Results 61 to 70 of about 7,892 (182)
, 1996 Fluorescence titrations have shown that the voltage-sensitive probe RH421 interacts with the water-soluble protein ribulose-1,5-bisphosphate carboxylase/oxygenase and with Na+,K+-ATPase membrane fragments.
Zouni, Athina +4 more
core +2 more sources
Isolation and characterization of the rat tryptophan oxygenase gene. [PDF]
The EMBO Journal, 1982 Tryptophan oxygenase (TO, EC 1.13.1.12) from rat liver is subject to glucocorticoid and developmental control. To study the mechanism of regulation, TO mRNA sequences and the chromosomal TO gene were cloned. From a cDNA library prepared from rat liver poly(A)+ RNA enriched for TO mRNA, a recombinant plasmid containing TO cDNA sequences was identified ...
W, Schmid +7 more
openaire +2 more sources
A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile. [PDF]
Nitriles are uncommon in nature and are typically constructed from oximes through the oxidative decarboxylation of amino acid substrates or from the derivatization of carboxylic acids.
Lubeck, Wilson +10 more
core +1 more source
Journal of Biological Chemistry, 1967 1. The substrate, tryptophan, forms spectrophotometrically detectable enzyme-substrate complexes with tryptophan oxygenase (EC 1.13.1.12)—commonly known as tryptophan pyrrolase—when the iron atom of the heme prosthetic group is either divalent, trivalent, or combined with carbon monoxide. 2.
H, Maeno, P, Feigelson
openaire +2 more sources
PFAS properties and destruction methods: A focus on enzymatic degradation
Journal of Chemical Technology &Biotechnology, Volume 101, Issue 6, Page 1126-1152, June 2026.Abstract Per‐ and polyfluoroalkyl substances (PFAS) are known as ‘forever’ chemicals and have lasting detrimental impact on the environment and living organisms. To understand PFAS molecules better, this review begins with an overview of PFAS definition, classifications and applications, and then provides a comprehensive summary and critical analysis ...
Guobin Liang, Hua Zhao
wiley +1 more source
Inhibition of tryptophan metabolism by oestrogens in the rat: a factor in the aetiology of pellagra [PDF]
, 1984 The effect of the administration of oestrone sulphate on tryptophan metabolism has been assessed in rats in order to determine whether and to what extent inhibition of tryptophan metabolism by oestrogens may be a factor in the aetiology of pellagra, and ...
Bender, DA, Totoe, L
core
, 2005 The characteristics of glucocorticoid receptors, their sensitivity to glucocorticoid as well as the basal and glucocorticoid induced thyrosine aminotranferase (TAT) and tryptophan oxygenase (TO) activities were studied in rat liver during aging.
Vulović, Mojca D. +3 more
core +1 more source
Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
MedComm, Volume 7, Issue 6, June 2026.Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
PyrH and PrnB crystal structures
, 2006 Determination of the three-dimensional structure of enzymes at atomic resolution is a key prerequisite for elucidation of molecular mechanisms of catalysis and catalysis mechanism prediction.
De Laurentis, Walter
core
Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics
MedComm, Volume 7, Issue 6, June 2026.This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou +10 more
wiley +1 more source