Results 31 to 40 of about 8,203 (163)

Pathways to Progressive Disability in Multiple Sclerosis: The Role of Glial Cells in Chronic CNS Inflammation

Glia, EarlyView.
ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive neurodegeneration and focal demyelinated lesions. Traditionally considered an autoimmune disease, MS is driven by the immune system's attack on CNS myelin, resulting in cumulative disability.
Volker Siffrin
wiley   +1 more source

Incidence of tuberculous meningitis in the State of Santa Catarina, Brazil

Revista da Sociedade Brasileira de Medicina Tropical, 2014
Introduction The aim of this study was to estimate the incidence of tuberculous meningitis in the State of Santa Catarina (SC), Brazil, during the period from 2001 to 2010.
Cíntia Helena de Souza, Ayaka Yamane, Jeison Cleiton Pandini, Luciane Bisognin Ceretta, Fabiane Ferraz, Glauco Duarte da Luz, Priscyla Waleska Simões   +6 more
doaj   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source

A Rare Presentation of Invasive Tuberculosis of the Central Nervous System in an Immunocompetent Patient in a Nonendemic Country

Case Reports in Neurological Medicine, 2018
We herein report a rare case of a 25-year-old immunocompetent male patient with disseminated tuberculosis of central nervous system (CNS), first presenting as multiple cerebral lesions with no meningeal involvement. Subsequent diagnostic workup disclosed
Rita Martins, Carlos Casimiro, Ana Valverde, Jose Campillo   +3 more
doaj   +1 more source

Differences of the 6N and 6J Substrains of C57BL/6 Mice in the Development of Experimental Autoimmune Encephalomyelitis

MedComm, Volume 6, Issue 7, July 2025.
The 6J substrain exhibits more severe EAE than 6N, with increased macrophages, CD8+, and B cells in the CNS, as well as a higher proinflammatory profile and lower anti‐inflammatory profile, correlating with differences in microbial taxa. ABSTRACT Multiple sclerosis (MS) is an autoimmune disease causing neuroinflammation and demyelination in the central
Ana Isabel Álvarez‐López, Eduardo Ponce‐España, Ivan Cruz‐Chamorro, Guillermo Santos‐Sánchez, Ignacio Bejarano, Nuria Álvarez‐Sánchez, Patricia Judith Lardone, Antonio Carrillo‐Vico   +7 more
wiley   +1 more source

Acute Stroke in Tubercular Meningitis: A Case Report

Journal of Nepal Medical Association, 2019
Most of the strokes in tubercular meningitis are multiple, bilateral, and located in the basal ganglia, especially the ‘tubercular zone’, which comprises of the caudate, anterior thalamus, anterior limb, and genu of the internal capsule.
Suzit Bhusal, Sujata Dahal, Neha Gautam, Prakash Banjade   +3 more
doaj   +1 more source

Molecular profile of adult primary leptomeningeal gliomatosis aligns with glioblastoma, IDH‐wildtype

Brain Pathology, Volume 35, Issue 4, July 2025.
The molecular profile of adult primary leptomeningeal gliomatosis closely aligned with that of adult‐type glioblastoma, IDH‐wildtype, CNS WHO grade 4. Abstract Adult primary leptomeningeal gliomatosis (PLG) is a rare, rapidly progressive and fatal disease characterized by prominent leptomeningeal infiltration by a glial tumor without an identifiable ...
Yi Zhu, Darin D. Carabenciov, Derek R. Johnson, Jorge A. Trejo‐Lopez, Aivi T. Nguyen, Aditya Raghunathan, Giuseppe Lanzino, Cristiane M. Ida, Cinthya J. Zepeda‐Mendoza, Surendra Dasari, Emilie Russler‐Germain, Sonika Dahiya, Martha Quezado, Kenneth Aldape, Caterina Giannini   +14 more
wiley   +1 more source

Aspectos epidemiológicos da meningite tuberculosa em menores de 15 anos de idade, na Grande São Paulo, Brasil, 1982 -1983 Epidemiological aspects of tuberculous meningits in children under 15 years of age, Greater S. Paulo, Brazil, 1982 -1983

Revista de Saúde Pública, 1989
Foram estudadas algumas características epidemiológicas dos casos de meningite tuberculosa ocorridos em menores de 15 anos na Grande São Paulo (Brasil), nos anos de 1982 e 1983.
Stella M.C. Nardy, Roberto Brólio, Marília Belluomini   +2 more
doaj   +1 more source

CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1‐Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis

Advanced Science, Volume 12, Issue 21, June 5, 2025.
In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han, Rui Hong, Cong Cao, Wanhua Feng, Wei Zhuang, Gui Wang, Jingchao Tang, Ya Yang, Chu Zhang, Aihua Zhou, Xuebin Qu   +10 more
wiley   +1 more source

Tuberculous meningitis of severe expression in pediatrics

Revista de la Facultad de Medicina Humana, 2020
Tuberculosis (TB) remains a major public health problem worldwide. The actual magnitude of this epidemic is underestimated due to difficulties in diagnosis in children and the limited reporting of this disease.
Guiliana Reyes Florián, Martin Seminario-Aliaga   +1 more
doaj   +1 more source