Results 81 to 90 of about 21,184 (241)
Cutaneous manifestations in Hymenoptera and Diptera anaphylaxis: relationship with basal serum tryptase [PDF]
, 2009 ObjectivesTo compare the clinical presentation of systemic anaphylaxis to Hymenoptera and Diptera with regard to basal serum tryptase (BT) and to evaluate mastocytosis in patients with elevated tryptase.
Chappard, Daniel +13 more
core +1 more source
The fight of innate immunity and abnormal cannabinoids against Candida infection
British Journal of Pharmacology, EarlyView.Candida species represent the most clinically significant fungal pathogens in humans, with invasive candidiasis carrying a mortality of 30%–40% in critically ill patients despite modern antifungal therapy. The innate immune system – through the coordinated and specific activities of neutrophils, macrophages, NK cells, mast cells and eosinophils ...
Prince Ofori +2 more
wiley +1 more source
Immunostaining of ERM for tryptase and chymase.
, 2019 The ERM stained weakly positive for both tryptase and chymase, and double-positive cells for tryptase and chymase were sparsely obtained.
Seita Morishita (505170) +9 more
core +1 more source
Involvement of premacular mast cells in the pathogenesis of macular diseases.
PLoS ONE, 2019 We previously reported on the elevated intravitreal activities of tryptase and chymase in association with idiopathic epiretinal membrane (ERM) and idiopathic macular hole (MH).
Takaki Sato +9 more
doaj +1 more source
A case of an elevated tryptase
, 2022 Introduction: Hereditary Alpha Tryptasemia (HαT) is an autosomal dominant disorder characterized by an elevated baseline tryptase that occurs up to 3% of the population and clinically resembles mast cell activation syndrome. Case description: A full-term,
Parashar, Sonya
core
Cells, 2019 Mast cells contain large amounts of proteases stored within their secretory granules. Previously we showed that one of these proteases, tryptase, in addition to its location within granules, can also be found within the mast cell nucleus, where it has ...
Sebastin Santosh Martin +2 more
doaj +1 more source
Clinical &Experimental Allergy, EarlyView.Tryptase locus variation explains normal‐range baseline serum tryptase differences and is associated with Hymenoptera venom anaphylaxis, independent of clonal mast cell disease and HαT. ABSTRACT Background Increased basal serum tryptase level (BST) is associated with anaphylaxis.
Manca Svetina +6 more
wiley +1 more source
Co-localization of tryptase and cathepsin-G in mast cells in cutaneous mastocytosis
, 2009 Mastocytosis is a heterogeneous disease characterized by an abnormal growth and/or accumulation of clonal mast cells (MC) in one or more organs. The most frequent site of organ involvement is the skin.
FINATO, Nicoletta +9 more
core +1 more source
Mast cell tryptase induces nuclear remodelling and reduced growth in breast cancer cells
Cell Death DiscoveryMast cells accumulate in breast cancer, but there is only limited knowledge of how they impact on breast cancer growth. Here we show that tryptase, a major compound stored in mast cell secretory granules, has profound effects on breast cancer cell ...
Filip Pano +6 more
doaj +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley +1 more source