Trypanosome Glycosylphosphatidylinositol Biosynthesis [PDF]
Trypanosoma brucei, a protozoan parasite, causes sleeping sickness in humans and Nagana disease in domestic animals in central Africa. The trypanosome surface is extensively covered by glycosylphosphatidylinositol (GPI)-anchored proteins known as variant surface glycoproteins and procyclins.
Yeonchul, Hong, Taroh, Kinoshita
openaire +2 more sources
Functional mapping of a trypanosome centromere by chromosome fragmentation identifies a 16-kb GC-rich transcriptional "strand-switch" domain as a major feature. [PDF]
Trypanosomatids are an ancient family that diverged from the main eukaryotic lineage early in evolution, which display several unique features of gene organization and expression.
Bromley, Elizabeth V +4 more
core +1 more source
PCV correlation between trypanosome species according to thresholds.
PCV correlation between trypanosome species according to thresholds.
Richard Gashururu S. (11841189) +11 more
core +1 more source
Great-tailed grackles (Quiscalus mexicanus) have dramatically expanded into North America over the past century. However, little is known about the blood that parasites they support.
Andrew J. Golnar +5 more
doaj +1 more source
Novel trypanosome Trypanosoma gilletti sp. (Euglenozoa: Trypanosomatidae) and the extension of the host range of Trypanosoma copemani to include the koala (Phascolarctos cinereus) [PDF]
Trypanosoma irwini was previously described from koalas and we now report the finding of a second novel species, T. gilletti, as well as the extension of the host range of Trypanosoma copemani to include koalas.
J. HANGER +12 more
core +1 more source
Glossina spp. gut bacterial flora and their putative role in fly-hosted trypanosome development
Human African trypanosomiasis is caused by trypanosomes transmitted to humans by the tsetse fly, in which they accomplish their development into their infective metacyclic form. The crucial step in parasite survival occurs when it invades the fly midgut.
Anne eGeiger +3 more
doaj +1 more source
The CAF1-NOT complex of trypanosomes [PDF]
In African trypanosomes, there is no control of transcription initiation by RNA polymerase II at the level of individual protein-coding genes. Transcription is polycistronic, and individual mRNAs are excised by trans-splicing and polyadenylation. As a consequence, trypanosomes are uniquely reliant on post-transcriptional mechanisms for control of gene ...
Erben, Esteban +2 more
openaire +3 more sources
The global stability analysis represents a compound failure, mechanism which provides lower calculated factors of safety. In this research, the global stability analysis was used to propose a mathematically model of the transmission dynamics and control
K.M. Bello +4 more
doaj +1 more source
Predicting Mammal Species Suitable for Chagas Disease Spread Using a Machine‐Learning Framework
Chagas disease is maintained in wildlife by Trypanosoma cruzi cycling among many mammal species, but we still do not know the full range of potential hosts. Using machine learning and ecological/behavioral traits, we found that kissing bugs overlap with 573 mammal species and tend to feed on mammals that are den‐dwelling, medium‐to‐large in size, and ...
Maya Rocha‐Ortega +3 more
wiley +1 more source
Advances and challenges in the diagnosis of human and animal african trypanosomiases
Human African trypanosomiasis (HAT) is a life-threatening vector-borne disease caused by parasites of the Trypanosoma brucei spp. HAT incidence has declined in recent years thanks to sustained control efforts, and 10 countries have already achieved ...
Elena Pérez-Antón +4 more
doaj +1 more source

