacional de Salud, 2006
Introducción. La enfermedad de Chagas y la leishmaniasis son patologías de gran importancia en salud pública debido a su alta frecuencia y amplia distribución en América Latina.
Héctor de Lima, José Carrero, Armando Rodríguez, Zoraya de Guglielmo, Noris Rodríguez   +4 more
doaj   +2 more sources

Comportamiento de flagelados de la familia Trypanosomatidae en dos medios de cultivo modificados [PDF]

Biomédica: revista del Instituto Nacional de Salud, 1988
Se reporta un medio de cultivo monofásico sólido (NNN modificado) y un medio monofásico líquido (RE I modificado) de gran utilidad para cultivos in vitro de flagelados de la Familia Trypanosomatidae.
Sofía Duque Beltrán, Elvia Cáceres Vega, Augusto Corredor Arjona   +2 more
doaj   +2 more sources

Amphibian Strategies Against Attacks by Flies: Host-Specificity and Threats. [PDF]

Ecol Evol
Species interactions between Diptera flies and amphibians play a significant role in tropical ecosystems, but their ecology and evolution remain understudied. This review explores the costs flies impose on amphibians, such as pathogen transmission and disruption of communication systems, and highlights the evolutionary strategies employed by both ...
de Campos LLF, Pinho LC, Neckel-Oliveira S, Bernal XE.   +3 more
europepmc   +2 more sources

Assessment of the Performance of Indirect Immunofluorescence Assay for Chagas Disease in Dogs Using a Reference Panel of Four Chimeric Proteins. [PDF]

Vet Med Sci
We evaluated the performance of an indirect immunofluorescence (IIF) assay for detecting anti‐Trypanosoma cruzi IgG in dogs using four chimeric IBMP antigens and latent class analysis. The IIF assay showed suboptimal sensitivity and overall accuracy compared to ELISA and LCA‐based methods.
Silva ÂAO, Costa TF, Fontes ND, Santos EF, Rocha AVVO, Miranda LM, Almeida-Souza F, Costa FB, Nogueira RMS, Sampaio DD, Celedon PAF, Zanchin NIT, Costa APD, Santos FLN.   +13 more
europepmc   +2 more sources

Leptoconops nosopheris sp. n. (Diptera: Ceratopogonidae) and Paleotrypanosoma burmanicus gen. n., sp. n. (Kinetoplastida: Trypanosomatidae), a biting midge - trypanosome vector association from the Early Cretaceous

Memorias do Instituto Oswaldo Cruz, 2008
Leptoconops nosopheris sp. n. (Diptera: Ceratopogonidae) is described from a blood-filled female biting midge in Early Cretaceous Burmese amber. The new species is characterized by a very elongate terminal flagellomere, elongate cerci, and an indistinct ...
George Poinar Jr.
doaj   +2 more sources