Results 31 to 40 of about 15,773 (232)
Trypanosome motion represents an adaptation to the crowded environment of the vertebrate bloodstream [PDF]
Blood is a remarkable habitat: it is highly viscous, contains a dense packaging of cells and perpetually flows at velocities varying over three orders of magnitude. Only few pathogens endure the harsh physical conditions within the vertebrate bloodstream
Timothy Krüger +46 more
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The developmental cell biology of Trypanosoma brucei [PDF]
Trypanosoma brucei provides an excellent system for studies of many aspects of cell biology, including cell structure and morphology, organelle positioning, cell division and protein trafficking. However, the trypanosome has a complex life cycle in which
Matthews, Keith R; id_orcid +1 more
core +1 more source
Spatially and genetically distinct African trypanosome virulence variants defined by host interferon-g response [PDF]
We describe 2 spatially distinct foci of human African trypansomiasis in eastern Uganda. The Tororo and Soroti foci of <i>Trypanosoma brucei rhodesiense</i> infection were genetically distinct as characterized by 6 microsatellite and 1 ...
Kennedy, PGE +31 more
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Using molecular data for epidemiological inference: assessing the prevalence of Trypanosoma brucei rhodesiense in Tsetse in Serengeti, Tanzania [PDF]
Background: Measuring the prevalence of transmissible Trypanosoma brucei rhodesiense in tsetse populations is essential for understanding transmission dynamics, assessing human disease risk and monitoring spatio-temporal trends and the impact of control ...
Auty, Harriet K. +26 more
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Flagellar membranes are rich in raft-forming phospholipids
The observation that the membranes of flagella are enriched in sterols and sphingolipids has led to the hypothesis that flagella might be enriched in raft-forming lipids.
Mauro Serricchio +9 more
doaj +1 more source
Distinct, developmental stage-specific activation mechanisms of trypanosome VSG genes [PDF]
The metacyclic form of African trypanosomes is the first to express genes for the Variant Surface Glycoprotein (VSG) and it uses an unusually predictable subset of the VSG gene repertoire.
Matthews, K R; id_orcid +3 more
core +1 more source
Apis mellifera filamentous virus (AmFV) is a large double stranded DNA virus of honey bees, but its relationship with other parasites and prevalence are poorly known.
Ulrike Hartmann +4 more
doaj +1 more source
The haptoglobin-haemoglobin receptor (HpHbR) of African trypanosomes allows acquisition of haem and provides an uptake route for trypanolytic factor-1, a mediator of innate immunity against trypanosome infection. In this study, we report the structure of
Harriet Lane-Serff +4 more
doaj +1 more source
Objective Trypanosomosis is a disease of domestic animals and humans resulting from infection with parasitaemic protozoa of the genus Trypanosoma transmitted primarily by tsetse flies.
Behablom Meharenet, Dereje Alemu
doaj +1 more source
Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species [PDF]
Antigenic variation enables pathogens to avoid the host immune response by continual switching of surface proteins. The protozoan blood parasite Trypanosoma brucei causes human African trypanosomiasis ("sleeping sickness") across sub-Saharan Africa and ...
Browne, H. +58 more
core +1 more source

