Results 61 to 70 of about 578,223 (240)

Effects of Heredity in Bovine Tuberculosis [PDF]

The Veterinary Journal (1900), 1914
n ...
openaire   +2 more sources

Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation

Advanced Science, EarlyView.
Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie, Ziye Huang, Zhiyuan Zhang, Yiqiang Zhu, Xiaoqing Liu, Lei Wang, Tongyu Bi, Taizhen Liang, Jintao Lai, Meilin Hu, Guochang Qiu, Shiqi Xiao, Sen Liu, Yaoming Liu, Haiyue Rao, Tao Chen, Haojie Peng, Bin Zhang, Jia Tang, Qianying Li, Yaxin Li, Yuxin Hou, Weibo Yang, Hewei Jiang, Xiancai Ma   +24 more
wiley   +1 more source

Bovine tuberculosis: a retrospective study at Jos abattoir, Plateau State, Nigeria

The Pan African Medical Journal, 2016
INTRODUCTION: Nigeria has the thirteenth highest burden of human tuberculosis. The current increasing incidence of tuberculosis in humans, particularly in immune-compromised persons, has given interest in the zoonotic importance of Mycobacterium bovis in
Lilian Akudo Okeke, Olufunmilayo Fawole, Maryam Muhammad, Ikenna Osemeka Okeke, Patrick Nguku, Peter Wasswa, David Dairo, Simeon Cadmus   +7 more
doaj   +1 more source

Risk Factors for Zoonotic Tuberculosis at the Wildlife–Livestock–Human Interface in South Africa

Pathogens, 2019
A cross-sectional study was conducted to investigate the risk factors associated with zoonotic tuberculosis in humans and its transmission to people living at the wildlife−livestock−human interface. A questionnaire was administered to collect
Petronillah R. Sichewo, Anita L. Michel, Jolly Musoke, Eric M.C. Etter   +3 more
doaj   +1 more source

Molecular Characterisation of Mycobacterium bovis Isolates from Cattle Slaughtered in Adamawa and Gombe States, North-Eastern Nigeria

Current Issues in Molecular Biology, 2023
Bovine tuberculosis is endemic in Nigeria with control measures as provided by the laws of the country being minimally enforced mostly at the abattoirs only. This study focused on bovine tuberculosis in Adamawa and Gombe States. Tuberculosis lesions were
Sadiq Mohammed Damina, David Atomanyi Barnes, Bitrus Inuwa, Gulak Hussaini Ularamu, Mohammed Bello, Olu Solomon Okaiyeto, Ayuba Caleb Kudi, Jeewan Thapa, Chie Nakajima, Yasuhiko Suzuki   +9 more
doaj   +1 more source

scH16S‐Seq Maps Klebsiella pneumoniae‐Associated Myeloid States and Reveals a CD38–NAD Immunometabolic Axis That Impairs Lysosomal Acidification in Sepsis

Advanced Science, EarlyView.
Single‐cell host–bacterial 16S co‐sequencing (scH16S‐seq) integrates cell‐associated bacterial 16S‐derived signals with host transcriptomes to resolve bacterial signal‐enriched myeloid states in Klebsiella pneumoniae sepsis. Complementary pharmacological and genetic analyses define a CD38–NAD immunometabolic axis connecting mitochondrial bioenergetic ...
Yangguang Li, Yilong Yu, Fang Qin, Shenxing Li, Xuanheng Li, Peizhao Liu, Juanhan Liu, Haiqing Liu, Songqi Jing, Jianghao Zou, Sicheng Li, Jiayang Li, Tao Zheng, Yun Zhao, Jianan Ren, Xiuwen Wu   +15 more
wiley   +1 more source

Spatially Confined/Ligand‐Directed Ultrabright NIR‐AIE Nanoprobe for In Vitro Rapid Detection and In Situ Imaging of Bacterial Septic Arthritis

Advanced Science, EarlyView.
Inorganic PbS quantum dots spatially confine AIEgens and enable cooperative luminescence within a ligand‐directed core–shell–shell nanoassembly, generating ultrabright NIR PPANPs with enhanced fluorescence and photothermal performance. The platform enables 10‐min S.
Yujian Li, Jia Shu, Sijia Lv, Leilei Qin, Xuefeng Luo, PengCheng Xiao, Huan Cai, Xin Gao, Yan Zhao, Haotian Zhou, Yaji Yang, Zhenglin Zhu, Shijia Ding, Juan Li, Rui Chen, Wei Huang   +15 more
wiley   +1 more source

Global Gene Expression and Systems Biology Analysis of Bovine Monocyte-Derived Macrophages in Response to In Vitro Challenge with Mycobacterium bovis [PDF]

, 2012
peer-reviewedBackground Mycobacterium bovis, the causative agent of bovine tuberculosis, is a major cause of mortality in global cattle populations. Macrophages are among the first cell types to encounter M.
Karsten Hokamp (42210), Magee, David A, Conlon, Kevin M., Park Stephen D. E., Gordon, Stephen V, Karsten Hokamp, David J. Lynn (107188), Conlon Kevin M., Lynn, David J, Taraktsoglou, Maria, Nicolas C Nalpas, Stephen D. E. Park (183071), Stephen V Gordon, Stephen V. Gordon (108974), MacHugh David E., Gordon Stephen V., Eamonn Gormley (84870), Nalpas Nicolas C., Nicolas C. Nalpas (183064), David A. Magee (183048), Killick, Kate E, John A Browne, MacHugh, David E, Nalpas, Nicolas C., Kate E Killick, David E MacHugh, Gormley, Eamonn, Lynn David J., David E. MacHugh (183089), Park, Stephen D. E., Hokamp, Karsten, David J Lynn, Maria Taraktsoglou (183055), Browne John A., Killick Kate E., Kevin M Conlon, Kevin M. Conlon (183076), Eamonn Gormley, Gormley Eamonn, David A Magee, Taraktsoglou Maria, Kate E. Killick (183061), Hokamp Karsten, Magee David A., Browne, John A, Stephen D E Park, Maria Taraktsoglou, John A. Browne (183068)   +47 more
core   +2 more sources

Inside Mycobacterium bovis SB0120 spoligotype circulating in Italy: analysis of the most frequent genotypes by whole genome sequencing

Frontiers in Microbiology
Bovine tuberculosis (bTB) is a chronic inflammatory disease primarily caused by Mycobacterium bovis. The infection affects domestic animals and wildlife, posing a zoonotic risk to humans.
Erika Scaltriti, Karaman Iyad, Maria Beatrice Boniotti, Ilaria Menozzi, Luca Bolzoni, Dorotea Ippolito, Flavia Pruiti Ciarello, Daniela Loda, Mario D’Incau, Mariagrazia Zanoni, Vincenzo Di Marco Lo Presti, Piera Mazzone, Stefano Gavaudan, Maria Lodovica Pacciarini   +13 more
doaj   +1 more source

Effect of Mycobacterium bovis infection in cattle on changes in appetite-related hormones

Austral Journal of Veterinary Sciences, 2018
There are limited studies available for appetite-related hormonal changes in bovine tuberculosis, therefore the purpose of this study was to determine the changes in appetite-related hormones (leptin, ghrelin, and nesfatin -1) of cattle with tuberculosis
Sinasi Askar, Tunay Kontas Askar, Murat Guzel   +2 more
doaj   +1 more source