Chemical Composition and Biological Activities of <i>Psilocybe</i> Mushrooms: Gaps and Perspectives. [PDF]
Pharmaceuticals (Basel)The Psilocybe genus is known for producing tryptamine alkaloids, specifically the compounds psilocybin and psilocin, which have shown antidepressant and anxiolytic potential.
Luz MA +10 more
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A sustainable protocol for the synthesis of N-acyl tryptamines, a class of potential gut microbiota-derived endocannabinoid-like mediators. [PDF]
Front ChemA simple and sustainable propylphosphonic anhydride (T3P)-assisted methodology for the synthesis of N-acyl tryptamines, an interesting class of gut microbiota-derived endocannabinoid-like lipid mediators, was proposed.
Villano R, Di Marzo V.
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Hallucinogen use in the United States, 2021–2023: Diverging trends and subgroup patterns [PDF]
Drug Alcohol Depend RepBackground: While interest in the therapeutic and recreational use of hallucinogens has increased, national surveillance often reports use in aggregate, potentially masking shifting trends among pharmacologically distinct substances.
Chen J, Berg C, Yang Y.
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Psychedelics and ketamine/esketamine in depressive disorders: biological mechanisms and associated neuroimaging and clinical changes. [PDF]
Transl PsychiatryBackground Over the past ten years, several psychedelic compounds, including tryptamines like lysergic acid diethylamide/LSD, psilocybin, ayahuasca, and dimethyltryptamine/DMT, have been tested in clinical trials for a range of psychiatric conditions ...
d'Andrea G +15 more
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Determination of Three Types of New Psychoactive Tryptamines in Blood by QuEChERS Combined with UPLC-MS/MS [PDF]
Fayixue Zazhi, 2021 Objective To establish a method combining QuEChERS and ultra-high liquid chromatography-tandem mass spectrometry （UPLC-MS/MS） for rapid screening and testing of three types of new psychoactive tryptamines in human blood： 5-MeO-DALT, 5-MeO-MiPT and 5-MeO ...
HOU Wei, WANG Yan-yan, ZHANG Ying, et al.
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Talanta Open, 2023 Tryptamines are a class of new psychoactive substances relevant for analysis in forensic laboratories. Tryptamine analogs are diverse in structure and chemical properties, and prone to display instability.
Maria Schüller +4 more
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IUCrData, 2021 The title compound, 5-hydroxy-N,N,N-trimethyltryptammonium (5-HTQ) iodide {systematic name: [2-(5-hydroxy-1H-indol-3-yl)ethyl]trimethylazanium iodide}, C13H19N2O+·I−, has a single tryptammonium cation and one iodide anion in the asymmetric unit. The ions
Duyen N. K. Pham +3 more
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Effects of psychedelics on neurogenesis and broader neuroplasticity: a systematic review. [PDF]
Mol MedIn the mammalian brain, new neurons continue to be generated throughout life in a process known as adult neurogenesis. The role of adult-generated neurons has been broadly studied across laboratories, and mounting evidence suggests a strong link to the ...
Lima da Cruz RV, Leão RN, Moulin TC.
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Bis(4-acetoxy-N-ethyl-N-n-propyltryptammonium) fumarate–fumaric acid (1/1)
IUCrData, 2023 The solid-state structure of the title salt/adduct (systemic name: bis{[2-(4-acetyloxy-1H-indol-3-yl)ethyl](ethyl)propylazanium} but-2-enedioate–(E)-butenedioic acid (1/1)), 2C17H25N2O2+·C4H2O42−·C4H4O4, was determined by single-crystal X-ray diffraction.
Duyen N. K. Pham +4 more
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A Review of Synthetic Access to Therapeutic Compounds Extracted from Psilocybe
Pharmaceuticals, 2022 Psychedelics are used for various pathologies of the central nervous system and are currently the subject of much research, some of which relates to the compounds contained in various Psilocybe-type hallucinogenic mushrooms.
Raphaël Serreau +3 more
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