Results 11 to 20 of about 10,096 (175)
Parasitology, 2010 SUMMARYAfrican trypanosomes have emerged as promising unicellular model organisms for the next generation of systems biology. They offer unique advantages, due to their relative simplicity, the availability of all standard genomics techniques and a long history of quantitative research.
Bakker, B. +8 more
openaire +4 more sources
Barcoding in trypanosomes [PDF]
Parasitology, 2017 SUMMARY Trypanosomes (genus Trypanosoma ) are parasites of humans, and wild and domestic mammals, in which they cause several economically and socially important diseases, including sleeping sickness in Africa and Chagas disease in the Americas.
RACHEL HUTCHINSON, JAMIE R. STEVENS
openaire +4 more sources
The evolution of immune genes in tsetse flies (Glossina) and insights into tsetse-symbiont-trypanosome interactions [PDF]
, 2022 Tsetse flies (genera Glossina) are the sole biological vectors of African Trypanosoma species, the infectious agents of African Trypanosomiasis.
Bruce, Robert
core +1 more source
Parasites & Vectors, 2019 African trypanosomes cause human African trypanosomiasis and animal African trypanosomiasis. They are transmitted by tsetse flies in sub-Saharan Africa. Although most famous for their mechanisms of immune evasion by antigenic variation, there have been recent important studies that illuminate important aspects of the biology of these parasites both in ...
Cayla, Mathieu +4 more
openaire +4 more sources
The trypanosome flagellum [PDF]
Journal of Cell Science, 2003 African Trypanosomes are flagellated protozoan parasites that cause sleeping sickness in humans and Nagana in cattle. During its life cycle, Trypanosoma brucei alternates between an insect vector (tsetse fly) and a mammalian host.
Vaughan, S, Gull, K
openaire +2 more sources
Journal of Hygiene, 1906 In a previous paper on Bird Trypanosomes it was pointed out that these organisms grew readily in the test-tube on blood agar and that the resulting forms resembled the flagellates which Schaudinn found in the gut of mosquitoes which had fed on owls infected with Halteridium and with H. Ziemanni.
Novy, F. G. +2 more
openaire +2 more sources
The Flagellum of Trypanosomes [PDF]
, 2005 Eukaryotic cilia and flagella are cytoskeletal organelles that are remarkably conserved from protists to mammals. Their basic unit is the axoneme, a well-defined cylindrical structure composed of microtubules and up to 250 associated proteins. These complex organelles are assembled by a dynamic process called intraflagellar transport.
Kohl, Linda, Bastin, Philippe
openaire +3 more sources
The flagella connector of Trypanosoma brucei : an unusual mobile transmembrane junction. [PDF]
, 2004 Throughout its elongation, the new flagellum of the procyclic form of the African trypanosome Trypanosoma brucei is tethered at its tip to the lateral aspect of the old flagellum.
Vaughan, Sue +6 more
core +5 more sources
Antigenic variation in the African trypanosome: molecular mechanisms and phenotypic complexity [PDF]
, 2009 Antigenic variation is an immune evasion strategy that has evolved in viral, bacterial and protistan pathogens. In the African trypanosome this involves stochastic switches in the composition of a variant surface glycoprotein (VSG) coat, using a massive ...
Marcello, Lucio +5 more
core +1 more source
Genome hyperevolution and the success of a parasite [PDF]
, 2012 The strategy of antigenic variation is to present a constantly changing population phenotype that enhances parasite transmission, through evasion of immunity arising within, or existing between, host animals.
J. David Barry +5 more
core +1 more source