Results 31 to 40 of about 8,341 (178)

The first five-year evaluation of cystic fibrosis neonatal screening program in São Paulo State, Brazil [PDF]

open access: yesCadernos de Saúde Pública, 2020
The Hospital of the Ribeirão Preto Medical School, University of São Paulo is one of the three screening centers in São Paulo State, Brazil, and has included a test for cystic fibrosis (CF) since February 6, 2010, by a court order. We evaluated the first
Léa Maria Zanini Maciel   +8 more
doaj   +1 more source

Hereditary chronic pancreatitis

open access: yesOrphanet Journal of Rare Diseases, 2007
Hereditary chronic pancreatitis (HCP) is a very rare form of early onset chronic pancreatitis. With the exception of the young age at diagnosis and a slower progression, the clinical course, morphological features and laboratory findings of HCP do not ...
Mössner Joachim   +3 more
doaj   +1 more source

Patients With Pancreatitis‐Related Gene Variants Showed Higher Incidence of Hyperpancreatic Enzymemia After Endoscopic Retrograde Cholangiopancreatography

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
Pancreatitis‐related gene variants are associated with a higher incidence of post‐ERCP hyperpancreatic enzymemia, whereas no significant association is observed with post‐ERCP pancreatitis. These findings suggest that genetic background contributes to early biochemical pancreatic injury after ERCP and may help identify patients with increased ...
Daishi Kabemura   +16 more
wiley   +1 more source

Insect‐resistant soybean genotypes accumulate rutin and its O‐methylated derivative narcissin, a more potent flavonol targeting Anticarsia gemmatalis digestive and detoxification enzymes and reducing larval survival

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 10, Page 5921-5933, 15 August 2026.
Abstract BACKGROUND Soybean underpins Brazil's agricultural, yet its sustainability is threatened by lepidopteran pests such as Anticarsia gemmatalis. Although insect‐resistant cultivars have long been associated with the constitutive accumulation of quercetin‐derived flavonols, the biochemical mechanisms underlying this resistance remain poorly ...
Jessica Nunes de Assis   +9 more
wiley   +1 more source

Extensive Molecular Analysis Suggested the Strong Genetic Heterogeneity of Idiopathic Chronic Pancreatitis

open access: yesMolecular Medicine, 2016
Genetic features of chronic pancreatitis (CP) have been investigated extensively, mainly by testing genes associated to the trypsinogen activation pathway.
Valentina Maria Sofia   +15 more
doaj   +1 more source

Cystic fibrosis diagnosed by state newborn screening: Or is it?

open access: yesSAGE Open Medical Case Reports, 2020
Newborn screening for cystic fibrosis is universal across the United States; however, each state chooses the method by which they screen. Illinois employs a two-step process which includes the measurement of the immunoreactive trypsinogen followed by an ...
Maura Fox   +3 more
doaj   +1 more source

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

open access: yesChemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

Structural and Hormonal Changes Associated With Starvation in Zambian Adult Patients With Esophageal Strictures: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Malnutrition disorders are associated with an enteropathy characterized by villus blunting, secretory cell loss, and mucosal inflammation. To investigate the contribution of undernutrition to enteropathy we conducted a case–control study of adult patients with starvation due to benign esophageal strictures, compared with ...
Ellen Besa   +7 more
wiley   +1 more source

Dissipatively Fueled Unidirectionally Communicating DNA Circuits That Control Biocatalysis

open access: yesAngewandte Chemie, Volume 138, Issue 17, 20 April 2026.
Unidirectionally communicating, out‐of‐equilibrium DNA circuits are used to control enzyme activity. Transient DNAzyme activation generates fuel for temporal trypsin activation. Cyclic fuel‐driven hybridization and exonuclease‐mediated reset enable precise control over lifetimes, which is analyzed using combined experimental and computational ...
Philippe Jung   +6 more
wiley   +2 more sources

Framework for interpretation of trypsin-antitrypsin imbalance and genetic heterogeneity in pancreatitis

open access: yesThe Saudi Journal of Gastroenterology, 2015
Early intracellular premature trypsinogen activation was interpreted as the key initiator of pancreatitis. When the balance in the homeostasis of trypsin and antitrypsin system is disequilibrated, elevated aggressive enzymes directly attack the ...
Kun Lin   +4 more
doaj   +1 more source

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