Results 41 to 50 of about 32,433 (251)

Imaging African trypanosomes [PDF]

open access: yesParasite Immunology, 2013
SummaryTrypanosoma brucei are extracellular kinetoplastid parasites transmitted by the blood‐sucking tsetse fly. They are responsible for the fatal disease human African trypanosomiasis (HAT), also known as sleeping sickness. In late‐stage infection, trypanosomes cross the blood–brain barrier (BBB) and invade the central nervous system (CNS) invariably
MacLean, L.   +3 more
openaire   +3 more sources

Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor

open access: yeseLife, 2014
The haptoglobin-haemoglobin receptor (HpHbR) of African trypanosomes allows acquisition of haem and provides an uptake route for trypanolytic factor-1, a mediator of innate immunity against trypanosome infection. In this study, we report the structure of
Harriet Lane-Serff   +4 more
doaj   +1 more source

Vector-Borne Blood Parasites of the Great-Tailed Grackle (Quiscalus mexicanus) in East-Central Texas, USA

open access: yesMicroorganisms, 2021
Great-tailed grackles (Quiscalus mexicanus) have dramatically expanded into North America over the past century. However, little is known about the blood that parasites they support.
Andrew J. Golnar   +5 more
doaj   +1 more source

Antigenic variation in the African trypanosome: molecular mechanisms and phenotypic complexity [PDF]

open access: yes, 2009
Antigenic variation is an immune evasion strategy that has evolved in viral, bacterial and protistan pathogens. In the African trypanosome this involves stochastic switches in the composition of a variant surface glycoprotein (VSG) coat, using a massive ...
Marcello, Lucio   +2 more
core   +1 more source

Glossina spp. gut bacterial flora and their putative role in fly-hosted trypanosome development

open access: yesFrontiers in Cellular and Infection Microbiology, 2013
Human African trypanosomiasis is caused by trypanosomes transmitted to humans by the tsetse fly, in which they accomplish their development into their infective metacyclic form. The crucial step in parasite survival occurs when it invades the fly midgut.
Anne eGeiger   +3 more
doaj   +1 more source

Flagellar membrane association via interaction with lipid rafts [PDF]

open access: yes, 2009
The eukaryotic flagellar membrane has a distinct composition from other domains of the plasmalemma. Our work shows that the specialized composition of the trypanosome flagellar membrane reflects increased concentrations of sterols and saturated fatty ...
Cieslak, John A.   +6 more
core   +2 more sources

Through the dark continent: African trypanosome development in the tsetse fly [PDF]

open access: yes, 2013
African trypanosomes are unicellular flagellated parasites causing trypanosomiases in Africa, a group of severe diseases also known as sleeping sickness in human and nagana in cattle.
Rotureau, Brice, Van Den Abbeele, Jan
core   +4 more sources

Global stability analysis of the disease-free equilibrium state of a mathematical model of trypanosomiasis

open access: yesJournal of Applied Sciences and Environmental Management, 2019
The global stability analysis represents a compound failure, mechanism which provides lower calculated factors of safety. In this research, the global stability analysis was used to propose a mathematically model of the transmission dynamics and control
K.M. Bello   +4 more
doaj   +1 more source

Comparative clinico-haematological analysis in young Zebu cattle experimentally infected with Trypanosoma vivax isolates from tsetse infested and non-tsetse infested areas of Northwest Ethiopia [PDF]

open access: yes, 2015
Background: Ethiopia, particularly in the Northwest region, is affected by both tsetse and non-tsetse fly transmitted trypanosomosis, with significant impact on livestock productivity. The aim of this study was to determine and compare clinical findings
Abebe, Getachew   +5 more
core   +2 more sources

ASSOCIATION OF TRYPANOSOME INFECTION WITH SPERM ANTIBODIES PRODUCTION IN RED SOKOTO (MARADI) GOATS [PDF]

open access: yesPakistan Veterinary Journal, 2006
A total of 1021 randomly selected serum samples of adult male goats that had been screened for trypanosome infection were assayed for sperm antibodies using the immunoperoxidase staining technique.
O. FAYEMI
doaj  

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