Results 31 to 40 of about 1,553 (208)
iMetaMed, EarlyView.Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang +10 more
wiley +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Artificial Intelligence is rapidly transforming allergology by enhancing diagnosis, risk prediction, automation, patient communication, education, and therapy development. Machine learning approaches, including convolutional neural networks, recurrent architectures, and transformer‐based models, enable analysis of complex datasets from ...
Sebastian Seurig +2 more
wiley +1 more source
Cloning, Recombinant Production and Charcterization of Human Mast Cell Tryptases [PDF]
, 2007 Tryptasen sind tetramere Trypsin-ähnliche Serinproteasen die aus den sekretorischen Granula von Mastzellen freigesetzt werden. Sie scheinen an der Pathogenese von chronisch entzündlichen Erkrankungen wie Asthma beteiligt zu sein.
Zettl, Frank
core
Mast cell tryptase, a still enigmatic enzyme
, 2004 Tryptases constitute a subfamily of trypsin-like proteinases, stored in the mast cell secretory granules of all mammalian organisms. These enzymes are released along with other mediators into the extracellular medium upon mast cell activation ...
FIORUCCI, LAURA, Ascoli, F.
core +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT This study aimed to elucidate the role of the RNA‐binding protein embryonic lethality abnormal vision‐like protein 1 (ELAVL1) in the pathogenesis of allergic rhinitis (AR), specifically by investigating its potential to promote T helper 2 (Th2) cell differentiation by regulating the stability of carboxypeptidase A3 (CPA3) mRNA.
Meng‐Ya Liu +2 more
wiley +1 more source
Expression of a Mast Cell Tryptase in the Human Monocytic Cell Lines U‐937 and Mono Mac 6
, 1993 Expression of a mast cell tryptase mRNA was detected in two human monocytic cell lines, the U-937 and the Mono Mac 6, and in normal human peripheral blood(PB) monocytes.
Larsson, Lars-Gunnar, +15 more
core +1 more source
The roles of beta and alpha tryptases in asthma: genetic and immunopharmacological studies
, 2010 Tryptases, the dominant secretory granular proteins from human mast cells, are emerging as important mediators in asthma and allergy. The β- and α- tryptases have highly similar nucleotide sequences and located on the same locus.
Abdelmotelb, Ahmed Asem Mahrous
core +1 more source
Inducible Laryngeal Obstruction in Hypermobile Patients
The Laryngoscope, EarlyView.Patients with hypermobile Ehlers‐Danlos syndrome (hEDS) or hypermobility spectrum disorders (HSD) who screened positive for inducible laryngeal obstruction (ILO) reported significantly greater voice, cough, swallowing, gastrointestinal, and mast cell‐related symptoms than those without ILO. Chronic cough, dysphagia, and elevated mast cell symptom score
Stacey M. Menton +10 more
wiley +1 more source
, 2015 The graph shows the cytokines/proteins that were released exclusively by rmMCP-6 (blue) or rmMCP-7 (red). Four cytokines/proteins that were released by control cells were increased in the presence of the tryptases (green).
Maria Célia Jamur (79424) +4 more
core +1 more source
A 17 year experience in perioperative anaphylaxis 1998-2015: harmonising optimal detection of mast cell mediator release. [PDF]
, 2016 BACKGROUND: Sheffield NARCOS (National Adverse Reactions Advisory Service) investigates suspected perioperative anaesthetic reactions using serial tryptase, urinary methylhistamine and clinical information.
A. Shrimpton +9 more
core +1 more source