Results 81 to 90 of about 9,124 (209)

The Secretome of Bullous Pemphigoid IgG‐Treated Keratinocytes Induces a Pro‐Inflammatory Eosinophil Response

Experimental Dermatology, Volume 35, Issue 5, May 2026.
ABSTRACT Bullous pemphigoid (BP) is an autoimmune blistering disease whereby the cutaneous antigens BP180 and BP230 are targeted by autoantibodies. Skin lesions in BP are characterized by an abundance of eosinophils. We recently demonstrated that the treatment of keratinocytes with antibodies from patients with BP induces a robust inflammatory response
Adrian P. Mansini, Lei Bao, Krishan D. Chhiba, Jing Li, Yulu Wang, Haley Gainer, M. Allen McAlexander, Christopher McCrae, Christopher D. Nazaroff, Fei Li Kuang, Kyle T. Amber   +10 more
wiley   +1 more source

Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling

Advanced Science, Volume 13, Issue 21, 13 April 2026.
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu, Zhi‐Bin Hu, Ling Hu, Yu‐Bing Wang, Qiong Zhang, Ning‐Ning Song, Xi‐Yue Liu, Jia‐Yin Chen, Hong‐Wen Zhu, Bing‐Yao Zhou, Yun‐Chao Tao, Li Zhao, Ze‐Xuan Li, Yi‐Wei Li, Jia‐Qi Chen, Si‐Xin Tu, Cong‐Cong Qi, Sai‐Dan Ding, Gang Peng, Lin Xu, Yu‐Qiang Ding   +20 more
wiley   +1 more source

Physiological Responses to Virtual Reality‐Based Stress Regulation and Relaxation Interventions: A Systematic Review

Stress and Health, Volume 42, Issue 2, April 2026.
ABSTRACT Physiological markers are increasingly used to monitor individuals undergoing Virtual Reality (VR) stress interventions. However, several challenges arise when employing these markers to assess the impact of VR stress interventions. This systematic review synthesises and critically discusses the literature on VR stress interventions across ...
Lisanne M. Robbemond, Matthijs L. Noordzij, Catheleine M. G. van Driel, Wim Veling   +3 more
wiley   +1 more source

Interfacial Atomic and Electronic Structures of LSM/YSZ Thin Films as Models for SOC Air Electrodes

ChemElectroChem, Volume 13, Issue 6, 17 March 2026.
Lanthanum–strontium manganite/yttria‐stabilized zirconia thin films serve as model systems for solid oxide cell electrodes, where high‐resolution scanning transmission electron microscopy and X‐ray photoelectron spectroscopy reveal atomistic interfacial features and electronic structure supported by atomistic modeling of these interfaces.
Hebatallah Ali, Patricia König, Xuan Quy Tran, Anton Kaus, Hanna Türk, Adnan Hammud, Zahra Gheisari, Vaibhav Vibhu, Vladimir Roddatis, Franz‐Philipp Schmidt, Raoul Blume, Patrick Zeller, Till Frömling, Felix Gunkel, Axel Knop‐Gericke, Karsten Reuter, Rüdiger‐A. Eichel, Christoph Scheurer, Thomas Lunkenbein   +18 more
wiley   +1 more source

Specific Inhibitory Action of Anisodamine against a Staphylococcal Superantigenic Toxin, Toxic Shock Syndrome Toxin 1 (TSST-1), Leading to Down-Regulation of Cytokine Production and Blocking of TSST-1 Toxicity in Mice [PDF]

Clinical and Vaccine Immunology, 2005
ABSTRACTToxic shock syndrome toxin 1 (TSST-1), produced byStaphylococcus aureus(including methicillin-resistantS. aureus), is a superantigenic toxin responsible for toxic shock syndrome as well as neonatal TSS-like exanthematous disease. TSST-1 exhibits its deleterious effects by leading to the abnormal proliferation of, e.g., Vβ2+T cells and ...
Saori, Nakagawa, Koji, Kushiya, Ikue, Taneike, Ken'ichi, Imanishi, Takehiko, Uchiyama, Tatsuo, Yamamoto   +5 more
openaire   +2 more sources

See, Touch, Feel, and Express: Achieving Safe and Natural Outcomes With HA Fillers—An International Consensus

Journal of Cosmetic Dermatology, Volume 25, Issue 3, March 2026.
ABSTRACT Background The concept of “natural outcomes” in filler treatments has been explored in clinical studies and literature, yet remains loosely defined, subjective, and lacks standardized assessment criteria. Aims To propose a multidimensional Natural Outcomes Framework to systematically define, assess, and communicate natural outcomes following ...
Atchima Suwanchinda, Hosung Choi, Niamh Corduff, Haiyan Cui, Lindsay Gail Torralba Garcia, Martina Kerscher, Ting Song Lim, Olivia Ong, Je‐Young Park, Danai Praditsuwan, Tuck Wah Siew, Fang‐Wen Tseng, Raymond Wu, Tatjana Pavicic   +13 more
wiley   +1 more source

Modeling Anti-HIV-1 HSPC-Based Gene Therapy in Humanized Mice Previously Infected with HIV-1. [PDF]

, 2018
Investigations of anti-HIV-1 human hematopoietic stem/progenitor cell (HSPC)-based gene therapy have been performed by HIV-1 challenge after the engraftment of gene-modified HSPCs in humanized mouse models.
An, Dong Sung, Arokium, Hubert, Chen, Irvin SY, Cortado, Ruth, Jung, Yujin, Kamata, Masakazu, Khamaikawin, Wannisa, Kim, Patrick, Kim, Sanggu, Lam, Jennifer, Presson, Angela P, Shimizu, Saki, Wen, Jing, Xie, Yiming   +13 more
core   +2 more sources

Staphylococcal Superantigen (TSST-1) Mutant Analysis Reveals that T Cell Activation Is Required for Biological Effects in the Rabbit Including the Cytokine Storm

Toxins, 2010
Staphylococcal superantigens (sAgs), such as toxic shock syndrome toxin 1 (TSST-1), induce massive cytokine production, which may result in toxic shock syndrome (TSS) and sepsis.
Norbert Stich, Martina Waclavicek, Nina Model, Martha M. Eibl   +3 more
doaj   +1 more source

Population and Virulence Factor Analysis of Staphylococcus aureus from Bovine Mastitis. [PDF]

, 2000
End of Project ReportsStaphylococcus aureus is a major cause of bovine mastitis and the disease is responsible for substantial economic losses in the dairy industry world-wide.
Fitzgerald, J.R., Hartigan, Patrick J., Meaney, William J, Smyth, Cyril James   +3 more
core  

Acute Stress Impacts Executive‐Social Function: Evidence From Prefrontal Activation and fNIRS‐Based Hyperscanning

Brain and Behavior, Volume 16, Issue 1, January 2026.
Trends in increased PFC activation and increased IBS may be indicative of compensatory neural mechanisms preserving performance under stress. Cognitive flexibility correlated with cooperative outcomes, tentatively supporting a neurobehavioral executive‐social link during acute stress inviting more research.
Zhihua Guo, Yue Gong, Liu Yang, Yushan Li, Rui Qiu, Xia Zhu   +5 more
wiley   +1 more source