Results 11 to 20 of about 25,661 (227)

Barcoding in trypanosomes [PDF]

Parasitology, 2017
SUMMARYTrypanosomes (genus Trypanosoma) are parasites of humans, and wild and domestic mammals, in which they cause several economically and socially important diseases, including sleeping sickness in Africa and Chagas disease in the Americas. Despite the development of numerous molecular diagnostics and increasing awareness of the importance of these ...
RACHEL HUTCHINSON, JAMIE R. STEVENS
openaire   +4 more sources

African trypanosomes [PDF]

Parasites & Vectors, 2019
African trypanosomes cause human African trypanosomiasis and animal African trypanosomiasis. They are transmitted by tsetse flies in sub-Saharan Africa. Although most famous for their mechanisms of immune evasion by antigenic variation, there have been recent important studies that illuminate important aspects of the biology of these parasites both in ...
Cayla, Mathieu, Rojas, Federico, Silvester, Eleanor, Venter, Frank, Matthews, Keith R.   +4 more
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Methods matter: the influence of method on infection estimates of the bumblebee parasite Crithidia bombi

Parasitology, 2023
The bumblebee gut parasite, Crithidia bombi, is widespread and prevalent in the field. Its interaction with Bombus spp. is a well-established epidemiological model.
Hannah S. Wolmuth-Gordon, Anisah Sharmin, Mark J. F. Brown   +2 more
doaj   +1 more source

Distinct mRNA and protein interactomes highlight functional differentiation of major eIF4F-like complexes from Trypanosoma brucei

Frontiers in Molecular Biosciences, 2022
Gene expression in pathogenic protozoans of the family Trypanosomatidae has several novel features, including multiple eIF4F-like complexes involved in protein synthesis.
Maria J. R. Bezerra, Maria J. R. Bezerra, Danielle M. N. Moura, Eden R. Freire, Fabiola B. Holetz, Christian R. S. Reis, Tallyta T. S. Monteiro, Adriana R. S. Pinto, Ning Zhang, Antonio M. Rezende, Antonio Pereira-Neves, Regina C. B. Q. Figueiredo, Christine Clayton, Mark C. Field, Mark C. Field, Mark Carrington, Osvaldo P. de Melo Neto   +16 more
doaj   +1 more source

Turnover of Variant Surface Glycoprotein in Trypanosoma brucei Is Not Altered in Response to Specific Silencing

mSphere, 2022
African trypanosomes evade the immune system of the mammalian host by the antigenic variation of the predominant glycosylphosphatidylinositol (GPI)-anchored surface protein, variant surface glycoprotein (VSG).
Mohamed Sharif, Paige Garrison, Peter Bush, James D. Bangs   +3 more
doaj   +1 more source

The trypanosome flagellum [PDF]

Journal of Cell Science, 2003
African Trypanosomes are flagellated protozoan parasites that cause sleeping sickness in humans and Nagana in cattle. During its life cycle, Trypanosoma brucei alternates between an insect vector (tsetse fly) and a mammalian host.
Vaughan, S, Gull, K
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Modulation of Virulence Factors during Trypanosoma cruzi Differentiation

Pathogens, 2022
Chagas disease is a neglected tropical disease caused by Trypanosoma cruzi. This protozoan developed several mechanisms to infect, propagate, and survive in different hosts.
Camila Oliveira, Fabíola Barbieri Holetz, Lysangela Ronalte Alves, Andréa Rodrigues Ávila   +3 more
doaj   +1 more source

Boarder control on the IFT train

eLife, 2014
New details are revealed about the system that transports proteins to the tip of flagella during growth.
Cécile Fort, Philippe Bastin
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Molecular identification of different trypanosome species and subspecies in tsetse flies of northern Nigeria [PDF]

, 2016
Background: Animal African Trypanosomiasis (AAT) is caused by several species of trypanosomes including Trypanosoma congolense, T. vivax, T. godfreyi, T. simiae and T. brucei. Two of the subspecies of T. brucei also cause Human African Trypanosomiasis.
Ciosi, Marc, Dede, Peter, Hamilton, Alana, Igbinosa, Igho Benjamin, Isaac, Clement, Masiga, Dan, Nmorsi, Oyebiguwa Patrick Goddey, Scullion, Kathleen Maria, Turner, C. Michael R.   +8 more
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The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing [PDF]

, 2018
Kinetoplastid parasites—trypanosomes and leishmanias—infect millions of humans and cause economically devastating diseases of livestock, and the few existing drugs have serious deficiencies.
Barrett, Michael P., Begolo, Daniela, Bengaly, Zakaria, Clayton, Christine, Freund, Yvonne, Gillingwater, Kirsten, Giordani, Federica, Pöhner, Ina, Rowan, Timothy G., Vincent, Isabel M., Wade, Rebecca C., Witty, Michael J.   +11 more
core   +3 more sources