Results 151 to 160 of about 3,690 (207)

Mass spectrometry of tryptamines and acetylated tryptamine derivatives

Analytical Biochemistry, 1972
Abstract Eleven mass spectra of biologically important tryptamines and their acetylated derivatives are recorded in this paper. For diagnostic purposes, the N -acetyltryptamines are preferred over other derivatives because they undergo the fewest significant rearrangements upon electron impact.
M W, Couch, C M, Williams
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Tryptamine Metabolism in Depression

British Journal of Psychiatry, 1965
In a previous investigation we showed that large doses of DL-tryptophan (214 mg./kg. body weight) given to depressed patients receiving tranylcypromine (a monoamine oxidase inhibitor) potentiated the antidepressive effects of the drug (Coppen, Shaw and Farrell, 1963). This procedure increases the level of brain 5-hydroxytryptamine (5 HT) and tryptamine
A, Coppen, D M, Shaw, A, Malleson, E, Eccleston, G, Gundy   +4 more
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Tryptamine and Serotonin Receptors

Nature, 1962
A RECENT communication by Vane et al. entitled “Tryptamine Receptors in the Central Nervous System”1 concluded, on the basis of indirect evidence, that the receptors for tryptamine and for serotonin (5-hydroxytryptamine) were the same. Because the authors neglected to mention some earlier evidence of a more direct kind which showed clearly that certain
D W, WOOLLEY, E, SHAW
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Tryptamine in the vertebrate lens

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1983
Abstract The normal ionic balance and transparency of the lens is regulated by Na + −K + pumps in the lens epithelium and lens fibers. Inhibition of the (Na + +K + )-ATPase and ion transport results in osmotic swelling and opacification. We have previously shown that 10 −4 –10 −3 M tryptamine has an inhibitory effect on both ion transport and ...
O A, Candia, L J, Alvarez, P A, Lanzetta, P, Cook   +3 more
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Brain levels of tryptamine

Psychopharmacologia, 1972
A modification of the method of Hess and Udenfriend (1959) for the extraction and identification of tryptamine, as well as a gas chromatographic method for identifying tryptamine, has been described. Tryptamine, using these methods, as well as thin layer chromatography, has been identified in steer, dog and human brain.
W R, Martin, J W, Sloan, S T, Christian, T H, Clements   +3 more
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Photoinduced processes in protonated tryptamine

The Journal of Chemical Physics, 2005
The electronic excited state dynamics of protonated tryptamine ions generated by an electrospray source have been studied by means of photoinduced dissociation technique on the femtosecond time scale. The result is that the initially excited state decays very quickly within 250fs.
Kang, H., Jouvet, C., Dedonder-Lardeux, C., Martrenchard, S., Charriere, C., Grégoire, G., Desfrançois, C., Schermann, J.P., Barat, M., Fayeton, J.A.   +9 more
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Catecholamines and Tryptamines

1969
Catecholamines are represented in the vertebrate nervous system most notably by noradrenaline (NA) and dopamine (DA), but also by the precursor compounds and related ones. Tryptamines are represented primarily by 5-hydroxytryptamine (5-HT or serotonin), but tryptamine itself has been detected there as well.
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N-Alkylation of phenethylamine and tryptamine

Bioorganic & Medicinal Chemistry Letters, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Gerta, Cami-Kobeci, Paul A, Slatford, Michael K, Whittlesey, Jonathan M J, Williams   +3 more
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An analytical perspective on favoured synthetic routes to the psychoactive tryptamines

Journal of Pharmaceutical and Biomedical Analysis, 2004
Many tryptamine derivatives are known to induce altered states of consciousness and are increasingly of interest in forensic and neurobiological studies. The analytical chemistry of certain synthetic routes to the tryptamines is discussed and likely side
Simon D. Brandt, Sally Freeman, John F Alder   +2 more
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Effects of infused tryptamine in man

Psychopharmacologia, 1970
Tryptamine, infused intravenously in man, facilitates the patellar reflex, dilates pupils and elevates blood pressure. It also causes changes in vision and hearing, as well as nausea, vomiting, dizziness, sweating and heaviness of body. These changes are similar to those produced by LSD-like hallucinogens and are consistent with the hypothesis that LSD-
W R, Martin, J W, Sloan
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