Detection of toxic shock toxin (tst) gene in Staphylococcus aureus isolated from bovine milk samples [PDF]
Staphylococcus aureus is a major causative pathogen of clinical and subclinical mastitis in dairy cattle all over the world. This agent produces a variety of extracellular toxins and virulence factors in-cluding toxic shock syndrome toxin-1 (TSST-1 ...
S. Baniardalan +4 more
doaj +1 more source
Staphylococcal enterotoxin C has four subtypes that cause human diseases, designated SEC-1 to -4. This study shows that SEC-2 and SEC-3 are the most toxic subtypes in a rabbit model and are associated with human vaginal infections or colonization in ...
Olivia N. Chuang-Smith +1 more
doaj +1 more source
Enterococcus faecalis inhibits superantigen toxic shock syndrome toxin-1-induced interleukin-8 from human vaginal epithelial cells through tetramic acids. [PDF]
The vaginal mucosa can be colonized by many bacteria including commensal organisms and potential pathogens, such as Staphylococcus aureus. Some strains of S.
Amanda J Brosnahan +4 more
doaj +1 more source
Toxicity of staphylococcal toxic shock syndrome toxin 1 in rabbits [PDF]
Strains of Staphylococcus aureus associated with toxic shock syndrome produce toxic shock syndrome toxin 1 (TSST 1), which is lethal to conventional rabbits and acts synergistically with gram-negative lipopolysaccharide. The lethal effect of TSST 1 was examined in specific-pathogen-free rabbits on the basis that these rabbits, being less colonized by ...
J C, de Azavedo, J P, Arbuthnott
openaire +2 more sources
Background Staphylococcal superantigens are virulence factors that help the pathogen escape the immune system and develop an infection. Toxic shock syndrome toxin (TSST)-1 is one of the most studied superantigens whose role in toxic shock syndrome and ...
Mahdieh Soezi +12 more
doaj +1 more source
Objective To explore the therapeutic method of streptococcal toxin shock syndrome and necrotizing fasciitis caused by streptococcus pyogenes. Methods We retrospectively reviewed 2 cases of streptococcus pyogenes infection, summarize the treatment ...
Liu Xiaofeng +4 more
doaj +1 more source
Local Epidermal Growth Factor Receptor Signaling Mediates the Systemic Pathogenic Effects of Staphylococcus aureus Toxic Shock Syndrome. [PDF]
Secreted factors of Staphylococcus aureus can activate host signaling from the epidermal growth factor receptor (EGFR). The superantigen toxic shock syndrome toxin-1 (TSST-1) contributes to mucosal cytokine production through a disintegrin and ...
Laura M Breshears +4 more
doaj +1 more source
In Silico Evaluation of a Mutant Toxic Shock Syndrome Toxin-1 (TSST-1) of Staphylococcus aureus as a Putative Vaccine Candidate [PDF]
Introduction: The development of a vaccine against Staphylococcus aureus has proven to be much more difficult than expected. In this study, we considered and analyzed a mutant Toxic Shock Syndrome Toxin-1 (TSST-1) as a potential vaccine candidate ...
Mohsen Nazari, Farzad Badmasti
doaj +1 more source
Effect of toxic shock syndrome toxin 1 on chicken embryos [PDF]
Staphylococcus aureus strains associated with toxic shock syndrome produce toxic shock syndrome toxin 1 (TSST1). This toxin has a variety of biological effects, including enhanced lethality in rabbits in the presence of sublethal amounts of lipopolysaccharide (LPS).
J C, de Azavedo +2 more
openaire +2 more sources
Immunogenicity of toxins during Staphylococcus aureus infection [PDF]
AB - BACKGROUND: Toxins are important Staphylococcus aureus virulence factors, but little is known about their immunogenicity during infection. Here, additional insight is generated. METHODS: Serum samples from 206 S.
Antri, K. (Kenza) +15 more
core +9 more sources

