Results 51 to 60 of about 32,265 (203)
Monitoring the elimination of human African trypanosomiasis: Update to 2014
Background The World Health Organization (WHO) has targeted the elimination of Human African trypanosomiasis (HAT) ‘as a public health problem’ by 2020.
J. Franco +7 more
semanticscholar +1 more source
Tabanus tenens identified in this study is a newly recorded species in Thailand. DNA barcoding using the cox1 gene identified tabanid species in the present study. WGM data from different sites served as a reference for species identification. Abstract Tabanid flies are gaining high medical and veterinary importance due to their role as a vector of ...
Nantatchaporn Klaiklueng +4 more
wiley +1 more source
Toward the elimination of HAT in Nigeria: leaving no community behind
Objectives: Sleeping sickness, also known as human African trypanosomiasis (HAT), is a tsetse fly-borne neglected tropical disease that affects underserved rural communities in sub-Saharan Africa.
Rolayo T. Emmanuel +2 more
doaj +1 more source
La presente comunicación reporta los valores de las enzimas transaminasas, Aspartatoaminotransferasa (AST) y Alaninaaminotransferasa (ALT) encontrados en sueros de cabras infectadas con la cepa de Trypanosoma vivax Stock (TvIIV) y sus controles.
Emir Espinoza, Gisela Primera
doaj +1 more source
Trypanosomiasis, caused by Trypanosoma vivax, is responsible for great economic losses among livestock in Africa and South America. During the life cycle of these parasites, they may present different morphological, metabolic and physiological ...
Rosangela Zacarias Machado +11 more
doaj +1 more source
Targeting Expanded CUG and CTG Repeats as a Therapeutic Approach for Myotonic Dystrophy Type 1 (DM1)
DM1 is an RNA gain‐of‐function disease caused by CTG repeat expansion, producing toxic r(CUG)exp RNA that sequesters MBNL1 and impairs splicing. This review covers the field of CUG and CTG ligands identified or rationally designed as DM1 drug candidates, highlighting their molecular design, RNA‐ or DNA‐binding modes, in vitro affinities and ...
Camille Richagneux, Anton Granzhan
wiley +1 more source
Epidemiology, diagnosis, and treatment of one of the world’s most neglected ...
R. Brun, J. Blum, F. Chappuis, C. Burri
semanticscholar +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Melarsoprol Resistance in African Trypanosomiasis.
Arsenicals were introduced as monotherapies for the treatment of human African trypanosomiasis, or sleeping sickness, over 100 years ago. Toxicity has always been an issue but these drugs have proven to be both effective and quite durable. Unfortunately,
A. Fairlamb, D. Horn
semanticscholar +1 more source
Human African trypanosomiasis (HAT), commonly known as sleeping sickness, remains a significant health threat in sub-Saharan Africa. In Nigeria, the challenges of diagnosing and treating HAT are profound, especially in resource-constrained, remote areas.
Kelly Zongo, Rolayo Toyin Emmanuel
doaj +1 more source

