Results 31 to 40 of about 15,773 (232)

Trypanosome motion represents an adaptation to the crowded environment of the vertebrate bloodstream [PDF]

open access: yes, 2012
Blood is a remarkable habitat: it is highly viscous, contains a dense packaging of cells and perpetually flows at velocities varying over three orders of magnitude. Only few pathogens endure the harsh physical conditions within the vertebrate bloodstream
Timothy Krüger   +46 more
core   +1 more source

The developmental cell biology of Trypanosoma brucei [PDF]

open access: yes, 2005
Trypanosoma brucei provides an excellent system for studies of many aspects of cell biology, including cell structure and morphology, organelle positioning, cell division and protein trafficking. However, the trypanosome has a complex life cycle in which
Matthews, Keith R; id_orcid   +1 more
core   +1 more source

Spatially and genetically distinct African trypanosome virulence variants defined by host interferon-g response [PDF]

open access: yes, 2007
We describe 2 spatially distinct foci of human African trypansomiasis in eastern Uganda. The Tororo and Soroti foci of <i>Trypanosoma brucei rhodesiense</i> infection were genetically distinct as characterized by 6 microsatellite and 1 ...
Kennedy, PGE   +31 more
core   +1 more source

Using molecular data for epidemiological inference: assessing the prevalence of Trypanosoma brucei rhodesiense in Tsetse in Serengeti, Tanzania [PDF]

open access: yes, 2012
Background: Measuring the prevalence of transmissible Trypanosoma brucei rhodesiense in tsetse populations is essential for understanding transmission dynamics, assessing human disease risk and monitoring spatio-temporal trends and the impact of control ...
Auty, Harriet K.   +26 more
core   +1 more source

Flagellar membranes are rich in raft-forming phospholipids

open access: yesBiology Open, 2015
The observation that the membranes of flagella are enriched in sterols and sphingolipids has led to the hypothesis that flagella might be enriched in raft-forming lipids.
Mauro Serricchio   +9 more
doaj   +1 more source

Distinct, developmental stage-specific activation mechanisms of trypanosome VSG genes [PDF]

open access: yes, 1990
The metacyclic form of African trypanosomes is the first to express genes for the Variant Surface Glycoprotein (VSG) and it uses an unusually predictable subset of the VSG gene repertoire.
Matthews, K R; id_orcid   +3 more
core   +1 more source

Dynamics of Apis mellifera Filamentous Virus (AmFV) Infections in Honey Bees and Relationships with Other Parasites

open access: yesViruses, 2015
Apis mellifera filamentous virus (AmFV) is a large double stranded DNA virus of honey bees, but its relationship with other parasites and prevalence are poorly known.
Ulrike Hartmann   +4 more
doaj   +1 more source

Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor

open access: yeseLife, 2014
The haptoglobin-haemoglobin receptor (HpHbR) of African trypanosomes allows acquisition of haem and provides an uptake route for trypanolytic factor-1, a mediator of innate immunity against trypanosome infection. In this study, we report the structure of
Harriet Lane-Serff   +4 more
doaj   +1 more source

Trypanosome infection rate in Glossina tachinoides: infested rivers of Limmu Kosa District Jimma Zone, Western Ethiopia

open access: yesBMC Research Notes, 2020
Objective Trypanosomosis is a disease of domestic animals and humans resulting from infection with parasitaemic protozoa of the genus Trypanosoma transmitted primarily by tsetse flies.
Behablom Meharenet, Dereje Alemu
doaj   +1 more source

Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species [PDF]

open access: yes, 2012
Antigenic variation enables pathogens to avoid the host immune response by continual switching of surface proteins. The protozoan blood parasite Trypanosoma brucei causes human African trypanosomiasis ("sleeping sickness") across sub-Saharan Africa and ...
Browne, H.   +58 more
core   +1 more source

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