Results 141 to 150 of about 2,854 (189)
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N-Alkylation of phenethylamine and tryptamine

Bioorganic & Medicinal Chemistry Letters, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Gerta, Cami-Kobeci   +3 more
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Effects of infused tryptamine in man

Psychopharmacologia, 1970
Tryptamine, infused intravenously in man, facilitates the patellar reflex, dilates pupils and elevates blood pressure. It also causes changes in vision and hearing, as well as nausea, vomiting, dizziness, sweating and heaviness of body. These changes are similar to those produced by LSD-like hallucinogens and are consistent with the hypothesis that LSD-
W R, Martin, J W, Sloan
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Tryptamines and Lysergamides

2022
Tryptamine (2-(1H-indol-3-yl)ethan-1-amine) is a naturally-occurring metabolite of the amino acid tryptophan, which, in turn, is a constituent of many proteins. Although tryptamine has few significant pharmacological properties, it forms the parent nucleus of a number of hallucinogenic drugs. Some of these tryptamines are derived from plant material or
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The Ten Proaporphine-tryptamine Dimers

Journal of Natural Products, 1990
Turkish Roemeria hybrida produces ten proaporphine-tryptamine dimers, two of which, (–)-roehybridine [1] and (–)-roemeridine [8], were previously known. The dimers have been divided into three subgroups based on the stereochemistry at C-9 and at the spiro C-10 center.
Gözler B., Freyer A.J., Shamma M.
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Identification and Distribution of Tryptamine in the Rat

Canadian Journal of Biochemistry, 1974
A procedure for the quantitative measurement of tryptamine in mammalian tissues is described. The amine is isolated by ion-exchange chromatography, converted to its dansyl derivative, further purified by thin-layer chromatography, and quantitated by the mass-spectrometric integrated ion current technique using an isotopically labelled internal ...
S R, Philips, D A, Durden, A A, Boulton
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Conformational Relaxation Paths in Tryptamine

The Journal of Physical Chemistry A, 2008
The relative fluorescence intensities of three conformers of tryptamine have been determined as a function of stagnation pressure and nozzle temperature in a supersonic expansion. The relative intensities of the conformers that are connected by different direct and indirect interconversion paths on the potential-energy hypersurface differ considerably ...
Marcel, Böhm   +3 more
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Benzofuran bioisosteres of hallucinogenic tryptamines

Journal of Medicinal Chemistry, 1992
The benzofuran analogues of the hallucinogens 5-methoxy-N,N-dimethyltryptamine and 5-methoxy-alpha-methyltryptamine were synthesized and evaluated for affinity at the serotonin 5-HT2 and 5-HT1A receptors in rat brain homogenate, labeled with [125I]-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane ([125I]DOI) and [3H]-8-hydroxy-2-(N,N-di-n-propylamino ...
Z, Tomaszewski   +3 more
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Psychoactive tryptamines from basidiomycetes

Folia Microbiologica, 2002
The review lists natural sources, i.e. strains and species of fungi producing predominantly psychoactive tryptamines (indolealkylamines), their chemical structure and properties, toxic effects on the man and psychic symptoms of intoxication. It describes the biosynthesis and production of some tryptamines by the mycelial culture of Psilocybe bohemica ...
M, Wurst, R, Kysilka, M, Flieger
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Palladium-catalyzed synthesis of tryptamines and tryptamine homologues: synthesis of psilocin

Tetrahedron, 2009
A new Pd-catalyzed method for the synthesis of tryptamines is developed, and its applications to the synthesis of Corey's aspidophytine tryptamine 15 and psilocin 20 are also described.
Chunmei Hu   +3 more
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Selective Introduction of TMS Groups in Tryptamines: Preparation of N1-TMS Derivatives of Tryptamines

Journal of Chromatographic Science, 1977
Indolethylamines (tryptamines) with a primary animofunction react with Regisil under controlled conditions to yield a mono TMS derivative. Mass spectrometry to these derivatives shows that the TMS group is substituted on the indolic nitrogen (N1) and not the primary amino nitrogen. This is confirmed by converting these compounds to their isothiocyanate
N, Narasimhachari, K, Leiner
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