Results 41 to 50 of about 96,150 (234)

Pioneers in the Victorian provinces: veterinarians, public health and the urban animal economy [PDF]

, 2002
From the 1850s in Britain, concerns were growing about the role of animals in transmitting disease to man, whether through the food chain or through infection.
Hardy, A
core   +1 more source

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

Bovine tuberculosis: a retrospective study at Jos abattoir, Plateau State, Nigeria

The Pan African Medical Journal, 2016
INTRODUCTION: Nigeria has the thirteenth highest burden of human tuberculosis. The current increasing incidence of tuberculosis in humans, particularly in immune-compromised persons, has given interest in the zoonotic importance of Mycobacterium bovis in
Lilian Akudo Okeke, Olufunmilayo Fawole, Maryam Muhammad, Ikenna Osemeka Okeke, Patrick Nguku, Peter Wasswa, David Dairo, Simeon Cadmus   +7 more
doaj   +1 more source

Risk Factors for Zoonotic Tuberculosis at the Wildlife–Livestock–Human Interface in South Africa

Pathogens, 2019
A cross-sectional study was conducted to investigate the risk factors associated with zoonotic tuberculosis in humans and its transmission to people living at the wildlife−livestock−human interface. A questionnaire was administered to collect
Petronillah R. Sichewo, Anita L. Michel, Jolly Musoke, Eric M.C. Etter   +3 more
doaj   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

KCNJ2 is Required for NLRP3 Inflammasome Activation That Drives Allergic Airway Inflammation and Remodeling

Advanced Science, EarlyView.
This study aims to evaluate the impact of the potassium channel KCNJ2 on asthma development. KCNJ2 promotes NLRP3 inflammasome activation through both Ca2+ influx and K+ efflux in airway epithelial cells, which drives allergic airway inflammation and remodeling, suggesting a promising therapeutic target for asthma.
Yachao Cui, Shumei Wu, Yang Peng, Yiqi Liu, Li Che, Shiying Chen, Feng Zhang, Dajiang Qin, Shiyue Li, Pixin Ran, Wenguang Yin   +10 more
wiley   +1 more source

Effect of Mycobacterium bovis infection in cattle on changes in appetite-related hormones

Austral Journal of Veterinary Sciences, 2018
There are limited studies available for appetite-related hormonal changes in bovine tuberculosis, therefore the purpose of this study was to determine the changes in appetite-related hormones (leptin, ghrelin, and nesfatin -1) of cattle with tuberculosis
Sinasi Askar, Tunay Kontas Askar, Murat Guzel   +2 more
doaj   +1 more source

Contribution du Cirad-Emvt à l'appui scientifique du projet FSP "concertation agricole et structuration des filières en Ouganda" : rapport de mission en Ouganda du 15 au 22 mars 2003 [PDF]

, 2003
Présent en Ouganda depuis 1998, le Programme Productions Animales (CIRAD-EMVT) n'avait pour l'instant oeuvré qu'au travers de missions courtes et d'appui à des stagiaires et un CSN. Le démarrage du FSP "concertation agricole et soutien aux filières (CASF)
Faye, Bernard, Grimaud, Patrice
core  

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Inside Mycobacterium bovis SB0120 spoligotype circulating in Italy: analysis of the most frequent genotypes by whole genome sequencing

Frontiers in Microbiology
Bovine tuberculosis (bTB) is a chronic inflammatory disease primarily caused by Mycobacterium bovis. The infection affects domestic animals and wildlife, posing a zoonotic risk to humans.
Erika Scaltriti, Karaman Iyad, Maria Beatrice Boniotti, Ilaria Menozzi, Luca Bolzoni, Dorotea Ippolito, Flavia Pruiti Ciarello, Daniela Loda, Mario D’Incau, Mariagrazia Zanoni, Vincenzo Di Marco Lo Presti, Piera Mazzone, Stefano Gavaudan, Maria Lodovica Pacciarini   +13 more
doaj   +1 more source