Results 51 to 60 of about 59,427 (290)

A closer look at isodoublet vector leptoquark solution to the R D ∗ $$ {R}_{D^{\left(\ast \right)}} $$ anomaly

Journal of High Energy Physics, 2023
We discuss a model with a SU(2) L doublet vector leptoquark (LQ), motivated by the recent experimental results relating to the lepton universality of B ¯ $$ \overline{B} $$ → D (*) τ ν ¯ τ $$ \tau {\overline{\nu}}_{\tau } $$ .
Syuhei Iguro, Yuji Omura
doaj   +1 more source

Plasma exchange in thrombotic microangiopathies (TMAs) other than thrombotic thrombocytopenic purpura (TTP).

Hematology. American Society of Hematology. Education Program, 2017
Thrombotic microangiopathies (TMAs) are a diverse group of disorders that are characterized by common clinical and laboratory features. The most commonly thought-of TMA is thrombotic thrombocytopenic purpura (TTP).
J. Winters
semanticscholar   +1 more source

A Complementarity‐Based Approach to De Novo Binder Design

Advanced Science, EarlyView.
A novel method for surface complementarity detection (HECTOR) enables highly efficient docking and design of protein interfaces. Applied to therapeutically relevant targets, this method yields de novo binders with potent antagonistic activity. As a first‐principles approach, HECTOR offers a training‐free solution to the binder design problem and is ...
Kateryna Maksymenko, Valeriia Hatskovska, Murray Coles, Narges Aghaallaei, Natalia Pashkovskaia, Natalia Borbarán‐Bravo, Matteo Pilz, Philip Bucher, Mareike Volz, Joana Pereira, Marcus D. Hartmann, Ghazaleh Tabatabai, Judith Feucht, Stefan Liebau, Patrick Müller, Andrei N. Lupas, Julia Skokowa, Mohammad ElGamacy   +17 more
wiley   +1 more source

Assessment and Monitoring of Patients with Immune-Mediated Thrombotic Thrombocytopenic Purpura (iTTP): Strategies to Improve Outcomes

Journal of Blood Medicine, 2020
Selin Kucukyurt, Ahmet Emre Eskazan Division of Hematology, Department of Internal Medicine, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, TurkeyCorrespondence: Ahmet Emre EskazanIstanbul University-Cerrahpasa, Cerrahpasa ...
Kucukyurt S, Eskazan AE
doaj  

A Rare Association of Thrombotic Thrombocytopenic Purpura with Systemic Lupus Erythematosus in a Sudanese Woman: Case Report

Journal of Blood Medicine, 2021
Amel Awad Ibn Idris Rodwan,1 Osama Khder Ahmed Elmansour,1,2 Amar F Eldow Ahmed,3 Elnour Mohammed Elagib,1,4 Noha Ibrahim Ahmed Eltahir,4,5 Abubaker Hassan,6 Sara M El-Sadig,7 Abdel Gaffar Abdel Allah Mohammed,8 Huyam H Awadalla,9 Abubakr Abdalwahab ...
Ibn Idris Rodwan AA, Ahmed Elmansour OK, Ahmed AFE, Elagib EM, Ahmed Eltahir NI, Hassan A, El-Sadig SM, Mohammed AGAA, Awadalla HH, Mohammed AA, Adam Essa ME   +10 more
doaj  

Human neutrophil peptides inhibit cleavage of von Willebrand factor by ADAMTS13: a potential link of inflammation to TTP.

Blood, 2016
Infection or inflammation may precede and trigger formation of microvascular thrombosis in patients with acquired thrombotic thrombocytopenic purpura (TTP). However, the mechanism underlying this clinical observation is not fully understood.
Vikram G. Pillai, J. Bao, C. Zander, Jenny K. McDaniel, P. S. Chetty, S. Seeholzer, K. Bdeir, D. Cines, X. Zheng   +8 more
semanticscholar   +1 more source

HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation

eLife, 2023
Tristetraprolin (TTP) is a critical negative immune regulator. It binds AU-rich elements in the untranslated-regions of many mRNAs encoding pro-inflammatory mediators, thereby accelerating their decay.
Sara Scinicariello, Adrian Soderholm, Markus Schäfer, Alexandra Shulkina, Irene Schwartz, Kathrin Hacker, Rebeca Gogova, Robert Kalis, Kimon Froussios, Valentina Budroni, Annika Bestehorn, Tim Clausen, Pavel Kovarik, Johannes Zuber, Gijs A Versteeg   +14 more
doaj   +1 more source

Color‐Filter‐Free Image Sensor Using CsPbBr3 Quantum‐Dot‐Based Tamm Plasmon Photodetector for Photonic Synapse Facial Recognition

Advanced Science, EarlyView.
A cutting‐edge color‐filter‐free photodetector that seamlessly integrates a monolayer perovskite quantum dots absorber by leveraging Tamm plasmon resonance enhances optical absorption through strong light–matter coupling and demonstrates synaptic‐like dynamics, enabling neuron‐inspired facial recognition.
Meng‐Cheng Yen, Yung‐Chi Yao, Chia‐Jung Lee, Shi‐Hui Huang, Wei Jie Hong, Yuto Kajino, Hsu‐Cheng Hsu, Min‐Hsiung Shih, Gong‐Ru Lin, Kaoru Tamada, Jinn‐Kong Sheu, Ya‐Ju Lee   +11 more
wiley   +1 more source

Cobalamin Deficient Thrombotic Microangiopathy: a case of TTP or Pseudo-TTP

West Virginia Medical Journal, 2018
A thrombotic microangiopathy (TMA) occurs when a patient presents with microangiopathic hemolytic anemia, thrombocytopenia and organ damage. There are many causes of TMAs, but thrombotic thrombocytopenic purpura (TTP) must always be considered because of its high mortality rate.
Adrienne Mays, Anne Jarrell, Tammy Bannister, Adam M. Franks   +3 more
openaire   +2 more sources

Aryl hydrocarbon receptor inhibits inflammation in DSS-induced colitis via the MK2/p-MK2/TTP pathway

International Journal of Molecular Medicine, 2017
The pathogenesis of inflammatory bowel disease (IBD) is believed to be associated with the abnormal expression of inflammatory factors. The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor, which can suppress the inflammatory ...
Qimeng Wang, Kunqiu Yang, Bin-ze Han, B. Sheng, Jiuheng Yin, Aimin Pu, Liangzi Li, Lihua Sun, Min Yu, Y. Qiu, W. Xiao, Hua Yang   +11 more
semanticscholar   +1 more source