Results 171 to 180 of about 82,084 (287)

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

Food Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao, Jiayao Wang, Yilian Huang, Na Zhang, Xiaodan Shi, Zongcai Tu, Zuohua Xie, Tao Yuan, Hongmei Yin   +8 more
wiley   +1 more source

A CHROMATOGRAPHIC METHOD FOR THE DETECTION OF TRYPTOPHAN METABOLITES

Journal of Biological Chemistry, 1951
M, MASON, C P, BERG
openaire   +2 more sources

Secretory patterns of tryptophan metabolites in midgut carcinoid tumor cells

, 1997
Hormonal overproduction is a significant problem in patients with disseminated midgut carcinoid tumors. Serotonin (5-HT) is one major product secreted from such tumors and the urinary excretion of its metabolite (5-hydroxyindoleacetic acid, 5-HIAA ...
Nilsson, Ola,, Wängberg, Bo,, Westberg, G, Ahlman, Håkan,, Illerskog-Lindström, Ann-Christin,   +4 more
core  

Urolithin A, a Diet‐Derived Gut Microbial Metabolite Against Pulmonary Hypertension Identified via Molecular Docking, Molecular Dynamics and Surface Plasmon Resonance

Food Safety and Health, EarlyView.
Urolithin A, a gut microbial metabolite, binds TNF to suppress proliferation, inflammation, and oxidative stress, offering a promising microbe‐derived therapeutic avenue for pulmonary hypertension. ABSTRACT Pulmonary hypertension (PH) is a complex and multifactorial disease that poses a significant clinical challenge.
Yujie Qu, Yinghua Huo, Yichen Wang, Yao Mu, Xue Yu, Leiyu Tian, Jian Guo, Xuezhi Yang, Yucai Chen   +8 more
wiley   +1 more source

Dynamics of tryptophan metabolites and microbial adaptations during corn by-product fermentation in the pig gut microbiome. [PDF]

J Anim Sci Biotechnol
Toyoshi E, Watanabe M, Namai F, Yamane K, Kashima T, Ikeda-Ohtsubo W, Agista AZ, Yoshida A, Sakuma T, Fukuda I, Suzuki K, Yoshioka G, Imai Y, Tsuchida S, Nishiyama E, Shinkai H, Muneta Y, Uenishi H, Tobe R, Shirakawa H, Maekawa M, Mano N, Kitazawa H, Nishiyama K.   +23 more
europepmc   +1 more source

Tryptophan metabolites.

Indian pediatrics, 1981
A M, Sur, A, Bhatti
openaire   +1 more source

Monitoring and Mitigation Strategies for Hazardous Compounds in Chinese Rice Wine (Huangjiu): A Comprehensive Review

Food Safety and Health, EarlyView.
This review elucidates the formation pathways and detection technologies for ethyl carbamate, biogenic amines, and higher alcohols in Huangjiu. It concludes that integrated control frameworks are essential to decouple safety risks from the metabolic processes responsible for flavor development.
Lulu Liu, Zhiqiang Kong, Lin Li, Yifan Zhang, Bei Fan, Minmin Li   +5 more
wiley   +1 more source

Tongxie Yaofang ameliorates IBS-D by targeting the gut microbiota-derived tryptophan metabolites and AhR signaling axis. [PDF]

Front Microbiol
Xie X, Yan W, Gan C, Xiong W, Huang Y, Lin L, Lei X, Ke W, Chai Y, Tang H, Zhu H.   +10 more
europepmc   +1 more source

Second‐trimester multimetabolite panel for early preeclampsia rule‐out

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective We aimed to establish a high‐sensitivity, multimetabolite rule‐out model for the development of preeclampsia (PE), prioritizing minimizing false negatives to exclude low‐risk individuals from intensive surveillance confidently. Methods In this prospective, nested case–control study, maternal serum samples were collected between 20+0 ...
Matthews Silva Martins, Julyane N. S. Kaihara, Diego Fortes Salgueiro, Viviane Cunha Cardoso, Silvana Maria Quintana, Ricardo Carvalho Cavalli, Valerio Garrone Barauna, Valeria Cristina Sandrim   +7 more
wiley   +1 more source

Potential Impact of Microbial Dysbiosis and Tryptophan Metabolites in Advanced Stages of Colorectal Cancer. [PDF]

Biomedicines
Hulin A, Rifflet A, Castelli F, Giai Gianetto Q, Fenaille F, Aissat A, Matondo M, Fellahi S, Tournigand C, Junot C, Sansonetti P, Gomperts-Boneca I, Mestivier D, Sobhani I.   +13 more
europepmc   +1 more source