Results 91 to 100 of about 59,427 (290)

Quantitative Systems Pharmacology Modeling of Platelet Responses to Recombinant ADAMTS13 in Patients With Congenital Thrombotic Thrombocytopenic Purpura

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra‐rare, life‐threatening thrombotic microangiopathy caused by a severe inherited deficiency of ADAMTS13, a von Willebrand factor (VWF) cleaving enzyme. Inadequate clinical endpoint data often make it challenging to statistically power clinical trials in ultra‐rare diseases ...
Cameron McBride, Jiaolong Jiang, Zhiwei Zhang, John Tolsma, Parth Patwari, Björn Mellgård, Majid Vakilynejad, Indranil Bhattacharya, Andy Z. X. Zhu   +8 more
wiley   +1 more source

Functional Electrolyte Additives: A Pinch of Salt/Solvent to an Electrolyte for High Energy Density Lithium‐Ion and Lithium–Metal Batteries

Small, EarlyView.
Electrolytes, often termed as the “blood” of battery play a decisive role in determining their performance metrics. This review thoroughly analyzes the role of functional electrolyte additives improving the performance and safety of Li‐ion/Li–metal batteries involving film formation, overcharge control, wide temperature and voltage operation ...
Chenrayan Senthil, Amutha Subramani, Ram K. Gupta, Zdeněk Sofer   +3 more
wiley   +1 more source

Prognostic value of contrast‐enhanced ultrasound in dogs with acute renal injury treated with haemodialysis

Veterinary Record, Volume 196, Issue 6, 15/22 March 2025.
Abstract Background It is clinically relevant to predict outcomes in dogs with acute kidney injury (AKI) treated with haemodialysis. The aim of this study was to evaluate the prognostic value of contrast‐enhanced ultrasound (CEUS) and its role in discriminating between AKI and acute impairment associated with chronic kidney disease (AKI/CKD).
Caterina Puccinelli, Ilaria Lippi, Tina Pelligra, Simonetta Citi   +3 more
wiley   +1 more source

Hydroxychloroquine, TTP, COVID-19, and SLE

Turkish Journal of Hematology, 2021
Pathum Sookaromdee, Viroj Wiwanitkit
doaj   +1 more source

Re-thinking the role of intellectual property in nano-strategy

Nanotechnology Reviews, 2012
In two past studies we observed and analyzed a group of European new and adolescent ventures, looking in particular at how they were about exploiting nanotechnology-based business opportunities, what was the role of intellectual property rights (IPRs ...
Giordani Sara
doaj   +1 more source

Season of birth and variations in male reproductive health: A population‐based cohort study

Andrology, EarlyView.
Abstract Background Season of birth has been associated with various later reproductive health outcomes in women, but little is known on the potential associations in men. Objectives To investigate the association between season of birth and semen characteristics, testes volume and reproductive hormone levels in young men.
Anne Gaml‐Sørensen, Nis Brix, Sandra Søgaard Tøttenborg, Karin Sørig Hougaard, Siri Eldevik Håberg, Mikko Myrskylä, Gunnar Toft, Jens Peter Ellekilde Bonde, Cecilia Høst Ramlau‐Hansen   +8 more
wiley   +1 more source

Rituximab for TTP [PDF]

American Journal of Hematology, 2005
Sarah M. Scott, Zbigniew M. Szczepiorkowski   +1 more
openaire   +3 more sources

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Role of plasma exchange in a post-partum case of severe thrombotic thrombocytopenic purpura with acute kidney injury

Journal of Family Medicine and Primary Care
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disease present with the classic pentad of microangiopathic hemolytic anemia (MAHA), fever, neurologic changes, thrombocytopenia, and renal dysfunction.
Jyoti Bharti, Tulika Chandra, Archana Solanki, Ashutosh Singh, D. Himanshu Reddy, Mallika Agarwal   +5 more
doaj   +1 more source

Partial starch substitution with resistant starch lowers postprandial glucose and glycaemic variability in people with type 2 diabetes

Diabetic Medicine, EarlyView.
Abstract Aims Approximately 40% of the caloric intake of the UK diet consists of starch. Most of which is readily digestible, thereby raising blood glucose. However, resistant starch (RS) evades metabolism in the small intestine, and in healthy adults, partial substitution of the diet with RS lowers postprandial glycaemia.
Sineaid M. Collins, M. Bernadette Egan, Martin B. Whyte, M. Denise Robertson   +3 more
wiley   +1 more source