Results 11 to 20 of about 1,553 (208)

Expression of mast cell proteases correlates with mast cell maturation and angiogenesis during tumor progression. [PDF]

PLoS ONE, 2012
Tumor cells are surrounded by infiltrating inflammatory cells, such as lymphocytes, neutrophils, macrophages, and mast cells. A body of evidence indicates that mast cells are associated with various types of tumors.
Devandir Antonio de Souza, Vanina Danuza Toso, Maria Rita de Cássia Campos, Vanessa Soares Lara, Constance Oliver, Maria Célia Jamur   +5 more
doaj   +1 more source

Different levels of mucus inflammatory mediators in nasal polyposis with and without aeroallergen sensitivity

Laryngoscope Investigative Otolaryngology, 2022
Objectives Biomarker levels in nasal secretions can reflect the inflammatory status of nasal mucosa and evolution of sinus disease. The aim of this study was to evaluate the relationship between local inflammatory mediator production and clinical ...
Aleksandar Dimić, Aleksandar Perić, Uglješa Grgurević, Jelena Sotirović, Milica Labus, Nenad Baletić, Milanko Milojević, Ivan Stanojević, Danilo Vojvodić   +8 more
doaj   +1 more source

Histamine Is Responsible for the Neuropathic Itch Induced by the Pseudorabies Virus Variant in a Mouse Model

Viruses, 2022
Pseudorabies virus (PRV) is the causative agent of pseudorabies (PR). It can infect a wide range of mammals. PRV infection can cause severe acute neuropathy (the so-called “mad itch”) in nonnatural hosts. PRV can infect the peripheral nervous system (PNS)
Bing Wang, Hongxia Wu, Hansong Qi, Hanglin Li, Li Pan, Lianfeng Li, Kehui Zhang, Mengqi Yuan, Yimin Wang, Hua-Ji Qiu, Yuan Sun   +10 more
doaj   +1 more source

Immunoelectron microscopy study of superficial skin nerves in drug-induced acute urticaria Estudo de microscopia imunoeletrônica dos nervos superficiais da pele na urticária aguda induzida por medicamentos

Anais Brasileiros de Dermatologia, 2012
BACKGROUND: Few studies have evaluated the ultrastructure of the superficial skin nerves in urticaria. OBJECTIVE: The objective of this study was to describe findings in superficial skin nerves in cases of drug-induced acute urticaria.
Paulo Ricardo Criado, Roberta Fachini Jardim Criado, Cleusa F.H. Takakura, Carla Pagliari, Mirian Nacagami Sotto, Cidia Vasconcellos   +5 more
doaj   +1 more source

Immune responses in fatalities involving opioids

Forensic Sciences Research, 2019
In some cases of fatalities involving opioid use, the concentrations of detected opioids are not in the toxic range. Immune reactions can be triggered by opioid use, suggesting that immune response may be a factor in these cases.
Henry J. Carson
doaj   +1 more source

Mast cell β tryptases and articular cartilage aggrecanolysis [PDF]

, 2013
Increased quantities of the mast cell (MC)-restricted β tryptase, mouse MC protease (mMCP)-6 and its human ortholog hTryptase-β are present in the synovial tissue of mouse and human arthritic joints.
Magarinos, Natalia
core   +1 more source

Relationship between Tryptase and Type 2 Diabetes Mellitus with Macrovascular Complications: a Ten-year Follow-up Study [PDF]

Zhongguo quanke yixue
Background Diabetic macrovascular complications represent prevalent and severe consequences of diabetes mellitus, characterized by high morbidity and significant clinical impact. To date, the pathogenesis of the disease remains undefined.
ZHAO Ya, WAN Qin
doaj   +1 more source

Effect of tryptase inhibition on joint inflammation: a pharmacological and lentivirus-mediated gene transfer study

Arthritis Research & Therapy, 2017
Background Increasing evidences indicate that an unbalance between tryptases and their endogenous inhibitors, leading to an increased proteolytic activity, is implicated in the pathophysiology of rheumatoid arthritis.
Alexandre Denadai-Souza, Camilla Moreira Ribeiro, Corinne Rolland, Anne Thouard, Céline Deraison, Cristoforo Scavone, Daniel Gonzalez-Dunia, Nathalie Vergnolle, Maria Christina Werneck Avellar   +8 more
doaj   +1 more source

Mast cell tryptases induce an increase of angiogenesis in chicken chorioallantoic membrane.

, 2015
When compared to the control CAM (no tryptases), CAM incubated in presence of rmMCP-6 and 7 showed an increase in the number of blood vessels. Moreover, an increase in blood vessel caliber was also seen in the presence of the tryptases.
Maria Célia Jamur (79424), Devandir Antonio de Souza Junior (833396), Constance Oliver (35853), Antonio Carlos Borges (833397), Ana Carolina Santana (833398)   +4 more
core   +1 more source

Tryptase genetics and anaphylaxis [PDF]

Journal of Allergy and Clinical Immunology, 2006
Tryptases secreted by tissue mast cells and basophils can enter the bloodstream. In human subjects tryptases are encoded by several genes and alleles, including alpha, beta, gamma, and delta. Common variations include complete absence of alpha genes.
openaire   +2 more sources