Results 141 to 150 of about 70,579 (241)

Association between circulating tryptophan metabolites and postoperative pain intensity in lumbar disc herniation surgery: An observational study. [PDF]

Medicine (Baltimore)
Celik Y, Aksu H, Gunenc FS, Kalemci O, Kizmazoglu C, Keskinoglu P.   +5 more
europepmc   +1 more source

Host‐driven hepatic conversion of gut microbiota‐derived putrescine to spermidine mediates mannose's protective effects against hepatic steatosis in zebrafish

iMeta, EarlyView.
Evidence for liver metabolism of gut‐derived microbial compounds into beneficial secondary metabolites has been lacking. Here, we demonstrate that Cetobacterium somerae (C. somerae), enriched by mannose supplementation under high‐fat diet conditions, convert arginine into putrescine.
Delong Meng, Zhen Zhang, Tsegay Teame, Benjamin Earl Niemann, Rui Xia, Shichang Xu, Yajie Zhao, Yalin Yang, Chao Ran, Le Luo Guan, Zhigang Zhou   +10 more
wiley   +1 more source

The role of the tryptophan metabolites in gut microbiota-brain axis and potential treatments: a focus on ischemic stroke. [PDF]

Front Pharmacol
Qin N, Xie X, Deng R, Gao S, Zhu T.
europepmc   +1 more source

IL4I1-catalyzed tryptophan metabolites mediate the anti-inflammatory function of cytokine-primed human muscle stem cells. [PDF]

Cell Death Discov, 2023
Zuo M, Fang J, Huang P, Liu S, Hou P, Wang S, Liu Z, Feng C, Cao L, Li P, Shi Y, Shao C.   +11 more
europepmc   +1 more source

Metabolic Signatures and Diagnostic Prediction Models for Coronary Artery Disease and Type 2 Diabetes Mellitus: Insights From an Exploratory Study

iNew Medicine, EarlyView.
Metabolomic & lipidomic analysis reveals metabolic overlap between CAD & T2DM, highlighting 7 key metabolites as potential biomarkers. A predictive model based on these achieves high accuracy, potentially advancing precision medicine & metabolic insights.
Zhihua Wang, Meiming Su, Ying Li, Yapei Li, Shuo Chen, Ting Peng, Hans Strijdom, Jiangang Wang, Jianping Weng, Suowen Xu   +9 more
wiley   +1 more source

Tryptophan metabolites exert potential therapeutic activity in graves' orbitopathy by ameliorating orbital fibroblasts inflammation and proliferation. [PDF]

J Endocrinol Invest
Yang W, Xu X, Xie R, Lin J, Hou Z, Xin Z, Cao X, Shi T.   +7 more
europepmc   +1 more source

Activation of aryl hydrocarbon receptor (AhR) in Alzheimer's disease: role of tryptophan metabolites generated by gut host-microbiota. [PDF]

J Mol Med (Berl), 2023
Salminen A.
europepmc   +1 more source

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

iNew Medicine, EarlyView.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen, Junda Liu, Xixi Chen, Shi Chen, Yuanyuan Tian, Baoming Wu, Fengxia Yan   +6 more
wiley   +1 more source

Association Between the Dutch Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND-NL) Diet Adherence and Systemic Tryptophan Metabolites in Older Adults at Risk of Cognitive Decline: An Exploratory Study. [PDF]

Mol Nutr Food Res
Beers S, de Groot LCPGM, van Loenen MR, Remie LB, Bromhaar MG, Anesi A, Vrhovsek U, Oosterman JM, Aarts E, van Trijp MPH, Vermeiren Y.   +10 more
europepmc   +1 more source

Metabonomics reveals that entomopathogenic nematodes mediate tryptophan metabolites that kill host insects. [PDF]

Front Microbiol, 2022
Zhang Y, Wang F, Zhao Z.
europepmc   +1 more source