Manipulating the molecular specificity of transcriptional biosensors for tryptophan metabolites and analogs. [PDF]
Xi C, Ma Y, Amrofell MB, Moon TS.
europepmc +1 more source
Altered Cerebrospinal Fluid Tryptophan–Kynurenine Pathway Metabolism in Multiple System Atrophy
Abstract Background Alterations in tryptophan–kynurenine (TRP‐KYN) metabolism, which is associated with neuroinflammation, remain unclear in multiple system atrophy (MSA). Objective The aim was to investigate cerebrospinal fluid (CSF) TRP metabolites in MSA and their associations with other biomarkers.
Ryunosuke Nagao +8 more
wiley +1 more source
Commensal-derived tryptophan metabolites fortify the skin barrier: Insights from a 50-species gnotobiotic model of human skin microbiome. [PDF]
Uberoi A +13 more
europepmc +1 more source
Abstract Background Plasma amino acid (AA) profiles in parenteral nutrition (PN)–dependent very preterm infants (VPIs) consistently show overprovision of essential AA (EAA) and arginine deficiency. This may have implications for growth and immune/inflammatory responses.
Frances Callaghan +6 more
wiley +1 more source
Gut microbiota-derived tryptophan metabolites improve total parenteral nutrition-associated infections by regulating Group 3 innate lymphoid cells. [PDF]
Huang L +12 more
europepmc +1 more source
The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie +5 more
wiley +1 more source
Biosynthetic Pathways of Tryptophan Metabolites in Saccharomyces cerevisiae Strain: Insights and Implications. [PDF]
Kung HC +4 more
europepmc +1 more source
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella +6 more
wiley +1 more source
Platelet Ido1 expression is induced during Plasmodium yoelii infection, altering plasma tryptophan metabolites. [PDF]
Blick-Nitko SK +8 more
europepmc +1 more source
Transport engineering as a strategy to realize rapeseed's potential as a protein‐rich food
The heavily pesticide‐dependent rapeseed is an under‐utilized protein source for food owing to anti‐nutritional glucosinolates. Transport engineering technology may reduce glucosinolates in seeds while increasing defense in vegetative parts. Abstract Rapeseed is the world's second‐largest oilseed crop, and the low‐value press cake that remains after ...
Jakob Skytte Thorsen +2 more
wiley +1 more source

