Results 21 to 30 of about 10,096 (175)
Trypanosomes at the Gates [PDF]
Science, 2005 L ike many colleagues, I sometimes thought I'd never see the day when three small parasites would be so celebrated. After all, why should people outside of the small cohort of dedicated scientists and sponsors pay any attention to these “Tritryps”— Trypanosoma brucei, Trypanosoma cruzi , and Leishmania major —whose genomes appear in this issue of ...
openaire +2 more sources
Trypanosome diversity in wildlife species from the Serengeti and Luangwa Valley ecosystems [PDF]
, 2012 <p>Background: The importance of wildlife as reservoirs of African trypanosomes pathogenic to man and livestock is well recognised. While new species of trypanosomes and their variants have been identified in tsetse populations, our knowledge of ...
Richard Hoare +47 more
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Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness [PDF]
, 2012 Disruption of glycosylphosphatidylinositol biosynthesis is genetically and chemically validated as a drug target against the protozoan parasite Trypanosoma brucei, the causative agent of African sleeping sickness.
Crossman, Arthur T. +4 more
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Boarder control on the IFT train
eLife, 2014 New details are revealed about the system that transports proteins to the tip of flagella during growth.
Cécile Fort, Philippe Bastin
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Chromosome-wide analysis of gene function by RNA interference in the african trypanosome. [PDF]
, 2006 Trypanosomatids of the order Kinetoplastida are major contributors to global disease and morbidity, and understanding their basic biology coupled with the development of new drug targets represents a critical need.
J. Hayes-Sinclair +23 more
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Insects, 2020 Lotmaria passim currently appears to be the predominant trypanosome in honey bees worldwide. Although, the specific effects of L. passim by single or mixed with other gut parasites such as Nosema ceranae on honey bees’ health is still unclear.
Nolberto Arismendi +5 more
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Trypanosoma irwini n. sp (Sarcomastigophora: Trypanosomatidae) from the koala (Phascolarctos cinereus) [PDF]
, 2009 The morphology and genetic characterization of a new species of trypanosome infecting koalas (Phascolarctos cinereus) are described. Morphological analysis of bloodstream forms and phylogenetic analysis at the 18S rDNA and gGAPDH loci demonstrated this ...
Austen, J. +7 more
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The GTPase IFT27 is involved in both anterograde and retrograde intraflagellar transport
eLife, 2014 The construction of cilia and flagella depends on intraflagellar transport (IFT), the bidirectional movement of two protein complexes (IFT-A and IFT-B) driven by specific kinesin and dynein motors.
Diego Huet +3 more
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Parasite, 2020 This study aimed to identify trypanosomes infecting cattle in Malawi in order to understand the importance of cattle in the transmission dynamics of Human African Trypanosomiasis (HAT) and Animal African Trypanosomosis (AAT).
Marsela Megasari +8 more
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Trypanosome motion represents an adaptation to the crowded environment of the vertebrate bloodstream [PDF]
, 2012 Blood is a remarkable habitat: it is highly viscous, contains a dense packaging of cells and perpetually flows at velocities varying over three orders of magnitude. Only few pathogens endure the harsh physical conditions within the vertebrate bloodstream
Timothy Krüger +46 more
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