Results 161 to 170 of about 436,973 (328)

H2S Is a Potential Universal Reducing Agent for Prx6‐Type Peroxiredoxins

open access: yesAdvanced Science, EarlyView.
We report the identification of H2S as reducing agent for Prx6‐type peroxiredoxins. In contrast to common physiological reducing agents of other peroxiredoxins, HS− is small enough to access the active site of oxidized Prx6‐type enzymes in the fully‐folded protein conformation.
Lukas Lang   +3 more
wiley   +1 more source

TRYPTOPHANE STUDIES [PDF]

open access: yesJournal of Biological Chemistry, 1946
J. de la Huerga   +2 more
openaire   +2 more sources

Hepatic CBP/p300 Orchestrate Amino Acid‐Driven Gluconeogenesis through Histone Crotonylation

open access: yesAdvanced Science, EarlyView.
Hepatic CBP/p300 control amino acid‐driven gluconeogenesis by modulating histone crotonylation. This study identifies 2‐aminoadipate (2‐AAA) as a key metabolite that enhances crotonylation and activates amino acid and gluconeogenic gene expression.
Chunxiang Sheng   +15 more
wiley   +1 more source

Multifunctional Carbon Dots for Electrochemical Capacitors Reviewed: Their Opportunities and Challenges

open access: yesAdvanced Science, EarlyView.
Carbon dots (CDs) with unique natures of small size, high specific surface area, and tunable surface functional groups significantly enhance the specific capacitance and cycling stability of electrochemical capacitors (ECs). This review systematically discusses critical challenges and opportunities associated with multifunctional CDs in ECs, aiming to ...
Naiyun Liu   +9 more
wiley   +1 more source

Switchbody, an Antigen‐Responsive Enzyme Switch Based on Antibody and Its Working Principle

open access: yesAdvanced Science, EarlyView.
This paper presents an antibody‐based enzyme switch, termed a “Switchbody”, which is fused with an enzyme‐derived fragment to the N‐terminus of an antibody. As its working principle, the fused fragment is trapped within the antibody and released upon antigen binding, leading to enzyme reconstitution and a subsequent increase in enzyme activity.
Takanobu Yasuda   +10 more
wiley   +1 more source

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