Results 161 to 170 of about 1,747,294 (351)

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Bioequivalence and Safety of Two Amisulpride Formulations in Healthy Chinese Subjects Under Fasting and Fed Conditions: A Randomized, Open‑Label, Single‑Dose, Crossover Study

Drugs in R&D
Background and Objectives Amisulpride is a second-generation antipsychotic drug that selectively binds to D2 and D3 dopaminergic receptors in the limbic system.
Min Wang, Yu Peng, Hegui Yan, Zhixiang Pan, Ronghui Du, Guan Liu   +5 more
doaj   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

In Vitro Antimicrobial Activity of Contezolid Against Mycobacterium tuberculosis and Absence of Cross-Resistance with Linezolid

Microorganisms
Tuberculosis (TB) persists as a formidable global health threat, especially with the rising incidence of multidrug-resistant strains. This study aimed to evaluate the in vitro activity of contezolid, a novel oxazolidinone antibiotic, against ...
Li Wang, Jianxia Chen, Yifan He, Ruijuan Zheng, Jie Wang, Xiaochen Huang, Wei Sha, Lianhua Qin   +7 more
doaj   +1 more source

Bridging Psychological Stress and Skin Cellular Aging: Flavonoids as a Dual‐Action Therapeutic Strategy

Phytotherapy Research, EarlyView.
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte, Sílvia Santos Pedrosa, P. Raaj Khusial, Ana Raquel Madureira   +3 more
wiley   +1 more source

Deciphering the population dynamics and drug-resistance characteristics of extrapulmonary tuberculosis: genomic and clinical insights from a Chinese hospital

Frontiers in Cellular and Infection Microbiology
IntroductionExtrapulmonary tuberculosis (EPTB) is characterized by atypical clinical symptoms, difficult diagnosis, and high mortality, so it is very important to know the prevalence and drug resistance (DR) status.
Shiwei Gong, Xinyue Li, Xinyue Li, Youyi Rao, Jun Chen, Yanjie Hu, Jianjian Guo, Kai Wang, Chang Liu, Qian He, Yanlin Zhao, Yi Ren   +11 more
doaj   +1 more source

A Case of Palmoplantar Vesiculobullous Lesions

JEADV Clinical Practice, EarlyView.
Ali Abid, Kelvin Truong, Jing Jing Li, Artiene Tatian   +3 more
wiley   +1 more source

Prognostic Value of a Cardiopulmonary Exercise Testing‐Derived Summed Score in Idiopathic Pulmonary Fibrosis and Connective Tissue Disease‐Associated Interstitial Lung Disease: A Prospective Cohort Study

Respirology, EarlyView.
A cardiopulmonary exercise testing‐derived summed score effectively predicted mortality or lung transplantation risk in newly diagnosed interstitial lung disease. Higher summed scores (2–5) were associated with markedly lower event‐free survival rates.
Yu‐Lin Tsai, Kai‐Ming Chang, Chung‐Shih Chin, Chiann‐Yi Hsu, Yi‐Hsuan Yu, Yuan‐Yang Cheng, Pin‐Kuei Fu   +6 more
wiley   +1 more source

Tuberculosis, pulmonary cavitation, and matrix metalloproteinases.

American Journal of Respiratory and Critical Care Medicine, 2014
C. Ong, P. Elkington, J. Friedland
semanticscholar   +1 more source

Deciphering the Heterogeneity of Pulmonary Macrophages in Response to Fine Particles

Small, EarlyView.
This study introduces a dual‐labeled gold nanoparticle model to capture particle–responsive cells via integrating fluorescence‐activated cell sorting and single‐cell RNA sequencing. Fourteen macrophage subsets are identified with response and function heterogeneity, among which AMs_3, AMs_7, and recMacs_4 subsets show stronger phagocytic activation ...
Qing'e Shan, Zheng Dong, Ning Li, Zijie Zhou, Jiayu Ren, Wei Liu, Feng Xu, Yu Qi, Juan Ma, Yi Liu, Shuping Zhang, Sijin Liu   +11 more
wiley   +1 more source