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2022
Tryptamine (2-(1H-indol-3-yl)ethan-1-amine) is a naturally-occurring metabolite of the amino acid tryptophan, which, in turn, is a constituent of many proteins. Although tryptamine has few significant pharmacological properties, it forms the parent nucleus of a number of hallucinogenic drugs. Some of these tryptamines are derived from plant material or
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Tryptamine (2-(1H-indol-3-yl)ethan-1-amine) is a naturally-occurring metabolite of the amino acid tryptophan, which, in turn, is a constituent of many proteins. Although tryptamine has few significant pharmacological properties, it forms the parent nucleus of a number of hallucinogenic drugs. Some of these tryptamines are derived from plant material or
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The Ten Proaporphine-tryptamine Dimers
Journal of Natural Products, 1990Turkish Roemeria hybrida produces ten proaporphine-tryptamine dimers, two of which, (–)-roehybridine [1] and (–)-roemeridine [8], were previously known. The dimers have been divided into three subgroups based on the stereochemistry at C-9 and at the spiro C-10 center.
Gözler B., Freyer A.J., Shamma M.
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Identification and Distribution of Tryptamine in the Rat
Canadian Journal of Biochemistry, 1974A procedure for the quantitative measurement of tryptamine in mammalian tissues is described. The amine is isolated by ion-exchange chromatography, converted to its dansyl derivative, further purified by thin-layer chromatography, and quantitated by the mass-spectrometric integrated ion current technique using an isotopically labelled internal ...
S R, Philips, D A, Durden, A A, Boulton
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Conformational Relaxation Paths in Tryptamine
The Journal of Physical Chemistry A, 2008The relative fluorescence intensities of three conformers of tryptamine have been determined as a function of stagnation pressure and nozzle temperature in a supersonic expansion. The relative intensities of the conformers that are connected by different direct and indirect interconversion paths on the potential-energy hypersurface differ considerably ...
Marcel, Böhm +3 more
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Benzofuran bioisosteres of hallucinogenic tryptamines
Journal of Medicinal Chemistry, 1992The benzofuran analogues of the hallucinogens 5-methoxy-N,N-dimethyltryptamine and 5-methoxy-alpha-methyltryptamine were synthesized and evaluated for affinity at the serotonin 5-HT2 and 5-HT1A receptors in rat brain homogenate, labeled with [125I]-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane ([125I]DOI) and [3H]-8-hydroxy-2-(N,N-di-n-propylamino ...
Z, Tomaszewski +3 more
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Palladium-catalyzed synthesis of tryptamines and tryptamine homologues: synthesis of psilocin
Tetrahedron, 2009A new Pd-catalyzed method for the synthesis of tryptamines is developed, and its applications to the synthesis of Corey's aspidophytine tryptamine 15 and psilocin 20 are also described.
Chunmei Hu +3 more
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Psychoactive tryptamines from basidiomycetes
Folia Microbiologica, 2002The review lists natural sources, i.e. strains and species of fungi producing predominantly psychoactive tryptamines (indolealkylamines), their chemical structure and properties, toxic effects on the man and psychic symptoms of intoxication. It describes the biosynthesis and production of some tryptamines by the mycelial culture of Psilocybe bohemica ...
M, Wurst, R, Kysilka, M, Flieger
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THE PHARMACOLOGY OF TRYPTAMINE
Australian Journal of Experimental Biology and Medical Science, 1951openaire +2 more sources