Results 61 to 70 of about 5,899 (161)

Specific Inhibitory Action of Anisodamine against a Staphylococcal Superantigenic Toxin, Toxic Shock Syndrome Toxin 1 (TSST-1), Leading to Down-Regulation of Cytokine Production and Blocking of TSST-1 Toxicity in Mice [PDF]

Clinical and Vaccine Immunology, 2005
ABSTRACTToxic shock syndrome toxin 1 (TSST-1), produced byStaphylococcus aureus(including methicillin-resistantS. aureus), is a superantigenic toxin responsible for toxic shock syndrome as well as neonatal TSS-like exanthematous disease. TSST-1 exhibits its deleterious effects by leading to the abnormal proliferation of, e.g., Vβ2+T cells and ...
Saori, Nakagawa, Koji, Kushiya, Ikue, Taneike, Ken'ichi, Imanishi, Takehiko, Uchiyama, Tatsuo, Yamamoto   +5 more
openaire   +2 more sources

Does Cardiorespiratory Fitness Predict the Physiological and Psychological Stress Response to a Mathematics Exam in Secondary High School Students?

European Journal of Sport Science, Volume 26, Issue 5, May 2026.
ABSTRACT School is widely recognized as one of the primary sources of stress among adolescents. While some studies employing laboratory‐based stressors have suggested that adolescents with better cardiorespiratory fitness (CRF) may exhibit lower stress reactivity to psychosocial stressors, research based on real‐life stressors is lacking. Therefore, we
Markus Gerber, Michelle Haller, Vera Nina Looser, Sebastian Ludyga   +3 more
wiley   +1 more source

Staphylococcal Superantigen (TSST-1) Mutant Analysis Reveals that T Cell Activation Is Required for Biological Effects in the Rabbit Including the Cytokine Storm

Toxins, 2010
Staphylococcal superantigens (sAgs), such as toxic shock syndrome toxin 1 (TSST-1), induce massive cytokine production, which may result in toxic shock syndrome (TSS) and sepsis.
Norbert Stich, Martina Waclavicek, Nina Model, Martha M. Eibl   +3 more
doaj   +1 more source

Latitude Dictates Global Marine Diatom Dynamics: Insights From 25 years of Satellite Data

Earth's Future, Volume 14, Issue 5, May 2026.
Abstract Marine diatoms are key players in global biogeochemical cycles, yet their spatiotemporal dynamics and the underlying drivers remain poorly understood. Here, we developed a novel remote sensing model and utilized 25 years of global satellite data to investigate marine diatom biomass.
Deyong Sun, Minghui Li, Shengqiang Wang, Cédric Jamet, Davide Dionisi, Zixu Ye, Peng Chen   +6 more
wiley   +1 more source

The Secretome of Bullous Pemphigoid IgG‐Treated Keratinocytes Induces a Pro‐Inflammatory Eosinophil Response

Experimental Dermatology, Volume 35, Issue 5, May 2026.
ABSTRACT Bullous pemphigoid (BP) is an autoimmune blistering disease whereby the cutaneous antigens BP180 and BP230 are targeted by autoantibodies. Skin lesions in BP are characterized by an abundance of eosinophils. We recently demonstrated that the treatment of keratinocytes with antibodies from patients with BP induces a robust inflammatory response
Adrian P. Mansini, Lei Bao, Krishan D. Chhiba, Jing Li, Yulu Wang, Haley Gainer, M. Allen McAlexander, Christopher McCrae, Christopher D. Nazaroff, Fei Li Kuang, Kyle T. Amber   +10 more
wiley   +1 more source

018 TSST-1+ Staphylococcus aureus in bullous pemphigoid [PDF]

Journal of Investigative Dermatology, 2021
K.A. Messingham, M. Cahill, S. Kilgore, A. Munjal, P. Schlievert, J. Fairley   +5 more
openaire   +1 more source

Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling

Advanced Science, Volume 13, Issue 21, 13 April 2026.
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu, Zhi‐Bin Hu, Ling Hu, Yu‐Bing Wang, Qiong Zhang, Ning‐Ning Song, Xi‐Yue Liu, Jia‐Yin Chen, Hong‐Wen Zhu, Bing‐Yao Zhou, Yun‐Chao Tao, Li Zhao, Ze‐Xuan Li, Yi‐Wei Li, Jia‐Qi Chen, Si‐Xin Tu, Cong‐Cong Qi, Sai‐Dan Ding, Gang Peng, Lin Xu, Yu‐Qiang Ding   +20 more
wiley   +1 more source

Physiological Responses to Virtual Reality‐Based Stress Regulation and Relaxation Interventions: A Systematic Review

Stress and Health, Volume 42, Issue 2, April 2026.
ABSTRACT Physiological markers are increasingly used to monitor individuals undergoing Virtual Reality (VR) stress interventions. However, several challenges arise when employing these markers to assess the impact of VR stress interventions. This systematic review synthesises and critically discusses the literature on VR stress interventions across ...
Lisanne M. Robbemond, Matthijs L. Noordzij, Catheleine M. G. van Driel, Wim Veling   +3 more
wiley   +1 more source

The Prevalence of Toxin Shock Syndrome oxin ( TSST-1) Producing Clinical Isolates of Staphylococcus aureus StrainsIsolated from Shohada Hospital in Tabriz, Iran

Medical Laboratory Journal, 2011
Background and objectives: Staphylococcus aureus is one of the most important etiological agents of hospital and community acquired infections. The enterotoxins and toxin shock syndrome toxin (TSST-1) are among the most common virulent determinants of ...
Teyhoo M, Mobin H, Mozafari N A, Moadab S R, Sedigh Bayan KH, Mones Rast SH   +5 more
doaj  

Human Keratinocyte Response to Superantigens

mSphere, 2020
Staphylococcus aureus and Streptococcus pyogenes are significant human pathogens, causing infections at multiple body sites, including across the skin. Both are organisms that cause human diseases and secrete superantigens, including toxic shock syndrome
Patrick M. Schlievert, Francoise A. Gourronc, Donald Y. M. Leung, Aloysius J. Klingelhutz   +3 more
doaj   +1 more source