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With increased focus on nontuberculous mycobacterial pulmonary disease (NTM-PD), and the improvement in detection methods, the global incidence continues to increase every year, but the diagnosis and treatment are difficult with a high misdiagnosis rate ...
Hai Lou+6 more
doaj +1 more source
Objectives The value of QuantiFERON-TB Gold In-Tube (QFT-GIT) in the diagnosis of TB varies by population, comorbidities, and other factors. In this study, we aimed to investigate factors that influence false-negative results of QFT-GIT test in the ...
Yuanyuan Yu+5 more
doaj +1 more source
Empiric treatment of pulmonary TB in the Xpert era: Correspondence of sputum culture, Xpert MTB/RIF, and clinical diagnoses. [PDF]
BackgroundClinical tuberculosis diagnosis and empiric treatment have traditionally been common among patients with negative bacteriologic test results. Increasing availability of rapid molecular diagnostic tests, including Xpert MTB/RIF and the new Xpert
Cattamanchi, Adithya+12 more
core +2 more sources
A deletion in the RD105 region confers resistance to multiple drugs in Mycobacterium tuberculosis
Background The emergence of drug-resistant strains of Mycobacterium tuberculosis (Mtb), especially those that are multidrug resistant poses a serious threat to global tuberculosis control.
Lianhua Qin+9 more
doaj +1 more source
Association of IL4RA and IL-8 polymorphism in predicting susceptibility towards tuberculosis
Mycobacterium tuberculosis is an infectious bacterial disease frequently affecting the lungs. With two fatalities from tuberculosis (TB) occurring every three minutes, India has the highest disease burden.
Jyotish K+8 more
doaj +1 more source
The detection of airborne transmission of tuberculosis from HIV-infected patients, using an in vivo air sampling model [PDF]
Background. Nosocomial transmission of tuberculosis remains an important public health problem. We created an in vivo air sampling model to study airborne transmission of tuberculosis from patients coinfected with human immunodeficiency virus (HIV) and ...
A. Gonzalez+40 more
core +2 more sources
Malignant pleural mesothelioma (MPM) is the most common primary malign tumour of pleura. The aim of this study was to evaluate cases of MPM diagnosed and treated in Clinic for Pulmonary Diseases and Tuberculosis “Podhrastovi” during ten-year period (1998-
Vesna Čukić+5 more
doaj +1 more source
Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities [PDF]
Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to our inability to detect and treat all infectious cases of pulmonary
Alexandre Harari+118 more
core +2 more sources
"HETEROSEROTHERAPY" IN PULMONARY TUBERCULOSIS. [PDF]
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Perkins, J. J.+2 more
openaire +3 more sources
Background Rapid identification of pathogenic Mycobacterium species is critical for a successful treatment. However, traditional method is time-consuming and cannot discriminate isolated non-tuberculosis mycobacteria (NTM) at species level.
Qing Zhang, Heping Xiao, Liping Yan
doaj +1 more source