Results 1 to 10 of about 35,227 (304)

Toxin exposure and HLA alleles determine serum antibody binding to toxic shock syndrome toxin 1 (TSST-1) of Staphylococcus aureus [PDF]

Frontiers in Immunology, 2023
Life-threatening toxic shock syndrome is often caused by the superantigen toxic shock syndrome toxin-1 (TSST-1) produced by Staphylococcus aureus. A well-known risk factor is the lack of neutralizing antibodies.
Stefan Weiss, Stefan Weiss, Silva Holtfreter, Tanja C. Meyer, Frieder Schmiedeke, Clemens Cammann, Marcus Dörr, Marcus Dörr, Stephan B. Felix, Stephan B. Felix, Hans J. Grabe, Georg Homuth, Christian Kohler, Cedric Mahncke, Stephan Michalik, Matthias Nauck, Matthias Nauck, Nele Friedrich, Nele Friedrich, Stefanie Samietz, Henry Völzke, Henry Völzke, Uwe Völker, Uwe Völker, Barbara M. Bröker   +24 more
doaj   +4 more sources

The Association Between Onset of Staphylococcal Non-menstrual Toxic Shock Syndrome With Inducibility of Toxic Shock Syndrome Toxin-1 Production [PDF]

Frontiers in Microbiology, 2022
Non-menstrual toxic shock syndrome (non-mTSS) is a life-threatening disease caused by Staphylococcus aureus strains producing superantigens, such as staphylococcal enterotoxins A, B, C, and toxic shock syndrome toxin-1 (TSST-1).
Yusuke Taki, Yusuke Taki, Shinya Watanabe, Yusuke Sato’o, Xin-Ee Tan, Hisaya K. Ono, Kotaro Kiga, Yoshifumi Aiba, Teppei Sasahara, Aa Haeruman Azam, Kanate Thitiananpakorn, Srivani Veeranarayanan, Feng-Yu Li, Yuancheng Zhang, Tomofumi Kawaguchi, Sarah Hossain, Maniruzzaman, Dong-Liang Hu, Longzhu Cui   +18 more
doaj   +2 more sources

Toxic Shock Syndrome Toxin 1 Induces Immune Response via the Activation of NLRP3 Inflammasome [PDF]

Toxins, 2021
Staphylococcus aureus is a Gram-positive opportunistic pathogen which causes infections in a variety of vertebrates. Virulence factors are the main pathogenesis of S.
Lianci Peng, Jiali Jiang, Tingting Chen, Dongyi Xu, Fengqing Hou, Qingyuan Huang, Yuanyi Peng, Chao Ye, Dong-Liang Hu, Rendong Fang   +9 more
doaj   +2 more sources

Toxic Shock Syndrome Toxin-1 (TSST-1) in Staphylococcus aureus: Prevalence, Molecular Mechanisms, and Public Health Implications [PDF]

Toxins
Staphylococcus aureus is a significant pathogen responsible for various infections, with its production of toxic shock syndrome toxin-1 (TSST-1) being a central factor in the pathogenesis of toxic shock syndrome (TSS).
Rahima Touaitia, Nasir Adam Ibrahim, Eman Abdullah Almuqri, Nosiba S. Basher, Takfarinas Idres, Abdelaziz Touati   +5 more
doaj   +2 more sources

The Therapeutic Efficacy of MS473, a Fully Human Single-Chain Variable Fragment Targeting Staphylococcus aureus Toxic Shock Syndrome Toxin-1, in a D-Galactosamine-Sensitized Mouse Model of Lethal Shock [PDF]

BMC Microbiology
Toxic shock syndrome toxin-1 (TSST-1), produced by Staphylococcus aureus, is one of the most potent superantigens involved in causing life-threatening TSS and contributes to the onset of some autoimmune diseases.
Fatemeh Rahimi-Jamnani, Hamid Reza Moradi, Abolfazl Fateh, Masoumeh Azizi, Farzaneh Nazari, Mahdieh Soezi, Seyed Davar Siadat   +6 more
doaj   +2 more sources

Persistence survey of Toxic Shock Syndrome toxin-1 producing Staphylococcus aureus and serum antibodies to this superantigen in five groups of menstruating women [PDF]

BMC Infectious Diseases, 2010
Background Menstrual Toxic Shock Syndrome (mTSS) is thought to be associated with the vaginal colonization with specific strains of Staphylococcus aureus TSST-1 in women who lack sufficient antibody titers to this toxin.
Parsonnet Jeffrey, Hansmann Melanie A, Seymour Jon L, Delaney Mary L, DuBois Andrea M, Modern Paul A, Jones Michaelle B, Wild John E, Onderdonk Andrew B   +8 more
doaj   +5 more sources

Candida albicans promotes TSST-1 production by Staphylococcus aureus through glucose depletion and relief of CcpA-mediated repression [PDF]

Journal of Bacteriology
Menstrual toxic shock syndrome (mTSS) is a rare yet life-threatening disease that is caused when the opportunistic pathogenic bacterium Staphylococcus aureus releases the toxic shock syndrome toxin 1 (TSST-1) superantigen, which triggers systemic ...
Mathias Carriou, Cédric Badiou, Alexandre Soulard, Christophe d'Enfert, Karine Dufresne, Gérard Lina   +5 more
doaj   +2 more sources

Suppression of starvation-induced autophagy by recombinant toxic shock syndrome toxin-1 in epithelial cells. [PDF]

PLoS ONE, 2014
Toxic shock syndrome toxin-1 (TSST-1), a superantigen produced from Staphylococcus aureus, has been reported to bind directly to unknown receptor(s) and penetrate into non-immune cells but its function is unclear.
Krisana Asano, Yoshiya Asano, Hisaya K Ono, Akio Nakane   +3 more
doaj   +2 more sources

Toxic Shock Syndrome Toxin-1-Mediated Toxicity Inhibited by Neutralizing Antibodies Late in the Course of Continual in Vivo and in Vitro Exposure [PDF]

Toxins, 2014
Toxic shock syndrome (TSS) results from the host’s overwhelming inflammatory response and cytokine storm mainly due to superantigens (SAgs). There is no effective specific therapy.
Norbert Stich, Nina Model, Aysen Samstag, Corina S. Gruener, Hermann M. Wolf, Martha M. Eibl   +5 more
doaj   +2 more sources

Toxic shock syndrome associated with menstrual cup use

IDCases, 2021
Staphylococcal toxic shock syndrome is a rare but life-threatening condition. It occurs when Staphylococcus aureus bacteria colonizing the vagina of a healthy woman, produce toxic shock syndrome toxin 1 activating the immune system and leading to ...
Hind El Soufi, Yahya El Soufi, Sarah Al-Nuaimi, Farshad Bagheri   +3 more
doaj   +1 more source