Results 31 to 40 of about 10,096 (175)
TbKINX1B: a novel BILBO1 partner and an essential protein in bloodstream form Trypanosoma brucei
The flagellar pocket (FP) of the pathogen Trypanosoma brucei is an important single copy structure that is formed by the invagination of the pellicular membrane.
Perdomo Doranda +10 more
doaj +1 more source
The developmental cell biology of Trypanosoma brucei [PDF]
Trypanosoma brucei provides an excellent system for studies of many aspects of cell biology, including cell structure and morphology, organelle positioning, cell division and protein trafficking. However, the trypanosome has a complex life cycle in which
Matthews, Keith R; id_orcid +1 more
core +1 more source
Spatially and genetically distinct African trypanosome virulence variants defined by host interferon-g response [PDF]
We describe 2 spatially distinct foci of human African trypansomiasis in eastern Uganda. The Tororo and Soroti foci of <i>Trypanosoma brucei rhodesiense</i> infection were genetically distinct as characterized by 6 microsatellite and 1 ...
Kennedy, PGE +31 more
core +1 more source
Flagellar membranes are rich in raft-forming phospholipids
The observation that the membranes of flagella are enriched in sterols and sphingolipids has led to the hypothesis that flagella might be enriched in raft-forming lipids.
Mauro Serricchio +9 more
doaj +1 more source
Apis mellifera filamentous virus (AmFV) is a large double stranded DNA virus of honey bees, but its relationship with other parasites and prevalence are poorly known.
Ulrike Hartmann +4 more
doaj +1 more source
Stumpy forms are the predominant transmissible forms of Trypanosoma brucei
Schuster et al. demonstrated that bloodstream slender forms of African trypanosomes are readily transmissible to young tsetse flies where they can complete their complex life cycle (Schuster et al., 2021).
Jean Marc Tsagmo Ngoune +4 more
doaj +1 more source
The haptoglobin-haemoglobin receptor (HpHbR) of African trypanosomes allows acquisition of haem and provides an uptake route for trypanolytic factor-1, a mediator of innate immunity against trypanosome infection. In this study, we report the structure of
Harriet Lane-Serff +4 more
doaj +1 more source
Objective Trypanosomosis is a disease of domestic animals and humans resulting from infection with parasitaemic protozoa of the genus Trypanosoma transmitted primarily by tsetse flies.
Behablom Meharenet, Dereje Alemu
doaj +1 more source
A CRISPR-based diagnostic tool to survey drug resistance in human African trypanosomiasis
The World Health Organization aims to eliminate human African trypanosomiasis caused by Trypanosoma brucei gambiense (gHAT) by 2030. With the decline of reported cases, maintaining active surveillance is essential, including for the potential emergence ...
Elena Pérez Antón +3 more
doaj +1 more source
AbstractCytokinesis is a crucial step in the cell division cycle whereby the cell membrane and underlying cortex is remodelled and drawn together to create two new daughter cells. While in many eukaryotic systems this process is accomplished by an actomyosin contractile ring, the protozoan parasite Trypanosoma brucei displays an unusual mechanism for ...
Farr, H, Gull, K
openaire +3 more sources

